Section 1: Introduction
1.1:Introduction, Elizabeth J. Price and Anwar R. Tappuni
1.2:Historical background, classification and diagnostic criteria, Caroline Shiboski and Troy E. Daniels
1.3:Epidemiology and genetics of Sjögren s Syndrome, Simon Bowman
Section 2: Basic science
2.1:Biomarkers in primary Sjögren sSyndrome, Onorina Berardicurti, Charlotte G. Smith, Roberto Giacomelli, Elizabeth J. Price, and Francesca Barone
2.2:Autoantibodies and autoantigens in Sjögren s Syndrome, Aurélie Ambrosi, Albin Björk, and Marie Wahren-Herlenius
2.3:Stromal cells in Sjögren s Syndrome, Saba Nayar, Serena Colafrancesco, and Francesca Barone
Section 3: Diagnostic investigations
3.1:Clinical assessment of salivary glands function, Anwar R. Tappuni
3.2:Biopsy gland biopsy procedure and histopathology, Benjamin Fisher
3.3:Imaging in Sjögren s Syndrome, Ashok Adams
Section 4: Head and neck manifestations and clinical management
4.1:Salivary glands manifestations and management, Emily Carter
4.2:Oral manifestations and management, Anwar R. Tappuni
4.3:Dental related disease, Jennifer Fuller and Shakeel Shahdad
Section 5: Ocular manifestations and management
5.1:Ocular Manifestations of Sjögren s Syndrome, Nicola Roper, Pasquale Aragona, Maurizio Rolando, and Francisco C Figueiredo
5.2:A therapeutic strategy for Sjögren s Syndrome dry eye, Nicola Roper, Pasquale Aragona, Maurizio Rolando, and Francisco C Figueiredo
Section 6: Systemic manifestations
6.1:Cutaneous involvement and management of Sjögren s Syndrome, Thomas J Tull, Emma Benton, and David D Cruz
6.2:Musculoskeletal disease - presentation and management, Elizabeth J. Price
6.3:Renal involvement in Primary Sjögren's Syndrome, Rhys Evans and Stephen Walsh
6.4:Gastrointestinal Disease in Sjögren s syndrome, Elizabeth J. Price
6.5:Neurological complications of Sjögren s Syndrome, Aravind Ganesh, Shane Lyons, and Gabriel Yiin
6.6:Cardiovascular and Lung Manifestations of Sjögren s Syndrome, Sara Carty
6.7:Haematological Manifestations of Sjögren s Syndrome, Coziana Ciurtin and Su-Ann Yeoh
6.8:Fatigue in Sjögren s Syndrome, Coziana Ciurtin and Su-Ann Yeoh
6.9:Non-pharmacological interventions for the management of Fatigue and Constitutional Symptoms in Sjögren s Syndrome, Katie Hackett and Helen Cartner
6.1:Gynaecologic and obstetric aspects in Sjögren s Syndrome, Roberta Priori, Antonina Minniti, and Serena Colafrancesco
6.11:Sjögren s Syndrome Associated Lymphoma, Saad Rassam
Section 7: Juvenile and young adult
7.1:Juvenile and young adult onset Sjögren s Syndrome, William D. Renton, Elizabeth J. Price, and A.V. Ramanan
Section 8: Sjogren s mimics and overlaps
8.1:Mimics of Sjögren s Syndrome, Nurhan Sutcliffe
8.2:Sjögren s Syndrome overlaps, Nurhan Sutcliffe and Arabella Waller
Section 9: Experimental treatments, emerging therapies and the future
9.1:Experimental therapies in primary Sjögren s Syndrome, Benjamin Fisher
9.2:Sjögren s Syndrome Summary of Clinical Management, Elizabeth J. Price and Alan Baer