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Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that manifests with a myriad of clinical and laboratory features. The assessment of SLE is comprehensive and includes different core set domains; disease activity, damage, health-related quality of life, adverse events and economic impact.
This comprehensive book is focused on the instruments and outcome measures utilized in the assessment of SLE. It targets different audiences including physicians, scientists/researchers and different health professionals interested in learning about the art of measurement in SLE. The book highlights the importance of measurement in the assessment of SLE in a clinical settings, research and clinical trials. Each of the chapters provide a systematic approach to the instruments utilized in the assessment of a specific construct in SLE (e.g., disease activity, fatigue, etc.) and incorporate a comprehensive coverage of disease specific and disease generic measures. It also discusses different patient-reported outcomes that are crucial to reflect patient perceptions of their health condition and cover constructs such as fatigue, pain, anxiety and depression, cognition, frailty, and many others.
Introduction: Metrics and Domains Measured in SLE
Pages 1-28
McGhie, Taneisha K. (et al.)
Clinical Aspects of Systemic Lupus Erythematosus
Pages 29-50
Kamen, Diane L. (et al.)
Diagnosis and Classification of Systemic Lupus Erythematosus
Pages 51-66
Johnson, Sindhu R. (et al.)
Challenges and Advances in SLE Autoantibody Detection and Interpretation
Pages 67-91
Choi, May Y. (et al.)
Childhood-Onset Systemic Lupus Erythematosus (cSLE): Is It Really Different Than Adult-Onset SLE?
Pages 93-109
Tam, Herman H. Y. (et al.)
Metrics in Disease Activity Measures in Systemic Lupus Erythematosus
Pages 111-146
Tselios, Konstantinos (et al.)
Metrics of Damage in SLE
Pages 147-157
Tofighi, Taraneh (et al.)
Metrics and Outcome Measures of Disease Activity and Damage in Childhood-Onset Systemic Lupus Erythematosus
Pages 159-180
Avar-Aydin, Pinar Ozge (et al.)
Pregnancies in Lupus: Monitoring and Metrics
Pages 181-195
Vinet, Evelyne (et al.)
Digital Data in Lupus: Metrics and Future Directions
Pages 197-212
Simard, Julia F. (et al.)
Patient-Reported Outcomes in SLE
Pages 213-227
McMorrow, Lily (et al.)
Assessment of Health-Related Quality of Life in Systemic Lupus Erythematosus
Pages 229-249
Teh, Lee-Suan (et al.)
Assessment of Cognitive Function in Systemic Lupus Erythematosus
Pages 251-285
Yuen, Kimberley (et al.)
Assessment of Depression and Anxiety in Lupus
Pages 287-301
Kwan, Andrew (et al.)
Fatigue and Pain Measurements in Systemic Lupus Erythematosus
Pages 303-335
Ajrawat, Prabjit (et al.)
Frailty: An Emerging Concept in Lupus
Pages 337-356
Hanly, John G. (et al.)
Work Disability and Prevention in SLE: A Focus on Assessment and Function
Pages 357-370
Nowrouzi-Kia, Behdin (et al.)
Metrics and Outcomes of SLE Clinical Trials
Pages 371-390
Oon, Shereen (et al.)
Metrics and Outcomes of Systemic Lupus Erythematosus in Clinical Practice
Pages 391-402
Gupta, Ambika (et al.)
Socioeconomic Impact of SLE: Metrics Utilized in the Determination of Direct and Indirect Costs and Future Directions
Pages 403-410
Barber, Megan R. W. (et al.)
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