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Neurotrauma: A Comprehensive Textbook on Traumatic Brain Injury and Spinal Cord Injury aims to bring together the latest clinical practice and research in the filed of two forms of trauma to the central nervous system: namely traumatic brain injury (TBI) and spinal cord injury (SCI). Nationally, more 1.9 million Americans sustain a traumatic brain injury annually. In parallel, there are an estimate of 12,000 new cases of SCI in the United States annually. In addition, approximately 1.2 million people live with paralysis due to SCI. In recent years, dramatic advancements in the field have resulted in much improved outcomes for patients and higher standards of care. This volume details the latest research and clinical practice in the treatment of neurotrauma, in a comprehensive but easy-to-follow format. Neurotrauma is a valuable resource for any clinician involved in caring for TBI and SCI patients, clinical research professionals, researchers, medical and graduate students, and nurse specialists.
	I SEVERE TRAUMATIC BRAIN INJURY
	1 History, Overview and Human Anatomical Pathology of Traumatic Brain Injury
	Kentaro Shimoda, Shoji Yokobori, and Ross Bullock
	2 Severe TBI in Military - Medical and Surgical Interventions
	Geoff Ling
	3 Pediatric Severe Traumatic Brain Injury Management
	Kendra Woods and Michael Bell
	4 Treatment of Severe Traumatic Brain Injury in the Scandinavian Countries, with Special Emphasis on the Lund Concept
	Magnus Olivecrona
	5 Abusive Head Trauma
	Rachel Berger
	6 Traumatic Cerebral Vascular Injury
	Ramon Diaz-Arrastia
	7 Disorders of Consciousness: Common Findings in Brain Injury
	Calixto Machado
	II MILD TRAUMATIC BRAIN INJURY AND CONCUSSIONS
	8 The TRACK-TBI Approach: Redefining Severity and Outcome Assessments
	John Yue, Geoff Manley
	9 Acute Assessment of Mild Traumatic Brain Injury
	Linda Papa
	10 Current Knowledge of Blast Traumatic Brain Injury Mechanisms
	Elizabeth Fievisohn and Pamela VandeVord
	11 Adult and Pediatric Mild and Moderate Head Injury Management in Scandinavian Countries
	Johan Undén
	12 Challenges in Neurotrauma Management in India and Rapidly Growing Developing Countries
	VD Sinha, GK Prusty
	13 Chronic TBI in Veterans and Service Members: Clinical Assessment, Interventions, and Differentiation from PTSD
	Harvey Levin
	14 Chemosensory Impairment after TBI
	Nathan Zasler
	15 Return to Play, School or Work after Concussion
	Charles H. Tator
	16 The Link Between Traumatic Brain Injury and Neurodegenerative Diseases
	R. Rubenstein
	III NEUROIMAGING AND BIOMARKER ASSESSMENTS IN TBI
	17 Neuroimaging and Its Application in the Diagnosis for Early Prognostication of TBI
	Lijun Ba
	18 The Potential of Brain-Specific Blood Biomarkers for TBI Patient Management, Diagnosis and Clinical Research
	Glushakova and Ronald L. Hayes
	19 The Role of Inflammation in Traumatic Brain Injury
	Cristina Morganti-Kossmann
	20 Glutamate Receptor Peptides in Acute Neurotrauma
	Svetlana Dambinova and Galina Izykenova
	21 Serum Markers of Subclinical Brain Damage in Low Grade Chronic Concussion and Asymptomatic Cerebral Small Vessel Disease
	Sergio González-García
	22 MicroRNA Biomarkers in Traumatic Brain Injury
	Manish Bhomia
	IV TRANSLATIONAL ANIMAL STUDIES OF TBI
	23 Translational Mild Traumatic Brain Injury Research: Bridging the Gap Between Models and Clinical Uncertainty
	Eugene Park and Andrew Baker
	24 Military-relevant Rodent Models of Blast-induced Traumatic Brain Injuries
	Ibolja Cernak
	25 Pediatric TBI Models: Lessons Learned
	Ramesh Raghupathi
	26 Proteomics-based Strategies to Define Brain Tissue Biomarkers of Closed Head, Mild Traumatic Brain Injury in Translational Rodent Models
	Angela Boutte and D. Shear
	V CURRENT AND FUTURE TREATMENTS OF TBI
	27 Neuroprotection in TBI
	Dafin Muresanu
	28 Bioengineering in Brain Trauma Research
	Michelle LaPlaca
	29 Neuroregenerative Medicine in TBI
	Jinhui Chen
	30 Stem Cell Studies in Traumatic Brain Injury
	Sun Dong
	VI SPINAL CORD INJURY
	31 Spinal Cord Injury: Intensive Care Unit Neurointensive Care and Surgical Intervention
	Michael Y. Wang
	32 Animal Models of Spinal Cord Injury
	Candace Floyd
	33 Why Do We Not Have a Drug to Treat Acute Spinal Cord Injury?
	James Geddes
	34 Recent Development of Regenerative Strategies to Treat Spinal Cord Injuries
	Riyi Shi
	35 Stem Cell Therapy for Spinal Cord Injury
	Ping Wu
	VII COMMON THEMES BEETWEEN TRAUMATIC BRAIN AND SPINAL CORD INJURY
	36 Therapeutic Hypothermia and Targeted Temperature Management in the Treatment of Traumatic Brain and Spinal Cord Injury
	Dalton Dietrich
	37 Autoimmunity Responses in Traumatic Brain Injury and Spinal Cord Injury
	Zhihui Yang and F. Kobeissy, K. Wang
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