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The Contributions of Pathology to the Diagnosis and Management of GVHD: Caveats and Lessons Learned
Pages 1-10
This text provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians, pathologists and researchers with an interest in GVHD and its mimickers. The book reviews new data about risk factors affecting outcomes, pathologic features, and profiles the new WHO guidelines as well as current practices. The richly illustrated text covers the gamut of gross and histologic presentations of acute GVHD in skin, gut, liver, and additional organs affected by chronic GVHD. An engaging aspect of this book is the format of patient based cases as the focus for the major chapters teaching points. The case presentations include both infectious and toxic complications that mimic GVHD, or displaying similar morphologies. Recent up to date references on clinical investigations and pathogenesis make the reading and teaching resonant with the readers.
Pathology of Graft vs. Host Disease will serve as a very useful resource for physicians and researchers dealing with, and interested in, this challenging disease. It provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters were written by experienced transplant physicians with expertise in their fields.
The Contributions of Pathology to the Diagnosis and Management of GVHD: Caveats and Lessons Learned
Pages 1-10
Evolutions in the Clinical Management of GVHD
Pages 11-20
Early GVHD with Follicular Rash
Pages 21-34
The Basic Sequence of Injury in Acute Skin GVHD
Pages 35-45
Leukemia Cutis and Hematologic Malignancies with Cutaneous Manifestation
Pages 47-54
Lichenoid Inflammatory Phase of Chronic Skin GVHD
Pages 55-68
Cutaneous Chronic GVHD: Sclerodermatous and Morpheic Variants
Pages 69-83
Early Changes of Gut GVHD: Differential Diagnosis and Criteria for Crypt Cell Apoptosis
Pages 85-95
Persistent Gastrointestinal GVHD: The Application and Utility of Histologic Grading Schemes
Pages 97-111
Pathobiology of Fatal Gastrointestinal GVHD
Pages 113-128
Abdominal Pain and Diarrhea When It Is Not GVHD
Pages 129-142
Mucosal Chronic GVHD Affecting the Oral Pharyngeal, Esophageal, and Anogenital Regions
Pages 143-156
Pre-transplant Liver Disorders: Post-transplant Impact on Developing Venocclusive Disease/Sinusoidal Obstruction Syndrome and Other Hepatic Problems
Pages 157-168
The Pathological Spectrum of Hepatic GVHD
Pages 169-183
Rapidly Progressing Cholestatic Liver Failure After Allogeneic Stem Cell Transplant from Hepatitis C Virus-Positive Donor (FCHCV)
Pages 185-195
Acute Hepatitic Onset of Liver GVHD Occurring 9 Months Post-transplant
Pages 197-206
GVHD Manifesting as Sicca Syndrome
Pages 207-214
Noninfectious Pulmonary Manifestation of GVHD: Bronchiolitis Obliterans Syndrome
Pages 215-226
Kidney Involvement in GVHD
Pages 227-236
Manifestations of Chronic GVHD in Other Organ Systems
Pages 237-244
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