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Punto di Riferimento
per Medici e Operatori Sanitari
per Medici e Operatori Sanitari
LIBRERIA STUDIUM
WHO Classification of the Eye. Fourth edition
A.A.V.V.
Editore
WHO
Anno
2018
Pagine
223
ISBN
9789283244974
140,00 €
DA SCONTARE
The WHO Classification of Tumours of the Eye is the 12th and final volume in the 4th edition of the WHO series on the classification of human tumours. The series (also known as the Blue Books) has long been regarded by pathologists as the gold standard for the diagnosis of tumours, and it is an indispensable guide for the design of evaluations, clinical trials, and studies involving cancer. These authoritative and concise reference books provide an international standard for anyone involved in cancer research or the care of cancer patients.
Diagnostic criteria, pathological features, and genetic and other associated molecular alterations are described in a disease-oriented manner. This volume updates the existing ICD-O codes and provides new codes for use in epidemiology and cancer registration. It also provides information on clinical features, pathology, genetics, prognosis, and protective factors for each of the tumour types covered.
The editors expect that this volume will be of particular interest to pathologists, oncologists, and ophthalmologists who manage or research tumours of the eye. Sections are included on all recognized neoplasms (and their variants) of the eye, lacrimal apparatus, and conjunctiva. There have been particularly substantial changes to the classification of conjunctival neoplasia and melanoma, based on the latest information from genetic and molecular studies.
This book has been prepared by 64 contributors from 22 countries. It contains more than 400 colour images and tables, and more than 1400 references.
1 Tumours of the conjunctiva and caruncle 11
WHO classification 12
TNM classification of carcinoma of the conjunctiva 13
TNM classification of skin carcinoma of the eyelid 14
TNM classification of melanoma of the conjunctiva 15
Introduction 16
Epithelial tumours 17
Conjunctival squamous cell carcinoma 17
Conjunctival spindle cell carcinoma 19
Adenosquamous carcinoma 20
Keratoacanthoma 21
Hereditary benign intraepithelial dyskeratosis
of the conjunctiva 22
Conjunctival squamous intraepithelial neoplasia 23
Sebaceous carcinoma 25
Oncocytoma 26
Conjunctival squamous papilloma 27
Tumour-like lesions 28
Cysts 28
Reactive epithelial hyperplasia 28
Pseudoglandular and pseudoepitheliomatous
hyperplasia 29
Melanocytic tumours 30
Conjunctival melanoma 30
Conjunctival melanocytic intraepithelial neoplasia 31
Conjunctival junctional, compound,
and subepithelial naevi 33
Inflamed juvenile conjunctival naevus 35
Blue naevus of the conjunctiva 36
Spitz naevus of the conjunctiva 37
Benign epithelial melanoses of the conjunctiva 38
Haematolymphoid tumours 40
Lymphomas 40
Papillary/follicular conjunctivitis 41
Reactive lymphoid hyperplasia 42
Soft tissue tumours 44
Leiomyosarcoma 44
Rhabdomyosarcoma 44
Kaposi sarcoma 45
Angiosarcoma 47
Fibrous histiocytoma 47
Conjunctival stromal tumour 48
Myxoma 49
Haemangioma 50
Lymphangioma 51
Neurofibroma 52
Schwannoma 53
Juvenile xanthogranuloma 54
Hamartomas and choristomas 55
Epibulbar choristoma 55
Epibulbar osseous choristoma 56
Phakomatous choristoma 57
Secondary tumours 58
2 Tumours of the iris, ciliary body, and choroid 61
WHO classification 62
TNM classification of melanoma of the uvea 63
Introduction 65
Tumours of the iris 67
Iris melanoma 67
Melanocytic naevus 69
Ocular melanocytosis 70
Lisch nodule 70
Pigmented epithelial cyst 71
Implantation cyst 72
Ectopic lacrimal gland 73
Histiocytic tumours 73
Tumours of the ciliary body 76
Uveal melanocytoma 76
Adenocarcinoma 77
Ciliary body adenoma 78
Adenomatous hyperplasia 79
Reactive epithelial hyperplasia 80
Medulloepithelioma 81
Leiomyoma 83
Schwannoma 84
Glioneuroma 85
Tumours of the choroid 87
Choroidal and ciliary body melanomas 87
Choroidal and ciliary body naevi 92
Bilateral diffuse uveal melanocytic hyperplasia 93
Neurofibroma and ganglioneuroma 94
Schwannoma 95
Haemangioma 96
Osteoma 97
Primary choroidal lymphoma 98
Secondary lymphomatous infiltration 98
Leukaemic infiltration 100
Secondary tumours 102
3 Tumours of the retina and retinal pigment epithelium 105
WHO classification 106
TNM classification of retinoblastoma 107
Introduction 109
Tumours of the neurosensory retina 111
Retinoblastoma 111
Retinocytoma 117
Astrocytic hamartoma and astrocytoma 118
Nodular and massive retinal gliosis 120
Haemangioblastoma 122
Cavernous haemangioma 123
Vitreoretinal lymphoma 124
Leukaemic infiltration 126
Secondary tumours 127
Tumours of the retinal pigment epithelium 128
Adenocarcinoma 128
Adenoma 129
Reactive hyperplasia 130
Simple and combined hamartomas 130
Congenital hypertrophy 131
4 Tumours of the optic disc and optic nerve 133
WHO classification 134
Introduction 135
Primary tumours 136
Astrocytoma and glioblastoma 136
Meningioma of the optic nerve 139
Medulloepithelioma 140
Solitary fibrous tumour/haemangiopericytoma 141
Melanocytoma 142
Secondary tumours 144
5 Tumours of the lacrimal gland 147
WHO classification 148
TNM classification of carcinoma of the lacrimal gland 149
Introduction 150
Epithelial tumours 151
Adenoid cystic carcinoma 151
Mucoepidermoid carcinoma 152
Carcinosarcoma 153
Adenocarcinoma 154
Carcinoma ex pleomorphic adenoma 156
Pleomorphic adenoma 156
Myoepithelial tumours 158
Oncocytic tumours 160
Rare neoplasms 161
Epithelial–myoepithelial carcinoma 161
Low-grade intraductal carcinoma 162
Secretory carcinoma 162
Hybrid neoplasms 163
Acinic cell carcinoma 164
Warthin tumour 165
Haematolymphoid tumours 166
Lymphomas 166
Reactive lymphoid hyperplasia 167
Secondary tumours 169
6 Tumours of the lacrimal drainage system 171
WHO classification 172
Introduction 173
Epithelial tumours 174
Squamous cell carcinoma 174
Non-keratinizing squamous cell carcinoma 175
Adenocarcinoma 176
Mucoepidermoid carcinoma 177
Adenoid cystic carcinoma 178
Lymphoepithelial carcinoma 179
Exophytic papilloma 179
Inverted papilloma 180
Other tumours 182
Melanoma 182
Lymphomas 182
Secondary tumours 184
Contributors 185
Declaration of interests 189
IARC/WHO Committee for ICD-O 190
Sources of figures and tables 191
References 195
Subject index 217
List of abbreviations 223
