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Liver Cancer: Stem and Progenitor Cells
Pages 3-26
Punto di Riferimento
per Medici e Operatori Sanitari
per Medici e Operatori Sanitari
LIBRERIA STUDIUM
Tumors and Tumor-Like Lesions of the Hepatobiliary Tract
General and Surgical Pathology
Zimmermann
Editore
Springer
Anno
2017
Pagine
3559
ISBN
9783319269542
1.250,00 €
This book covers all liver tumors and lesions that clinically and radiologically mimic liver tumors. It provides readers with a comprehensive overview of this complex and rapidly evolving field. All aspects of surgical pathology are addressed, supplemented by detailed presentations of the lesions’ cell-biologic and molecular features. In addition, the methods employed for diagnosis and diagnostic algorithms are discussed. It appeals to pathologists and hepatologists and serves as an invaluable aid to diagnosis.The field of liver tumors and tumor-like lesions in adults and children has experienced tremendous advances in recent years. Specifically, the recognition of novel entities, deepened insights into known tumors, and refinement of classifications have necessitated continual updates and reappraisals. In addition, previous understanding of hepatic carcinogenesis and tumor progression has been transformed by the very rapid evolution of our understanding of cell biology, genomics, signaling pathways, cell interactions, and mechanisms of invasion and spread of hepatic tumor cells. These general pathology issues must be combined with surgical pathology if a comprehensive understanding of liver tumor pathology is to be achieved.
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Hepatocellular Carcinoma (Ordinary Hepatocellular Carcinoma)
Pages 27-64
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Immunohistochemistry of Hepatocellular Carcinoma
Pages 65-90
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Invasion Patterns and Metastatic Patterns of Hepatocellular Carcinoma
Pages 91-119
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Secondary Alterations of Hepatocellular Carcinoma
Pages 121-149
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Hepatocellular Carcinoma: Prognostic Factors
Pages 151-165
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Precursor Lesions of Hepatocellular Carcinoma
Pages 167-193
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Early or Small Hepatocellular Carcinoma
Pages 195-214
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Clear Cell Hepatocellular Carcinoma and Related Tumors
Pages 215-227
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Steatotic and Steatohepatitic Hepatocellular Carcinomas and Related Neoplasms
Pages 229-250
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Hepatocellular Carcinomas with Increased Stromal Reactions
Pages 251-259
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Inflammatory Hepatic Carcinomas
Pages 261-274
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Variants of Hepatocellular Carcinoma
Pages 275-292
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Hepatocellular Carcinoma with Progenitor Cell Features
Pages 293-304
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Ectopic Hepatocellular Carcinoma
Pages 305-316
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Pediatric Hepatocellular Carcinoma
Pages 317-328
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Hepatoid Carcinomas (Adenocarcinomas with Hepatoid Features)
Pages 329-334
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Fibrolamellar Hepatocellular Carcinoma
Pages 335-356
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Hepatoblastoma and the Hepatoblastoma Family of Tumors
Pages 357-393
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Variants of the Hepatoblastoma Tumor Family
Pages 395-403
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Hepatoblastomas: Biology of Disease and Prognostic Factors
Pages 405-410
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Hepatoblastoma Family of Tumors: Risk Factors and Pathogenic Pathways
Pages 411-433
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Nested Stromal-Epithelial Tumor of the Liver
Pages 435-441
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Hepatocellular Adenoma
Pages 443-472
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Variants of Hepatocellular Adenoma
Pages 473-480
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Combined Hepatocellular-Cholangiocarcinoma
Pages 481-497
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Hilar/Perihilar Cholangiocarcinoma (Klatskin Tumor)
Pages 501-526
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Extrahepatic Cholangiocarcinoma: Carcinoma of the Middle and Distal Common Bile Duct (Middle and Lower Bile Duct Carcinomas)
Pages 527-547
