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Save time identifying and diagnosing diseases of the lung, mediastinum and heart with Thoracic Pathology, a volume in the Highy Yield Pathology series. Edited by noted pathologist Dr. Aliya Husain, this medical reference book is designed to help you review the key pathologic features of a full range of thoracic diseases, recognize the classic look of typical specimens, and quickly confirm your diagnoses for more than 400 discreet entities found in the lung, mediastinum, and heart.
Author Info | |
By Aliya Husain, MD, Professor of Pathology, University of Chicago Hospitals, Chicago, Illinois |
Table of Contents:
I. LUNG
A. Normal Lung
Development of Lung
Normal Lung
B. Incidental Findings
Meningothelioid (Meningothelial-Like/Meningothelial) Nodule
Osseous Metaplasia
Corpora Amylacea
C. Developmental and Pediatric Diseases
Pulmonary Hypoplasia
Congenital Pulmonary Airway Malformation (CPAM)
Pulmonary Sequestration
Bronchogenic Cyst
Peripheral Lung Cysts
Infantile (Congenital) Lobar Emphysema
Interstitial Pulmonary Emphysema (IPE)
Congenital Pulmonary Lymphangiectasis
Alveolar Capillary Dysplasia
Surfactant Dysfunction Disorders
Hyaline Membrane Disease
Bronchopulmonary Dysplasia (BPD)
Pulmonary Interstitial Glycogenosis (PIG)
Chronic Granulomatous Disease (CGD) Of Childhood
D. Pediatric Tumors
Pleuropulmonary Blastoma
Inflammatory Myofibroblastic Tumor (IMT)
Congenital Pulmonary Myofibroblastic Tumor
Metastatic Pediatric Tumors
E. Obstructive Lung (Airway) Diseases
Large Airway Diseases
Bronchiectasis
Cystic Fibrosis
Chronic Bronchitis
Asthma
Allergic Bronchopulmonary Aspergillosis
Small Airway Diseases and Emphysema
Acute Bronchiolitis
Chronic Bronchiolitis
Follicular Bronchiolitis
Bronchiolitis Obliterans/Constrictive Bronchiolitis Obliterans/Constrictive Bronchiolitis
Emphysema
F. Restrictive (Interstitial) Lung Diseases
Acute Restrictive Lung Diseases
Pulmonary Edema
Acute Lung Injury, Acute Respiratory Distress Syndrome, Diffuse Alveolar Damage
Acute Interstitial Pneumonia (AIP)
Chronic Restrictive Lung Diseases
Usual Interstitial Pneumonia (UIP)
Nonspecific Interstitial Pneumonia (NSIP)
Cryptogenic Organizing Pneumonia (COP)
IgG4-related Sclerosing Disease
Rheumatoid Arthritis (RA)
Systemic Lupus Erythematosus (SLE)
Scleroderma
Polymyositis and Dermatomyositis-Associated Lung Disease
Sjögren Syndrome
Inflammatory Bowel Disease-Associated Interstitial Lung Disease
Asbestosis
Silicosis
Coal Workers’ Pneumoconiosis (CWP)
G. Granulomatous Diseases (non-infectious)
Sarcoidosis
Hypersensitivity Pneumonitis or Extrinsic Allergic Alveolitis
Aspiration Pneumonitis
H. Smoking Related Diseases
Desquamative Interstitial Pneumonia (DIP)
Respiratory Bronchiolitis-Associated Interstitial Lung Disease (RB-ILD)
Langerhans Cell Histiocytosis (LCH)
I. Miscellaneous Diseases
Pulmonary Alveolar Proteinosis (PAP)
Pulmonary Amyloidosis
Eosinophilic Pneumonia
Lipoid Pneumonia
Lymphangioleiomyomatosis
Middle Lobe Syndrome (Right Middle Lobe Syndrome)
Acute Chest Syndrome Of Sickle Cell Disease
Intravenous Drug Abuse
J. Diseases of Vascular Origin
Pulmonary Embolism and Infarction
Arteriovenous Malformation of the Lung
Pulmonary Hypertension
Pulmonary Hypertension
Pulmonary Arterial Hypertension (PAH)
Pulmonary Veno-Occlusive Disease (PVOD)
Pulmonary Capillary Hemangiomatosis (PCH)
Chronic Thromboembolic Pulmonary Hypertension
Pulmonary Hypertension Associated with Lung Diseases Or Hypoxemia
Diffuse Pulmonary Hemorrhage Syndromes
Goodpasture Syndrome: Anti Glomerular Basement Membrane Antibody Disease
Idiopathic Pulmonary Hemosiderosis (IPH)
Vasculitis
Pulmonary Wegener Granulomatosis
Pulmonary Churg-Strauss Syndrome
K. Pulmonary Infections
Non-infectious Pulmonary Lesions in HIV/AIDS patients
