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This comprehensive source on the pathogenic origins of neuropathic pain covers the detailed molecular bases of the currently known neuropathies as classified by their pathogenic origins.
Filling a critical need, this book fills the need for a resource on a syndrome that demands improved understanding by clinicians and researchers alike so that treatment options for patients are not categorically limited to a pill or a needle. If the clinician understands the origins of a patients' neuropathic pain, they can work cooperatively toward improving it with tailored therapies that don't create societal diseconomies and that ultimately are effective in helping patients.
The book presents in detail the molecular bases of some currently known neuropathies by their pathogenetic origins, allowing clinicians to tailor more specific and more effective treatment regimens for their patients. For basic researchers, this book is a general resource to better direct research on neuropathy-specific molecular mechanisms. The improved understanding of the pathogenesis of neuropathic pain can then be used to develop more specific and more effective manipulations of these pathways.
Pages i-xvii
Pages 1-1
Nerve Growth Factor and Neuropathic Pain
Alfred Malomo Jr, Daryl I. Smith
Pages 3-25
Protein Kinase C and the Chronification of Acute Pain
Benjamin Hyers, Donald S. Fleming, Daryl I. Smith
Pages 27-53
Tumor Necrosis Factor-Alpha and the Chronification of Acute Pain
Daryl I. Smith, Hai Tran
Pages 55-84
Tetrodotoxin and Neuropathic Pain
Jimmy Liu, Daryl I. Smith
Pages 85-92
Epigenetic Alterations in the Nervous System in Neuropathic Pain
Daryl I. Smith
Pages 93-101
Pages 103-103
Pathogenesis of Neuropathic Pain: Diagnosis and Treatment
May Wathiq Al-Khudhairy, Abdullah Bakr Abolkhair, Ahmed Osama El-Kabbani
Pages 105-124
Chemotherapeutics That Impair Microtubule Function: Axonopathy and Peripheral Neuropathies
Hai Tran, Gail V. W. Johnson
Pages 125-142
Diabetic Peripheral Neuropathy
Hai Tran, Daryl I. Smith
Pages 143-153
Adaora Chima, Daryl I. Smith
Pages 155-188
Anil Arekapudi, Daryl I. Smith
Pages 189-211
Perfussion-Related Neuropathies
Amie Hoefnagel, Oscar Alam-Mendez, Michael Ibrahim
Pages 213-223
Pressure-Induced Neuropathy and Treatments
Daryl I. Smith, Syed Reefat Aziz, Stacey Umeozulu, Hai Tran
Pages 225-247
Hai Tran, Daryl I. Smith, Eric Chen
Pages 249-280
Pages 281-289
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