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Punto di Riferimento
per Medici e Operatori Sanitari
per Medici e Operatori Sanitari
LIBRERIA STUDIUM
Precision Molecular Pathology of Aggressive B-Cell Lymphomas
Crane, Loghavi
Editore
Springer
Anno
2023
Pagine
438
ISBN
9783031468414
200,00 €
DA SCONTARE
Written by experts in the field, Precision Molecular Pathology of Aggressive B-Cell Lymphomas contains the most recent revisions from the 5th Edition WHO and 2022 International Consensus Classification diagnostic categories and serves as an important resource for trainees, pathologists, haematologist/oncologists, other clinicians involved in lymphoma care and lymphoma researchers. It provides a comprehensive yet concise synthesis of emerging molecular advances that inform patient care and improve understanding of disease mechanisms. In addition, it provides the necessary background to how molecular techniques are performed to enable the reader to better interpret and critically evaluate relevant and emerging data.
As part of the Molecular Pathology Library series, this book focuses specifically on aggressive B-cell lymphomas given the increasing relevance of molecular data for diagnosis and treatment of these disorders. This evidence-based text contains 25 chapters and is divided into 5 parts. Part 1 provides a brief history and background of aggressive B-cell lymphomas. Landmark events in their classification and treatment are given in order to place the substantial advances in the field in context. Part 2 reviews molecular pathology methods, including the increasing use of next generation sequencing techniques in clinical practice. Parts 3 and 4 focus on individual subtypes of aggressive B-cell lymphoma, including a summary of the diagnostic criteria and key pathologic and clinical features for each entity. Finally, Part 5 focuses on emerging molecular technologies that may significantly impact clinical practice.
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Front Matter
Pages i-xvii
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Background
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Front Matter
Pages 1-1
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Historical Perspectives in B-Cell Lymphoma Classification: From Hodgkin to WHO
- Michael E. Kallen, Sanam Loghavi, L. Jeffrey Medeiros
Pages 3-15
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Revisions to the Classification of Aggressive B-Cell Lymphomas
- Michael E. Kallen, Rima Koka
Pages 17-35
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Methods
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Front Matter
Pages 37-37
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Cytogenetics and FISH in Precision Molecular Pathology of Aggressive B-Cell Lymphomas
- Yi Ning, Jocelyn Reader
Pages 39-45
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Introduction to Next-Generation Sequencing
- Tauangtham Anekpuritanang, Philipp W. Raess, Richard D. Press
Pages 47-82
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Next-Generation Sequencing-Based Methods for the Detection of B-Cell Clonality
- Karin P. Miller, Rena R. Xian
Pages 83-102
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Next-Generation Sequencing Detection of Copy Number Variants and Translocations
- James P. Solomon, Wei Song
Pages 103-112
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RNA-Seq and RNA Expression Profiling
- Michael M. Franklin, Laura N. Toth, Devon Chabot-Richards
Pages 113-123
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Flow Cytometry Applications in the Diagnosis and Classification of Aggressive B-Cell Lymphoma
- Hong Fang, Sa A. Wang
Pages 125-142
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Molecular Characteristics of Specific Large B-Cell Lymphoma Subtypes
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Front Matter
Pages 143-143
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- Alisha D. Ware, Michael J. Borowitz
Pages 145-157
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Precision Medicine in Burkitt and Burkitt-Like Lymphomas
- Shunyou Gong
Pages 159-178
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Precision Medicine in Diffuse Large B-Cell Lymphoma
- Siba El Hussein, Francisco Vega
Pages 179-211
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Mediastinal Gray Zone Lymphoma
- Julie Y. Li, Laura M. Wake, Gang Zheng
Pages 213-219
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- Tatyana Gindin, Shafinaz Hussein
Pages 221-243
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Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type
- Mushal Noor, Gabriel C. Caponetti
Pages 245-261
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Epstein-Barr Virus-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
- Mahsa Khanlari, Pei Lin
Pages 263-280
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- Christian Salib, Julie Teruya-Feldstein
Pages 281-294
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Molecular Characteristics of Specific Large B-Cell Lymphoma Subtypes
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T-Cell/Histiocyte-Rich Large B-Cell Lymphoma
- Kirill A. Lyapichev, Joseph D. Khoury
Pages 295-303
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ALK Positive Large B-Cell Lymphoma
- Sharmila Ghosh, Christian Salib, Julie Teruya-Feldstein
Pages 305-313
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- Michael E. Kallen, Sanam Loghavi
Pages 315-328
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Large B-Cell Lymphomas with IRF4 Rearrangements
- Rajeswari Jayakumar, Laura M. Wake
Pages 329-337
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- Jonathon Gralewski, Daniel Babu
Pages 339-350
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Immune Deficiency Related Lymphoproliferative Disease
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Front Matter
Pages 351-351
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- Mehrnoosh Tashakori, Sanam Loghavi
Pages 353-358
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Genetic Landscape of Post-transplant Lymphoproliferative Disorders
- Rima Koka, Michael E. Kallen
Pages 359-377
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Epstein-Barr Virus-Positive Mucocutaneous Ulcer
- Tapan Bhavsar
Pages 379-391
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Emerging Molecular Technologies
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Front Matter
Pages 393-393
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Circulating Tumor DNA in Lymphoma
- Jialing Huang, Christopher D. Gocke
Pages 395-426
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Correction to: Epstein-Barr Virus-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
- Mahsa Khanlari, Pei Lin
Pages C1-C1
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Back Matter
Pages 427-438
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