Titolo: Non-Neoplastic Hematologic Disorders

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Non-Neoplastic Hematologic Disorders

A Quick Review of Modern Diagnostic and Therapeutic Approaches

Editore

Springer

Anno

2024

Pagine

750

ISBN

9783031623721

I prezzi indicati possono subire variazioni poiché soggetti all'oscillazione dei cambi delle valute e/o agli aggiornamenti effettuati dagli Editori.

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In the current digital era with the exponential growth of medical knowledge, voluminous textbooks have gradually been replaced by the pocketbooks with tables, figures, images, and e-links to digital book versions with supplemental materials available online. The advent of novel next-generation sequencing (NGS) and multi-omics single cell methods have uncovered causative molecular mechanisms in most of the known non-neoplastic hematologic disorders. There is an urgent need for a concise and up-to-date handbook focused on non-malignant hematology.

The book describes characteristic clinical features and state-of-the-art diagnostic approaches of non-neoplastic hematologic disorders. It introduces modern molecular biomarkers with enormous diagnostic and prognostic value and novel targeted gene therapy. Differential diagnosis also includes relevant hematologic malignancies that could represent diagnostic pitfalls. Chapters include take home points for each disorder in concise and easy memorable manner. The book also provides diagnostic algorithms, novel prognostic and predictive factors, up-to-date treatment options, clinically relevant molecular signatures, and ongoing promising clinical trials if available. There are more than 100 questions and answers with comments on laboratory values, updated cytogenetic and mutational profiles.

Non-Neoplastic Hematologic Disorders: A Quick Review of Modern Diagnostic and Therapeutic Approaches provides concise clinical and laboratory information about most common non-neoplastic hematologic disorder for practicing hematologists, oncologists, hematopathologists, molecular pathologists, internal medicine specialists, pediatricians, research nurses, nurse practitioners, and trainees at all levels.

Table of contents (51 chapters)

Front Matter

Pages i-xx

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Benign Disorders of White Blood Cells
1. Front Matter
  
  Pages 1-1
  
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2. Benign Neutrophilic Disorders
  - Yumeng Zhang, Ling Zhang
  Pages 3-21
3. Benign Eosinophil Disorders
  - Chuanyi M. Lu
  Pages 23-34
4. Benign Monocytic Disorders
  - Barina Aqil, Yasmin Abaza, Juehua Gao
  Pages 35-46
5. Benign Basophil and Mast Cell Disorders
  - Parth C. Patel, Somedeb Ball
  Pages 47-60
6. Benign Lymphocytic Disorders
  - Anthony Wood, Ling Zhang, Lubomir Sokol
  Pages 61-81
7. Primary and Secondary Immunodeficiency
  - Curtis Gravenmier, Mark Ballow
  Pages 83-96
8. Benign Histiocytic and Dendritic Cell Disorders
  - Aditi Saha, Ling Zhang, Lubomir Sokol
  Pages 97-110
Disorders of Red Blood Cells
1. Front Matter
  
  Pages 111-111
  
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2. Iron Deficiency Anemia
  - Nagehan Pakasticali, Jesse M. Jaso
  Pages 113-123
3. Anemia of Inflammation
  - Udhayvir Singh Grewal, Prerna Rastogi, Sabarish Ayyappan
  Pages 125-136
4. Megaloblastic Anemia
  - Olger Nano, Meri Muminovic, Amalia Bonano-Rios, Fernando Vargas Madueno
  Pages 137-146
5. Sideroblastic Anemia
  - Yulan Jin, Natasha M. Savage
  Pages 147-158
6. Hemoglobin Disorders
  - Ziad Abuhelwa, Jinjun Cheng, Julie Li
  Pages 159-174
7. Red Blood Cell Enzymopathies
  - Clark R. Robinson, Aaron B. Boothby, Kleber Y. Fertrin
  Pages 175-187
8. Red Blood Cell Membrane Disorders
  - Shivani M. Dalal, Olger Nano, Michel Vulfovich
  Pages 189-201
9. Congenital Dyserythropoietic Anemias
  - Alexandra Dreyzin, Julie Li, Jinjun Cheng
  Pages 203-213
10. Autoimmune Hemolytic Anemia
  - Sudeepthi Bandikatla, Yumeng Zhang, Michael Jaglal
  Pages 215-227
11. Cryopathic Hemolytic Anemias
  - Stanislav Ivanov, Atif Hussein
  Pages 229-240
12. Table of contents (51 chapters)
13. Disorders of Red Blood Cells
  1. Methemoglobinemia
    - Brian D. Schlick
    Pages 241-249
  2. Extrinsic Non-immune Hemolysis
    - Caroline K. Hana, Atif M. Hussein
    Pages 251-262
  3. Pure Red Cell Aplasia
    - Nikolaos Papadantonakis, Deniz Peker
    Pages 263-274
  4. Aplastic Anemia
    - Zaker Schwabkey, Yehuda Deutsch, David Sallman
    Pages 275-289
  5. Porphyrias
    - Kai J. Rogers, Sabarish Ayyappan, Prerna Rastogi
    Pages 291-304
  6. Hereditary and Acquired Iron Overload Disorder
    - Sushmita Khadka, Lubomir Sokol
    Pages 305-315
  7. Polycythemia/Erythrocytosis
    - Aryanna Jordan, Lubomir Sokol, Ling Zhang
    Pages 317-333
14. Disorders of Platelets
  1. Front Matter
    
