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This book is a collection of case-based questions, directed towards and meticulously selected to cover the most common and important aspects of pediatric autoimmune disorders. Autoimmune disorders of infancy and childhood, rheumatological disorders, dermatologic autoimmune disorders, autoinflammatory disorders, and clinical immunology in solid organ and hematopoietic stem cell transplantation are among the topics covered.
Each chapter starts with a case description followed by a series of 5-6 multiple choice questions (MCQ), presenting the flow from diagnosis to treatment in a step-wise, logical manner. The text guides the reader through the stream of real clinical practice from initial presentation, differential diagnosis, next best step, lab data, and definitive diagnosis to management and adverse effects of therapy. This MCQ format along with precise, yet detailed answer ensure a quick, reality learning to the reader.
The book provides a quick guide and hands-on learning experience for pediatricians, hematologists, immunologists, transplant specialists, pulmonologists, as well as PhD and post-graduate researchers around the world.
Introduction to Autoimmunity, Secondary Immunodeficiency, and Transplantation
Pages 1-15
Harville, Terry (et al.)
Fever and Cervical Lymphadenopathy
Pages 17-24
Gamez-Gonzalez, Berenise (et al.)
Prolonged Refractory High Fever
Pages 25-30
Petty, Ross (et al.)
Pain in Both Knees
Pages 31-34
Petty, Ross (et al.)
Challenging Pain in Knee and Ankle
Pages 35-41
Jandus, Peter
Fever and Urticarial Rash
Pages 43-45
Kianiamin, Mojgan
Knee Swelling and Rash
Pages 47-51
Petty, Ross (et al.)
Malaise, Weight Loss and Intermittent Fever
Pages 53-56
Petty, Ross (et al.)
Anemia, Microhematuria and Proteinuria
Pages 57-60
Snežana, Živanović S. (et al.)
Fever, Anasarca and Arthralgia
Pages 61-64
Sifuentes-Rodriguez, Erika (et al.)
Bradycardia in a Neonate
Pages 65-69
Petty, Ross (et al.)
Annular Rash in a Neonate
Pages 71-76
Kong, Yan Ling (et al.)
Itchy Facial Rash
Pages 77-83
Kong, Yan Ling (et al.)
Muscle Weakness and Fever
Pages 85-90
Kumar, Piyush (et al.)
Pruritic Erythematous Rashes on Face and Eyelids
Pages 91-96
Kundak, Selcen (et al.)
Edema of Hands and Hypopigmented Lesions on Her Neck and Cheeks
Pages 97-102
Rodríguez-Lozano, Ana Luisa (et al.)
Asymptomatic Atrophic Plaque on the Face
Pages 103-108
Kong, Yan Ling (et al.)
Morbiliform Rash and Fever
Pages 109-113
Samorano, Luciana Paula (et al.)
Recurrent Interstitial Keratitis and Audiovestibular Dysfunction
Pages 115-120
Dzhuma, Kristina A. (et al.)
Breathlessness and Weight Loss
Pages 121-126
Shashidhara, Sowmya (et al.)
Neck Swelling and Fever
Pages 127-131
Shashidhara, Sowmya (et al.)
Puffy Face and Abdominal Distension
Pages 133-138
Shashidhara, Sowmya (et al.)
Hematuria and Abdominal Mass
Pages 139-142
Shashidhara, Sowmya (et al.)
Pitting Edema and Desquamation
Pages 143-147
Shashidhara, Sowmya (et al.)
Fever and Cutaneous Nodules
Pages 149-152
Shashidhara, Sowmya (et al.)
Neck Stiffness and Fever
Pages 153-155
Larry, Tangie Ngek (et al.)
Rash and Generalized Body Pains
Pages 157-159
Larry, Tangie Ngek (et al.)
Positive HIV and Violet Macular Rash
Pages 161-163
Larry, Tangie Ngek (et al.)
Weight Loss and Tuberculin Skin Test Anergy
Pages 165-167
Dangou, Léila (et al.)
Edema on Lower Limbs
Pages 169-171
Hounkpe, Medeton Grâce (et al.)
Asthenia and Fatigue
Pages 173-177
Bullens, Dominique M. A. (et al.)
Infections, Whitish Skin Papules and Subcutaneous Nodules
Pages 179-184
Babaei, Delara
Recurrent Pneumonia and History of Transplantation
Pages 185-188
Arriba-Méndez, Sonia (et al.)
Painful Skin Nodules, Prolonged Fever and Cervical Lymphadenopathy
Pages 189-196
Ying, Michelle N. G. (et al.)
Malaise, Laryngitis and Fever
Pages 197-202
Maier, Claus-Philipp (et al.)
Acute Myeloid Leukemia Requiring Hematopoietic Stem Cell Transplantation
Pages 203-206
Pandey, Soumya (et al.)
Discrepant Cytomegalovirus Serology Between Donor and Recipient in Hematopoietic Stem Cell Transplantation
Pages 207-209
Pandey, Soumya (et al.)
Suspected Immunodeficiency
Pages 211-215
Pandey, Soumya (et al.)