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Intrahepatic Cholangiocarcinomas (ICCs)
Pages 549-586
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Biology of Disease and Prognostic Factors of Cholangiocarcinomas
Pages 587-604
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Etiology and Pathogenic Pathways of Cholangiocarcinoma
Pages 605-638
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Pediatric and Adolescent Cholangiocarcinoma and Related Lesions
Pages 639-643
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Intraductal Neoplasms of the Biliary Tract
Pages 645-667
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Cholangiocarcinomas Arising in Cystic Lesions of the Hepatobiliary Tract and in Pancreaticobiliary Maljunction
Pages 669-685
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Bile Duct Carcinomas with Marked Extracellular or Intracellular Mucin Accumulation: Mucinous and Signet Ring Cell Carcinomas
Pages 687-697
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Special Variants of Cholangiocarcinoma
Pages 699-716
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Clear Cell Carcinomas of the Bile Ducts
Pages 717-720
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Bile Duct Tumors with Oncocytic Features
Pages 721-725
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Mucinous Cystic Neoplasms (MCN) and Related Cystic Neoplasms of the Hepatobiliary Tract
Pages 727-748
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Benign Epithelial Tumors and Hamartomas of the Biliary Tract
Pages 749-778
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Tumors and Tumor-like Lesions of Peribiliary Glands
Pages 779-788
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Carcinomas with a Squamous Cell Lineage
Pages 791-811
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Hepatobiliary Tumors with Acinar Cell and Adenoid Cystic Cell Lineages
Pages 813-818
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Rare Malignant and Semimalignant Epithelial Neoplasms of the Biliary Tract
Pages 819-830
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Epithelial Tumors of the Liver of Uncertain Lineage
Pages 831-839
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Hepatobiliary Carcinosarcomas and Related Neoplasms
Pages 843-857
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Giant Cell Tumors of the Hepatobiliary Tract
Pages 859-864
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Mixed Tumors of the Liver and Related Neoplasms
Pages 865-872
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Cavernous and Small Vessel Hemangiomas of the Hepatobiliary Tract
Pages 875-906
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Variants of Hepatobiliary Angiomatous Tumors
Pages 907-925
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Hepatic Epithelioid Hemangioendothelioma
Pages 927-936
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Infantile Hepatic Hemangioma/Hemangioendothelioma
Pages 937-957
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Variants of Hemangioendotheliomas of the Hepatobiliary Tract
Pages 959-964
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Angiosarcoma of the Liver
Pages 965-988
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Pediatric Hepatic Angiosarcomas
Pages 989-995
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Hepatic Kaposi’s Sarcoma
Pages 997-1002
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Glomus Tumor and Glomangiopericytic Tumors of the Liver
Pages 1003-1007
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Tumor-Like Vascular Malformations
Pages 1009-1021
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Bacillary Angiomatosis and Peliosis Hepatis
Pages 1023-1037
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Lymph Vessel Tumors of the Hepatobiliary Tract
Pages 1041-1053
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Solitary Fibrous Tumor/Hemangiopericytoma of the Liver
Pages 1057-1067
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Fibroblastoid and Myofibroblastoid Tumors of the Liver and Bile Ducts
Pages 1071-1086
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Leiomyomatous Tumors of the Hepatobiliary Tract
Pages 1087-1116
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Tumors of the Striated Muscle Cell Lineage: Hepatobiliary Rhabdomyosarcoma and Rhabdomyoma
Pages 1117-1132
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Lipomatous Tumors, Liposarcoma, Benign Adipocyte-Containing Nonneoplastic Lesions, and Focal Fatty Changes of the Liver
Pages 1133-1154
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Tumors of Osseous and Chondroid Cell Lineages
Pages 1155-1160
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Gastrointestinal Stromal Tumors (GISTs) of the Liver
Pages 1161-1172