Bacterial Pneumonias
Lobar Pneumonia and Bronchopneumonia
Aspiration Pneumonia
Tuberculosis
Atypical Mycobacterial Infection
Actinomycosis
Nocardiosis
Legionnaires’ Disease
Lung Abscess
Viral Pneumonia
Lymphocytic Pneumonia
Cytomegalovirus (CMV) Pneumonia
Herpes Simplex Virus (HSV) Pneumonia
Adenovirus Pneumonia
Respiratory Syncytial Virus (RSV) Pneumonia
Measles Pneumonia
Human Metapneumovirus Pneumonia
H1N1 Pneumonia
Severe Acute Respiratory Syndrome (SARS)
Fungal Pneumonia
Aspergillosis
Blastomycosis
Candidiasis
Coccidioidomycosis
Cryptococcosis
Histoplasmosis
Pneumocystis Pneumonia (PCP)
Zygomycosis
L. Complications of Therapies
Drug-Induced Lung Injury
Methotrexate
Amiodarone
Bleomycin
Cyclophosphamide
Radiation Therapy
Radiation Pneumonitis
Bacterial Pneumonias
Lung Transplantation
Lung Transplantation: Acute Rejection
Lung Transplantation: Chronic Rejection (Bronchiolitis Obliterans)
Graft versus Host Disease (GVHD) And Other Complications of Transplantation in the Lung
M. Tumors of Lung
TNM Classification of Primary Non-Small Cell Carcinoma, Small Cell Carcinoma, and Carcinoid Tumor of the Lung
Benign tumors
Squamous Papilloma
Squamous Papillomatosis
Hamartoma
Chondroma
Pneumocytoma (Sclerosing Hemangioma)
Lipoma of Lung
Pulmonary Leiomyoma
Granular Cell Tumor
Lymphangioma and Lymphangiomatosis
Rare Benign Tumors of the Lung
Epithelial Proliferations and Tumors
Airway Epithelial Hyperplasia/Metaplasia
Squamous Dysplasia and Carcinoma In Situ (CIS)
Atypical Adenomatous Hyperplasia (AAH)
Adenocarcinoma In Situ (AIS), Formerly Bronchioloalveolar Carcinoma (BAC)
Adenocarcinoma
Squamous Cell Carcinoma (SCC)
Papillary Variant of Squamous Cell Carcinoma
Clear Cell Variant of Squamous Cell Carcinoma
Small Cell Variant of Squamous Cell Carcinoma
Basaloid Variant of Squamous Cell Carcinoma
Alveolar Space-Filling Type of Peripheral Squamous Cell Carcinoma
Lymphoepithelioma-Like Carcinoma
Adenosquamous Carcinoma
Large Cell Carcinoma
Sarcomatoid Carcinoma
Pleomorphic Carcinoma
Spindle Cell Carcinoma
Giant Cell Carcinoma
Carcinosarcoma
Pulmonary Blastoma
Adenoid Cystic Carcinoma
Mucoepidermoid Carcinoma
Epithelial-Myoepithelial Carcinoma
Neuroendocrine Proliferations and Tumors
Diffuse Neuroendocrine Cell Hyperplasia
Carcinoid Tumorlet
Carcinoid Tumor
Typical Carcinoid
Atypical Carcinoid
Small Cell Carcinoma
Large Cell Neuroendocrine Carcinoma
Mesenchymal Tumors
Solitary Fibrous Tumor of Lung
Kaposi Sarcoma
Epithelioid Hemangioendothelioma
Pulmonary Synovial Sarcoma (SS)
Pulmonary Artery and Vein Sarcoma
Rhabdomyosarcoma Lung
Miscellaneous Tumors
Perivascular Epithelioid Cell tumor (PEComa, Clear Cell "Sugar" Tumor) of the Lung
Primary Pulmonary Malignant Melanoma (PPMM)
Lymphoproliferative Disorders
Extranodal Marginal Zone B-Cell Lymphoma of Bronchial-Associated Lymphoid Tissue
Lymphoid Interstitial Pneumonia (Diffuse Lymphoid Hyperplasia)
Post-Transplant Lymphoproliferative Disorders (PTLD)
Diffuse Large B-cell lymphoma (DLBCL) of the Lung
Primary Pulmonary Hodgkin Lymphoma (PPHL)
Lymphomatoid Granulomatosis
Primary Pulmonary (Extraosseous) Plasmacytoma
Metastatic Tumors
Metastases to the Lungs: Introduction
Metastatic Carcinomas
Metastatic Carcinomas: Breast and Female Genital Tract
Metastatic Carcinomas: Gastrointestinal Tract
Metastatic Carcinomas: Genitourinary Tract and Adrenal
Metastatic Carcinomas: Head and Neck
Metastatic Adult Sarcomas
Benign Metastasizing Leiomyoma (BML)
Metastatic Giant Cell Tumor
Metastatic Melanoma
II. PLEURA AND PERICARDIUM
A. Non-Neoplastic Diseases
Pleuritis
Mesothelial hyperplasia
Adenomatoid Tumor of the Pleura
B. Neoplastic Diseases
TNM Classification of Pleural Mesothelioma
Well Differentiated Papillary Mesothelioma (WDPM)
Malignant Mesothelioma of Pleura