    Pages 335-335
    
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  2. Congenital Platelet Disorders
    - Ahmed Arfa, Loveleen C. Kang
    Pages 337-351
  3. Acquired Platelet Defects
    - Tauseef Ur Rehman, Elizabeth Rubin, Caroline K. Hana, Atif Hussein
    Pages 353-368
  4. Heparin-Induced Thrombocytopenia (HIT)
    - Shrinjaya Thapa, Akriti G. Jain, Loveleen Kang
    Pages 369-386
  5. Thrombotic Thrombocytopenic Purpura/Hemolytic-Uremic Syndrome/Atypical Hemolytic-Uremic Syndrome
    - Humaira Sarfraz, Akriti Jain, Loveleen Kang
    Pages 387-404
15. Bleeding Disorders
  1. Front Matter
    
    Pages 405-405
    
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  2. Hemophilia A and B
    - Khine Swe Shan, Nyein Thaw Dar, Manuel Martinez-Rio
    Pages 407-416
  3. Von Willebrand Disease
    - Sanjay Bridgelall, Mandy O’Leary
    Pages 417-428
  4. Rare Familial Deficiencies of Coagulation Factors II, V, VII, X, XI, and XIII
    - Abida Babu
    Pages 429-441
  5. Congenital Afibrinogenemia, Hypofibrinogenemia, Dysfibrinogenemia
    - Robert Killeen
    Pages 443-453
  6. Acquired Inhibitors of Coagulation Factors
    - Ashley M. Rose, Nathan Visweshwar
    Pages 455-466
  7. Disseminated Intravascular Coagulation
    - Mohammad Ammad Ud Din, Nathan Visweshwar
    Pages 467-475
  8. Liver Disease and Coagulopathy
    - Jerrin Joy Pullukkara
    Pages 477-488
  9. Bleeding Disorders
    1. Therapeutic Principles of Bleeding Disorders
      - Ajay B. Iyer, Ashley M. Rose
      Pages 489-501
  10. Clotting Disorders
    1. Front Matter
      
      Pages 503-503
      
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    2. Familial Thrombophilia
      - Jerel David, Wissam Hanayneh, Michael Jaglal
      Pages 505-517
    3. Antiphospholipid Syndrome
      - Dimitrios Drekolias, Wissam Hanayneh, Michael Jaglal
      Pages 519-528
    4. Principles of Antithrombotic and Fibrinolytic Therapy
      - Ruoyu Miao, Wissam Hanayneh, Michael Jaglal
      Pages 529-545
  11. Transfusion Medicine
    1. Front Matter
      
      Pages 547-547
      
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    2. Principles and Clinical Applications of Human Blood Groups and Human Leukocyte Antigen System
      - Caroline Stanek, Nirupama Singh
      Pages 549-559
    3. Red Cell Transfusion
      - Mishi Bhushan, Pankit Vachhani, Nirupama Singh
      Pages 561-578
    4. Platelet Transfusions
      - Avani M. Singh, Kaaron Benson
      Pages 579-590
    5. Plasma Product Transfusion: Fresh Frozen Plasma, Cryoprecipitate, Intravenous Immunoglobulin, and Albumin
      - Jesse J. Hubbard, Savan S. Shah
      Pages 591-599
    6. Recombinant Human Plasma Proteins in Clinical Practice
      - Zaker Schwabkey, Hassan Abushukair, Syeda Saba Kareem, Kaaron Benson
      Pages 601-617
    7. Basics of Therapeutic Apheresis
      - Mariola Vazquez Martinez, Joseph Schwartz, Hien D. Liu
      Pages 619-627
    8. Therapeutic Plasma Exchange
      - Jaime Roman Diaz, Joseph Schwartz, Hien D. Liu
      Pages 629-636
  12. Miscellaneous Disorders
    1. Front Matter
      
      Pages 637-637
      
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    2. Lipid Storage Diseases
      - Olga Sazanova, Brian D. Schlick, Lugen Chen, Prerna Rastogi
      Pages 639-656
    3. Benign Lymphadenopathy
      - Ahmed Arfa, Yu Yang, José D. Sandoval-Sus
      Pages 657-680
    4. Hypersplenism and Hyposplenism
      - Franco C. Garcia, Jennifer Eatrides
      Pages 681-691
    5. Common Infections in Patients with Hematologic Neoplasms and Hematopoietic Stem Cell Transplant
      - Oluwatobi Ozoya, Jennifer Eatrides, Ling Zhang, Ana Paula Velez, Ramon Sandin
      Pages 693-713
    6. Microorganism-Induced Benign Hematologic Conditions
      - Jennifer Eatrides, Guy Handley
      Pages 715-734
  13. Back Matter
    
    Pages 735-749