Linkage Disequilibrium Between HLA Alleles in Hematopoietic Stem Cell Transplantation
Pages 217-221
Pandey, Soumya (et al.)
T-Lymphoblastic Lymphoma
Pages 223-227
Pandey, Soumya (et al.)
No Lymphocytes in an Infant
Pages 229-236
Morillo-Gutierrez, Beatriz (et al.)
DOCK8 Deficiency and No Matched Donor
Pages 237-240
Morillo-Gutierrez, Beatriz (et al.)
Diarrhea Post-HSCT
Pages 241-245
Morillo-Gutierrez, Beatriz (et al.)
Follow-Up of a Severe Combined Immunodeficiency, Who Received Bone-Marrow Transplantation Four Decades Ago
Pages 247-249
Dieli-Crimi, Romina (et al.)
Nonalcoholic Steatohepatitis Referred for Liver Transplantation
Pages 251-254
Cooling, Laura
Acute Respiratory Distress During Stem Cell Infusion
Pages 255-258
Cooling, Laura
Acute Dyspnea After Platelet Transfusion
Pages 259-263
Cooling, Laura
Requiring Immunization After Rescue Autologous HSCT
Pages 265-271
Richter, Darko
Fever and Abdominal Pain
Pages 273-279
Eloseily, Esraa M. (et al.)
Prolonged Fever, Rash and Mucosal Bleeding
Pages 281-287
Derfalvi, Beata
Recurrent Infections, Diarrhea and Hypereosinophilia
Pages 289-293
Sule, Haskologlu (et al.)
Liver Transplantation Who Developed Pancytopenia Post-transplantation
Pages 295-303
Pandey, Soumya (et al.)
Kidney Transplant Candidate Showing Presence of Pre-formed Donor-Specific Antibodies Against a Prospective Living Donor
Pages 305-309
Pandey, Soumya (et al.)
Heart Transplant Candidate Who Required Extra-Corporal Membrane Oxygenation (ECMO)
Pages 311-318
Pandey, Soumya (et al.)
Acute Antibody-Mediated Rejection of Transplantation with Negative Prospective Crossmatch Results
Pages 319-324
Pandey, Soumya (et al.)
Kidney Transplantation in a Patient with End Stage Renal Disease (ESRD) Secondary to Focal Segmental Glomerulosclerosis
Pages 325-328
Pandey, Soumya (et al.)
Itchy Violaceous Plaques
Pages 329-335
Kong, Yan Ling (et al.)
Photosensitivity and Bullous Lesions
Pages 337-343
Ashi, (et al.)
Recurrent Bullous Lesions
Pages 345-348
Rathod, Santoshdev P. (et al.)
Refractory Blisters and Erosions
Pages 349-355
Lim, Ziying Vanessa (et al.)
Annular Blisters and Erosions
Pages 357-362
Uzun, Soner (et al.)
Vesicular Pruriginous Lesions
Pages 363-367
Didona, Dario (et al.)
Widespread Vesiculobullous Rash
Pages 369-373
Uzun, Soner (et al.)
Itchy Skin Rashes
Pages 375-379
Tavakol, Marzieh
Blisters on Back and Upper Extremities
Pages 381-386
Akoglu, Gulsen
Itchy Blisters
Pages 387-392
Kong, Yan Ling (et al.)
Sudden Onset Grouped Blisters
Pages 393-397
Uzun, Soner (et al.)
Pruritic Blisters
Pages 399-402
Das, Anupam (et al.)
Widespread Depigmented and Hypopigmented Patches
Pages 403-408
Kumar, Piyush (et al.)
Whitish Patches
Pages 409-414
Akoglu, Gulsen
Hyperpigmented Patches
Pages 415-420
Kong, Yan Ling (et al.)
Outbreaks of Erythematous and Necrotic Papules with Hemorrhagic Crusts
Pages 421-426
Kundak, Selcen (et al.)
Persistent, Annular Urticarial Plaque
Pages 427-432
Kundak, Selcen (et al.)
Yellow, Reddish Brown Skin Lesions
Pages 433-434
Shafiei, Alireza
Erythroderma
Pages 435-438
Baran, Wojciech (et al.)
Erythematous Scaly Plaques
Pages 439-444
Kothiwala, Sunil K. (et al.)
Multiple Circinate, Sterile, Flaccid, Relapsing Pustules
Pages 445-450
Kundak, Selcen (et al.)
Purpuric Macules and Oral Erosions
Pages 451-457
Agarwalla, Dipak Kr. (et al.)
Diffuse Skin Rash and Mucosal Lesions
Pages 459-463
Tavakol, Marzieh
Painful Facial Ulceration
Pages 465-468
Didona, Dario (et al.)
Patchy Hair Loss
Pages 469-474
Das, Anupam (et al.)
Concerning Weight Loss Over Three Weeks
Pages 475-477
Rahmani, Farzaneh (et al.)
Toddler with Bruising on Knees
Pages 479-482
Rahmani, Farzaneh (et al.)
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