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This book serves as a guide to the pulmonary and critical care complications of hematopoietic stem cell transplantation (HSCT). HSCT is an important therapeutic modality for a variety of malignant and non-malignant conditions. The outcomes of these patients have been improving and the number of HSCT cases is increasing around the world. These patients, however, continue to have post-transplant complications related to conditioning regimens and graft vs. host disease. Pulmonary complications following HSCT remain a major cause of morbidity and mortality in this patient population.
The book begins with an overview of HSCT and graft vs. host disease. Chapters then cover particular complications, including immunological changes in lungs, diffuse alveolar hemorrhage, bronchiolitis obliterans and pulmonary fibrosis. Other complications, including neurologic, renal, gastrointestinal, and cardiac, are covered. Chapters are comprehensive and consistent with each defining the scope of the complication, epidemiology, risk factors, diagnostic approach, management, outcome and predictors of outcome, and future directions. The book provides insight as well on matters that arise during the care of HSCT patients such as provider burnout, nursing care, intensive care unit organization, nutritional support, and pulmonary and physical rehabilitation.
This is an ideal guide for pulmonologists, critical care physicians, transplant specialists, oncologists, and relevant trainees caring for patients who have undergone HSCT.
Pages i-xxii
Pages 1-15
Pages 17-44
Pages 45-61
Pages 63-79
Pages 81-90
Pages 91-105
Pages 107-118
Pages 119-128
Pages 129-140
Pages 141-160
Pages 161-176
Pages 177-192
Pages 193-201
Pages 203-210
Pages 211-219
Pages 221-232
Pages 233-245
Pages 247-256
Pages 257-270
Pages 271-285
Pages 287-300
Pages 301-310
Pages 311-320
Pages 321-326
Pages 327-336
Pages 337-349
Pages 351-364
Pages 365-371
Pages 373-391
Pages 393-401
Pages 403-425
Pages 427-435
Pages 437-447
Pages 449-453
Pages 455-462
Pages 463-472
Pages 473-483
Pages 485-493
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