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Tumors and Tumor-Like Lesions of the Schwann Cell Lineage and the Nerve Sheath
Pages 1173-1192
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Tumors of a Granular Cell Lineage
Pages 1193-1204
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Synovial-Like Neoplasms (Synovial Sarcoma) of the Liver
Pages 1205-1213
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Malignant Fibrous Histiocytoma of the Liver: A Neoplasm of the Undifferentiated High-Grade Pleomorphic Sarcoma Group
Pages 1215-1223
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Hepatic Mesotheliomas and Related Neoplasms
Pages 1227-1237
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Perivascular Epithelioid Cell Tumors
Pages 1241-1263
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Paraganglioma of the Hepatobiliary Tract
Pages 1267-1277
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Neuroendocrine Tumors of the Hepatobiliary Tract
Pages 1279-1305
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Undifferentiated Small Cell Tumors of the Hepatobiliary Tract
Pages 1309-1328
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Primary and Secondary Malignant Melanoma, and Other Melanotic Tumors, of the Hepatobiliary Tract
Pages 1331-1355
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Malignant Rhabdoid Tumors and Tumors with Rhabdoid Features
Pages 1359-1383
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Germ Cell Tumors of the Liver
Pages 1387-1410
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Myeloid Neoplasms with an Erythroid Cell Lineage
Pages 1413-1426
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Myeloproliferative Syndromes and Thrombocythemia
Pages 1427-1453
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Myeloid Neoplasms with Eosinophil Lineage
Pages 1455-1468
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Systemic Mastocytosis and Mast Cell Tumors
Pages 1469-1485
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Acute Leukemias of Granulocytic, Erythroid, and Megakaryocytic Lineages
Pages 1487-1510
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Myeloid Neoplasms with a Monocytoid Lineage
Pages 1511-1522
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Malignant and Benign Extramedullary Tumor-Forming Myeloid Proliferations
Pages 1523-1534
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Blastic Plasmacytoid Dendritic Cell Neoplasm
Pages 1535-1538
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Hodgkin Lymphoma of the Hepatobiliary Tract
Pages 1541-1576
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B-Cell Non-Hodgkin’s Lymphomas with a Small Cell to Intermediate Cell Phenotype
Pages 1579-1599
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B-Cell Non-Hodgkin’s Lymphomas with a Small Cell to Intermediate Cell Phenotype: Special Phenotypes
Pages 1601-1616
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B-Cell Non-Hodgkin’s Lymphomas with a Blastic/Large Cell Phenotype
Pages 1617-1636
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B-Cell Non-Hodgkin’s Lymphomas with Lymphoplasmacytoid and Plasmacytic Features
Pages 1637-1658
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Amyloidogenic Immunoglobulin Chain and Non-amyloidogenic Immunoglobulin Chain Diseases
Pages 1659-1670
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B-Cell Non-Hodgkin’s Lymphomas Associated with Viral Infections
Pages 1671-1681
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T-Cell Non-Hodgkin’s Lymphomas
Pages 1683-1710
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T-Cell Non-Hodgkin’s Lymphomas: Variant Forms
Pages 1711-1719
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Posttransplant Lymphoproliferative Disorders (PTLDs)
Pages 1721-1727
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Hepatobiliary Castleman Disease
Pages 1729-1744
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Lymphoid Hyperplasia and Pseudolymphomas of the Hepatobiliary Tract
Pages 1745-1756
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Tumors of the Langerhans Cell System
Pages 1757-1783
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Neoplasms of Histiocyte/Macrophage Lineage: Histiocytic Sarcoma and Similar Neoplasms
Pages 1785-1794
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Tumors of the Dendritic Cell System
Pages 1795-1806
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Histiocytic Syndromes
Pages 1807-1833
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Mesenchymal Hamartoma of the Liver
Pages 1837-1855
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Undifferentiated (Embryonal) Sarcoma (UES)
Pages 1857-1875
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Metastatic Liver Disease: Pathological Aspects
Pages 1879-1905
