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Molecular Basis of Breast Cancer Imaging
Pages 1-14
This volume provides a comprehensive review of the molecular mechanisms involved in precancerous lesions and benign and malignant breast tumors. Given the complex molecular pathways in breast cancer biology, the book simplifies these complex mechanisms and highlights the practical issues important for daily practice. Sections are structured to review breast carcinogenesis and the role of familial predisposition and stem cells in initiation and progression of breast cancer. In-depth chapters present morphologic and molecular correlations in precancerous and malignant breast lesions, while outlining highly practical issues that are in practice today in breast pathology, such as evaluation of estrogen, progesterone receptors, and HER-2.
Written by experts in the field, Precision Molecular Pathology of Breast Cancer is a valuable resource that covers the current practice of breast pathology and looks into the future with an emphasis on the molecular basis of breast cancer.
Molecular Basis of Breast Cancer Imaging
Pages 1-14
Familial Breast Cancer and Genetic Predisposition in Breast Cancer
Pages 15-37
Modelling the Molecular Pathology of Breast Cancer Initiation
Pages 39-50
Molecular Pathology of Precancerous Lesions of the Breast
Pages 51-62
Breast Cancer Stem Cells: Role in Tumor Initiation, Progression, and Targeted Therapy
Pages 63-77
Molecular Pathology of Pre-Invasive Ductal Carcinoma
Pages 79-93
Molecular Pathology of Lobular Carcinoma
Pages 95-105
Molecular Pathology of Hormone Regulation in Breast Cancer: Hormone Receptor Evaluation and Therapeutic Implications
Pages 107-118
Molecular Pathology of HER Family of Oncogenes in Breast Cancer: HER-2 Evaluation and Role in Targeted Therapy
Pages 119-136
Molecular Classification of Breast Cancer
Pages 137-155
Triple-Negative Breast Cancer: Subtypes with Clinical Implications
Pages 157-175
Molecular-Based Diagnostic, Prognostic and Predictive Tests in Breast Cancer
Pages 177-195
Role of MicroRNAs in Breast Cancer
Pages 197-218
Molecular Pathology of Fibroepithelial Neoplasms of the Breast
Pages 219-235
Molecular Features of Mesenchymal Tumors of the Breast
Pages 237-269
Molecular Pathology of Breast Cancer Metastasis
Pages 271-289
The Molecular Pathology of Chemoresistance During the Therapeutic Response in Breast Cancer
Pages 291-307
The Molecular Pathology of Male Breast Cancer
Pages 309-315
Specimens for Molecular Testing in Breast Cancer
Pages 317-327
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