Epithelioid Malignant Mesothelioma
Sarcomatoid Malignant Mesothelioma
Desmoplastic Malignant Mesothelioma
Biphasic Malignant Mesothelioma
Solitary Fibrous Tumor of Pleura and Pericardium
Calcifying Pseudotumor of Pleura/Calcifying Fibrous Pseudotumor
Pleural Synovial Sarcoma
Primitive Neuroectodermal Tumor/Skeletal Ewing Sarcoma
Desmoplastic Small Round Cell Tumor of Pleura (DSRCT)
Primary Effusion Lymphoma (PEL)
Metastases to Pleura
III. THYMUS
A. Normal Thymus
Normal Thymus
B. Non-Neoplastic Diseases
Unilocular and Multilocular Thymic cysts
Thymic Dysplasia
Acute Involution of Thymus (Stress-Induced Thymic Involution)
True Thymic Hyperplasia
Lymphoid Hyperplasia of the Thymus
C. Thymoma
General Features of Thymoma
WHO Type A Thymoma
WHO Type AB Thymoma
WHO Type B1 Thymoma
WHO Type B2 Thymoma
WHO Type B3 Thymoma
D. Other Thymic Tumors
Thymic Carcinoma
Thymic Neuroendocrine Carcinoma/Tumors
Thymolipoma
IV. MEDIASTINAL LESIONS
A. Inflammatory infectious lesions
Mediastinitis
B. Cystic lesions
Mediastinal Bronchogenic Cyst
Esophageal Cyst
Mediastinal Gastroenteric Cyst
Pericardial Cyst
C. Ectopic lesions
Mediastinal Ectopic Thyroid
Ectopic Parathyroid
D. Tumors
Neurogenic Tumors
Mediastinal Schwannoma (neurilemmoma)
Mediastinal Neurofibroma
Mediastinal Malignant Peripheral Nerve Sheath Tumor (MPNST)
Neuroblastic Tumors
Mediastinal Neuroblastoma
Mediastinal Ganglioneuroblastoma
Mediastinal Ganglioneuroma
Mediastinal Paraganglioma
Mediastinal Paraganglioma
Germ Cell Tumors
Germ Cell Tumors of Mediastinum
Lymphoproliferative Disorders
Hodgkin Lymphoma of the Mediastinum
Mediastinal T-Lymphoblastic Lymphoma (T-LBL)
Primary Mediastinal (Thymic) Large B-Cell Lymphoma (PMLBCL)
Anaplastic Large Cell Lymphoma of Mediastinum
Myeloid Sarcoma (MS)
Mediastinal Castleman Disease (CD)
Follicular Dendritic Cell (FDC) Sarcoma
Mesenchymal Tumors
Mediastinal Lymphangioma
Mediastinal Liposarcoma
Rhabdomyosarcoma
V. HEART AND VESSELS
A. Normal Heart
Normal Heart
B. Congenital Heart Disease
Atrial Septal Defect (ASD)
Ventricular Septal Defect (VSD)
Hypoplastic Left Heart Syndrome (HLHS)
Tetralogy of Fallot
C. Valvular Diseases
Degenerative Valvular Disease
Bicuspid Aortic Valve (BAV)
Aortic Valve Stenosis
Aortic Valve Insufficiency
Mitral Valve Stenosis
Mitral Valve Regurgitation
Prosthetic Valves
Endocarditis
Infectious Endocarditis
Nonbacterial Thrombotic Endocarditis (NBTE)
Rheumatic Heart Disease
Acute Rheumatic Fever and Rheumatic Heart Disease (RHD)
D. Myocardial Diseases
Lymphocytic Myocarditis
Eosinophilic Myocarditis
Giant Cell Myocarditis
Cardiac Amyloidosis (Amyloid Cardiomyopathy)
Cardiac Sarcoidosis
Dilated Cardiomyopathy
Hypertrophic Cardiomyopathy
Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy
Cardiac Hemochromatosis
Hypertensive Heart Disease
Drug Cardiotoxicity
E. Ischemic Heart Disease
Myocardial Infarction (MI)
F. Heart Transplantation
Heart Transplantation: Introduction
Antibody Mediated Rejection of the Heart
Acute Cellular Rejection of the Heart
Chronic Rejection of the Heart (Cardiac Allograft Vasculopathy)
Quilty Lesion
G. Infections
Opportunistic Cardiac Infections
H. Tumors of the heart
Benign tumors
Cardiac Myxoma
Cardiac Rhabdomyoma
Cardiac Fibroelastoma
Cardiac Fibroma
Cardiac Hemangioma
Cardiac Lipoma
Lipomatous Hypertrophy of the Interatrial Septum
Malignant tumors
Angiosarcoma of the Heart
Synovial Sarcoma of the Heart
Rare Cardiac sarcomas
Primary Cardiac Lymphoma (PCL)
Cardiac Metastasis
I. Diseases of Vessels
Atherosclerosis
Thoracic Aortic aneurysm
Aortic Dissection
Infectious Vasculitis
Giant Cell Arteritis
Takayasu Arteritis
Kawasaki Disease
Churg-Strauss Syndrome
Polyarteritis Nodosa
Microscopic Polyangiitis
Thromboangiitis Obliterans
Wegener Granulomatosis
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