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Metastatic Liver Disease: Colorectal Carcinomas
Pages 1907-1925
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Metastatic Liver Disease: Tumors Other Than Colorectal Carcinoma
Pages 1927-1946
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Metastatic Liver Disease: Secondary Alterations of Hepatic Metastases
Pages 1947-1964
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Metastatic Liver Disease: Hepatic Lymph Node Involvement
Pages 1965-1971
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Metastatic Liver Disease: Associated Liver Lesions
Pages 1973-1987
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Pathogenic Features of Liver Metastasis: Growth, Regrowth, Stem Cells, and Circulating Tumor Cells
Pages 1989-1995
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Pathogenic Features of Liver Metastasis: Mechanisms Involving Platelets, Tumor Stroma, Epithelial-Mesenchymal Transition, and the Premetastatic Niche
Pages 1997-2017
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Pathogenic Features of Liver Metastasis: The Complex Cancer Cell–Cancer Cell, and Cancer Cell–Microenvironment Interactomes
Pages 2019-2034
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Pathogenic Features of Colorectal Liver Metastasis: Prometastatic and Antimetastatic Genes
Pages 2035-2041
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Tumors and Tumor-Like Lesions of the Hepatic Ligaments
Pages 2045-2054
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Focal Nodular Hyperplasia (FNH) of the Liver
Pages 2057-2090
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Nodular Regenerative Hyperplasia and Other Noncirrhotic Nodular Hyperplastic Lesions of the Liver
Pages 2091-2116
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Pseudotumors and Related Lesions of the Hepatobiliary Tract
Pages 2119-2142
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Ectopias and Heterotopies as Tumor-Like Lesions of the Hepatobiliary Tract
Pages 2145-2169
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Tumor-Like Lesions of the Hepatobiliary Tract: Anatomical Variations and Malformations Resulting in Hepatic Mass Effects or Focal Defects
Pages 2171-2182
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Solitary Necrotic Nodule of the Liver
Pages 2183-2189
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Hepatic and Perihepatic Involvement in Pneumokonioses and Other Mineral-Induced Diseases
Pages 2191-2217
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Tumor-Like Lesions of the Hepatobiliary Tract Caused by Gallstones, Foreign Bodies, and Bile
Pages 2219-2226
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Hepatobiliary Pseudotumors Consisting of Nonneoplastic Hematopoietic Cells and Cells of the Macrophage Lineage
Pages 2227-2253
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Liver Abscesses as Pseudotumoral Lesions
Pages 2255-2277
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Tumor-Like Lesions of the Hepatobiliary Tract Caused by Mycobacterial Infections: Tuberculosis and Lepra
Pages 2279-2309
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Tumor-Like Lesions of the Hepatobiliary Tract Caused by Actinomycosis, Nocardiosis, and Botryomycosis
Pages 2311-2328
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Tumor-Like Lesions of the Hepatobiliary Tract: Granulomatous Masses in Syphilis, Brucellosis, and Cat-Scratch Disease
Pages 2329-2346
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Tumor-Like Lesions of the Hepatobiliary Tract: Specific Abscess-Forming Bacterial Infections
Pages 2347-2362
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Tumor-Like Lesions of the Hepatobiliary Tract Caused by Fungal Infections
Pages 2363-2388
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Tumor-Like Protozoal Infections of the Hepatobiliary Tract
Pages 2389-2397
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Tumor-Like Parasitic Lesions of the Hepatobiliary Tract: Liver Flukes and Other Trematodes
Pages 2399-2416
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Tumor-Like Parasitic Lesions of the Hepatobiliary Tract: Echinococcosis and Cysticercosis
Pages 2417-2431
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Tumor-Like Parasitic Lesions of the Hepatobiliary Tract: Round Worm Infestations
Pages 2433-2438
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Tumor-Like Parasitic Lesions of the Hepatobiliary Tract: Pentastomiasis
Pages 2439-2443
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Tumor-Like Necroses of the Liver: Liver Infarct and Hepatic Pseudo-infarct (Zahn’s Infarct)
Pages 2445-2453
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Cystic Hepatobiliary Lesions Mimicking Cystic Neoplasms
Pages 2457-2472
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