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As a result of the rapidly growing rate of obesity worldwide, clinicians are struggling to provide the best strategies for treating obese patients with concomitant pulmonary conditions. Obesity does not simply change the epidemiology of pulmonary disease; obesity has a profound impact on the pathophysiology of common pulmonary diseases. Obesity affects the severity of asthma, response to treatment, and is likely a major modifier of the phenotype of asthma. Obesity also appears to affect response to pathogens, and as such has a major influence on response to pneumonia, and has a significant impact on outcomes pertaining to acute lung injury in the intensive care unit. Obesity and Lung Disease: A Guide to Management is the first text in the field to cover the full range of issues related to managing obese patients with pulmonary problems. All the relevant conditions, in the context of obesity, are covered, including airway inflammation, sleep apnea, asthma, pulmonary hypertension, obesity hypoventilation, as well as others. Written by an international group of experts, this important new volume is an invaluable resource for all clinicians and scientists concerned with the challenging problems surrounding obesity and lung diseases.
Chapter 1
Effects of Obesity on Lung Function
Cheryl M. Salome, Gregory G. King, and Norbert Berend
Chapter 2
Effects of Obesity on Airway Responsiveness
Stephanie A. Shore
Chapter 3
Pathogenesis of Obstructive Sleep Apnea in Obesity
Jason Paul Kirkness and Susheel P. Patil
Chapter 4
The Effects of Obesity on Immune Function and Pulmonary Host Defense
Peter Mancuso
Chapter 5
Obesity Hypoventilation Syndrome
Stephen W. Littleton and Babak Mokhlesi
Chapter 6
Effect of Obesity on the Development and Clinical Presentation of Asthma
Akshay Sood and Anne E. Dixon
Chapter 7
Treatment of the Obese Patient with Asthma
E. Rand Sutherland
Chapter 8
Obesity and Chronic Obstructive Pulmonary Disease
Frits M.E. Franssen and Emiel F.M. Wouters
Chapter 9
Obesity, The Metabolic Syndrome and Pulmonary Hypertension
Anna Ryan Hemnes and Ivan M. Robbins
Chapter 10
Obesity and Acute Lung Injury
Renee D. Stapleton and Benjamin T. Suratt
Chapter 11
Mechanical Ventilation of the Patient with Severe Obesity
Mikhail Litinski, Robert L. Owens, and Atul Malhotra
Chapter 12
Obesity and Lung Health in Children
Jason E. Lang
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