Part 1: The Investigator's Hypothesis
1. Investigator's Hypothesis and Expression of its Corresponding Outcome

Part 2: Collective Health
2. Disease Frequency Measures
3. Health Indicators
4. Epidemiological Studies
5. Pharmacoeconomics

Part 3: Observational Studies
6. Basic Concepts in Observational Studies
7. Determination of Association Strength Between an Exposure Factor and an Event in Observational Studies
8. Increasing Accuracy in Observational Studies

Part 4: Biostatistics of Intervention Studies - The Clinical Trials
9. The Intervention Studies
10. N Estimation and N Assessment of a Published Trial
11. Organization of Variables and Endpoints
12. Measures for Results Expression of a Clinical Trial
13. Determination of Normality or Non-Normality of Data Distribution
14. Hypothesis Testing
15. Correlating Sample Data with the General Population - 95% Confidence Interval Summarizing the Steps

Part 5: Additional Concepts in Biostatistics
16. Individual and Collective Benefit and Risk Indexes Inferable from Intervention Studies
17. Statistical Assessment of Diagnostic Tests for the Clinic
18. Systematic Reviews and Meta-Analyses
19. Correlation and Regression
20. Per Protocol Analysis and Intention-to-Treat Analysis