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Doctors and the general public are increasingly recognising diseases of the vulva and vagina as a cause of sexual dysfunction, morbidity and death, yet the wide but sometimes rare range of conditions involving this area are poorly represented in most textbooks of pathology. As the first volume in the Essentials of Diagnostic Gynecological Pathology series sponsored by the British Association of Gynecological Pathologists, Pathology of the Vulva and Vagina is one of the very few dealing wholly with this subject.
Pathology of the Vulva and Vagina introduces the topic with a stylishly illustrated description of the embryology and development which is fundamental to understanding the pathogenesis and symptomatology. Subsequent chapters cover infections and non-infectious dermatoses, specifying those that can predispose to cancer. The precancerous conditions of vulval intraepithelial neoplasia, melanocytic proliferations and extra-mammary Paget’s disease are integrated respectively with accounts of human papilloma virus, malignant melanoma and recent awareness of ano-genital mammary-like glands. Advances in the recognition of potentially confusing benign conditions, prognosis and staging update the pathology of squamous and adenocarcinoma in these organs. The difficulties of sentinel node biopsy are explored and a comprehensive chapter clearly highlights the difficult differential diagnosis of mesenchymal lesions.
As most histopathology departments receive many gynecological specimens, Pathology of the Vulva and Vagina has been written to be useful diagnostically to general as well as specialist gynecological histopathologists and pathologists in training. Gynecologists, oncologists, dermatologists, genitourinary physicians and cancer nurse specialists will find expert insights here that will help in treatment and counselling of their patients.
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1 Development and Anatomy: Disorders of Development . . . . . . . . 1
Naveena Singh
2 Vulvovaginal Infections. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
Pratistadevi K. Ramdial and Eduardo Calonje
3 Noninfectious Dermatoses of the Vulva . . . . . . . . . . . . . . . . . . . . . . 47
Boštjan Luzar and Eduardo Calonje
4 Cysts, Non neoplastic Glandular Lesions,
and Glandular Neoplasms of the Vulva and Vagina . . . . . . . . . . . . 87
Asma Zaman Faruqi
5 Melanoctyic Lesions of the Vulva and Vagina . . . . . . . . . . . . . . . . . 113
Thomas Brenn and Eduardo Calonje
6 Precursors of Vulvovaginal Squamous Cell Carcinoma. . . . . . . . . 147
Richard Oparka and C. Simon Herrington
7 Squamous Cell Carcinoma and Basal Cell Carcinoma of the
Vulva and Squamous Cell Carcinoma of the Vagina . . . . . . . . . . . 167
Laurence Brown
8 Vulvovaginal Mesenchymal Lesions . . . . . . . . . . . . . . . . . . . . . . . . . 207
W. Glenn McCluggage
9 Skin Adnexal Tumors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 245
Dmitry V. Kazakov, Michal Michal, and Denisa Kacerovska
Appendices . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 273
Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 281
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