Non ci sono recensioni
Vascular diseases are the leading cause of death worldwide. Distinguished clinical and surgical approaches have attempted to overcome its morbidity and mortality; still 17.9 million people die every year due to vascular affections.
Stem cell therapy has emerged as a promising therapeutic strategy. Stem cells synthesize and secrete cytokines that promote cell recruitment, immunomodulation, extracellular matrix remodeling, angiogenesis, and neuroregeneration, all of which promote regeneration. Besides that, stem cells are also capable of differentiating in various cell types, being employed in tissue engineering.
Preclinical and clinical investigations have reported efficacy of stem cell therapy for various vascular diseases. Even though results are encouraging, the studies demonstrate variation in stem cell type and origin, route and protocol for administration, and concomitant use of other treatment strategies, impairing easy interpretation of results and clinical application.
The purpose of this book is to compile and comprise the current state of the evidence regarding stem cell therapy for each vascular disease, elucidating possible clinical applications. More than an objective guide for readers on the use of this novel treatment strategy, this publication will advocate for stem cell therapy use and development and will be of significant interest to physicians in a wide range of disciplines as well as researchers.
Introduction to Stem Cell Therapy and Its Application in Vascular Diseases
Pages 1-32
Lopes, Lara Lellis Navarro Minchillo (et al.)
Types and Origin of Stem Cells
Pages 33-68
Silva Barcelos, Lucíola (et al.)
Stem Cell Delivery Techniques for Stroke and Peripheral Artery Disease
Pages 69-103
Lee, Shin-Rong (et al.)
The Ethical Challenges of Stem Cell Therapy in Vascular Disorders
Pages 105-113
Batra, Ramesh K.
Bone Marrow-Derived Cells: From the Laboratory to the Clinic
Pages 115-128
King, Justin R. (et al.)
Angiogenesis: Perspectives from Therapeutic Angiogenesis
Pages 129-153
Bethel, Monique (et al.)
Stem Cell Therapy for Diabetic Foot Ulcers
Pages 155-171
Quiroz, Hallie J. (et al.)
Venous Foot and Leg Ulcers
Pages 173-198
Tzeng, Edith (et al.)
Induced Pluripotent Stem Cell-Derived Vascular Smooth Muscle Cells for Vascular Regeneration
Pages 199-219
Dash, Biraja C.
Mesenchymal Stem Cell and Hematopoietic Stem Cell Transplantation for Vasculitis
Pages 221-230
Liao, Lianming (et al.)
Mesenchymal Stem Cell and Endothelial Progenitor Cell Transplantation for Buerger’s Disease
Pages 231-243
Liao, Lianming (et al.)
Changing the Course of Peripheral Arterial Disease Using Adult Stem Progenitor Cells
Pages 245-280
Niven, Mark (et al.)
Stem Cell Delivery for the Treatment of Arteriovenous Fistula Failure
Pages 281-297
Brahmbhatt, Akshaar N. (et al.)
Stem Cell Therapy to Improve Acute Myocardial Infarction Remodeling
Pages 299-329
Gorecka, Jolanta (et al.)
Stem Cell Therapy for Stroke
Pages 331-345
Robert, S. M. (et al.)
Use of Stem Cells in the Treatment of Erectile Dysfunction
Pages 347-365
Press, Benjamin (et al.)
Stem Cell Therapy for Ophthalmic Vascular Disease
Pages 367-384
Regatieri, Caio Vinicius (et al.)
Stem Cell Therapy Delivery in Liver Disease
Pages 385-405
Langford, John (et al.)
Stem Cell Therapy for Lymphedema
Pages 407-420
McLaughlin, Dylan (et al.)
Sei sicuro di voler eseguire questa azione?