Prostate Cancer: Molecular Events and Therapeutic Modalities

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Prostate Cancer: Molecular Events and Therapeutic Modalities

Hardcover

Editore

Springer

Anno

2024

Pagine

291

ISBN

9789819746118

I prezzi indicati possono subire variazioni poiché soggetti all'oscillazione dei cambi delle valute e/o agli aggiornamenti effettuati dagli Editori.

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The book covers the various cell signaling pathways responsible for prostate cancer progression, conventional therapies used for prostate cancer treatment, new emerging therapeutics, and challenges in the treatment of cancer patients. It describes the different molecular pathways responsible for prostate cancer progression to improve readers' knowledge about the role of signaling networks, and cellular and molecular aspects of prostate cancer progression. These topics include mechanisms responsible for prostate cancer malignancy with a focus on molecular pathways. It also discusses the current challenges in prostate cancer treatment such as drug resistance and immune evasion and introduces novel therapeutics such as gene therapy and nanotherapeutics for prostate cancer.

This book is completely novel and unique and covers all aspects of prostate cancer progression and challenges in therapy while presenting solutions. Written by prestigious researchers around the world, this book will be interesting to researchers and practitioners, especially those working in urological cancers.

1. Front Matter
  
  Pages 1-1
  
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2. Anatomy and Function of Prostate
  - Mehrdad Hashemi, Vahid Tavakolpour, Sima Orouei, Mina Alimohammadi, Saba Asadi, Zeinab Khazaei Koohpar et al.
  Pages 3-21
3. Epidemiology, Risk Factors and Histopathological Profile of Prostate Cancer
  - Mehrdad Hashemi, Farnaz Azizi, Niloofar AbolfathyNajmabady, Samira Moradi, Munes Ghorbanalinia, Sima Orouei et al.
  Pages 23-42
Molecular Mechanisms
1. Front Matter
  
  Pages 43-43
  
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2. Prostate Cancer and Inflammation
  - Mehrdad Hashemi, Vahid Tavakolpour, Reza Morovatshoar, Ali Samadpour, Pezhman Shafiei Asheghabadi, Hasti Hadadian et al.
  Pages 45-70
3. Prostate Cancer, Apoptosis, Autophagy and Ferroptosis: Cell Death Mechanisms and Their Cross-talk
  - Mehrdad Hashemi, Atena Sadat Hosseini, Sajad Monjezi, Saina Hasany, Sara Binaei, Mobina Nejat et al.
  Pages 71-107
4. Prostate Cancer and Metastasis: An Emphasis on EMT Mechanism
  - Mehrdad Hashemi, Shima Hajimazdarany, Reza Morovatshoar, Abbas Amini, Amirsoheil Karami, Alireza Hajimohammad et al.
  Pages 109-134
Molecular Events
1. Front Matter
  
  Pages 135-135
  
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2. Prostate Cancer and WNT/STAT3 Signaling
  - Sareh Etemad, Mahdokht Sadat Manavi, Mahsa Haji Heidari Varnousafaderani, Ferdos Faghihkhorasani, Hajarossadat Ghaderi, Seddigheh Eslamparast Kordmahalleh et al.
  Pages 137-151
3. Prostate Cancer and EZH2 Signaling
  - Mohammed Kavei, Siavash Seifollahy Fakhr, Afsaneh Mousaei, Bita Ghaffari, Nazanin Fatemeh Fadavinia, Tara Noroozi Yeganeh et al.
  Pages 153-167
4. Prostate Cancer and PTEN/PI3K/AKT/mTOR Signaling
  - Mahshid Seyed Karimi, Ferdos Faghihkhorasani, Al-Hasnawi Rasool Riyadh Abdulwahid, Sahar Mohammadi, Atiyeh Tavakoli, Parisa Osati et al.
  Pages 169-182
5. Prostate Cancer and Noncoding RNAs: A Focus on miRNAs, lncRNAs, and circRNAs
  - Ahmad Nazari, Parisa Osati, Siavash Seifollahy Fakhr, Mahnaz Akhound-Attar, Nazanin Pazhouhesh Far, Morteza Rajabi et al.
  Pages 183-201
6. Prostate Cancer and Tumor Microenvironment
  - Ahmad Nazari, Parisa Osati, Nazanin Pazhouhesh Far, Al-Hasnawi Rasool Riyadh Abdulwahid, Ferdos Faghihkhorasani, Nasim Ebrahimi et al.
  Pages 203-219
Treatments and Challenges
1. Front Matter
  
  Pages 221-221
  
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2. Chemoresistance, Radioresistance, and Androgen Deprivation Therapy Resistance in Prostate Cancer
  - Samaneh Adelian, Amin Soltani, Michael R. Hamblin
  Pages 223-240
3. Plant-Derived Natural Products in Treatment of Prostate Cancer
  - Samaneh Adelian, Amin Soltani, Michael R. Hamblin
  Pages 241-256
4. Gene Therapy as a New Emerging Strategy for Prostate Cancer
  - Samaneh Adelian, Amin Soltani, Michael R. Hamblin
  Pages 257-272
5. Nanoparticle-Based Therapeutic Strategies in Prostate Cancer Suppression
  - Samaneh Adelian, Amin Soltani, Michael R. Hamblin
  Pages 273-291
Correction to: Prostate Cancer: Molecular Events and Therapeutic Modalities
- Gautam Sethi, Milad Ashrafizadeh, Nasim Ebrahimi
Pages C1-C1