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This fully revised and expanded second edition provides a comprehensive and up-to-date overview of nasal physiology and pathophysiology. With the help of numerous tables, schematic drawings, and color photographs, it helps readers gain a better understanding of the impact of structural changes and the process of disease development, and to make treatment decisions. Each chapter has been written by a leading expert in the field and addresses one important aspect in an accessible way. Covering all four functions of the nose: respiration, defense, olfaction and cosmesis, the book discusses the various techniques for the clinical evaluation of nasal function as well as current trends and future directions in nasal physiologic research. This second edition also includes additional chapters on rhinomanometry, local nasal inflammation, T cells and B cells, and artificial intelligence for the nose. Given its scope, the book is a valuable resource for both experienced otorhinolaryngologists and novices in the field.
Front Matter
Pages i-xi
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Mucus, Goblet Cell, Submucosal Gland
Takeshi Shimizu
Pages 1-14
The Coagulation System and Rhinosinusitis
Takeshi Shimizu, Shino Shimizu
Pages 15-28
Cilia, Ciliary Movement, and Mucociliary Transport
Mark Jorissen, Martine Jaspers
Pages 29-40
Functional Defense Mechanisms of the Nasal Respiratory Epithelium
Robert C. Kern, Jennifer R. Decker
Pages 41-59
Local B-Cell and T-Cell Populations in the Pathophysiology of Chronic Rhinosinusitis with Nasal Polyposis
Kent K. Lam, Amber U. Luong
Pages 61-70
Mast Cells
Hirohisa Saito
Pages 71-76
Macrophage and Mast Cell
Hideyuki Kawauchi
Pages 77-89
The Neutrophil and Chronic Rhinosinusitis
Martin Y. Desrosiers, Shaun J. Kilty
Pages 91-95
Eosinophils in Rhinologic Diseases
Jens Ponikau, Mary Twarog, David Sherris, Hirohito Kita
Pages 97-113
Biologic Therapies for Chronic Rhinosinusitis
Michael J. Aw, Shaun J. Kilty
Pages 115-126
Nasal NO and Its Role in the Physiology of the Nose and Diagnosis
Peter W. Hellings, Glenis K. Scadding
Pages 127-129
Physiology and Pathophysiology of Sneezing and Itching: Mechanisms of the Symptoms
Murat Songu, T. Metin Onerci
Pages 131-144
The Dry Nose
Rainer K. Weber, Tanja Hildenbrand, Detlef Brehmer, Jochen A. Werner
Pages 145-155
Physiology of the Aging Nose and Geriatric Rhinitis
Yazan Eliyan, Victoria E. Varga-Huettner, Jayant M. Pinto
Pages 157-178
Nutrition and the Upper Respiratory Tract
Jim Bartley
Pages 179-183
Physiology of Lacrimal Drainage
Ali Riza Cenk Çelebi, Özlem Önerci Celebi
Pages 185-192
Intranasal Trigeminal Perception
Philippe Rombaux, Caroline Huart, Basile Landis, Thomas Hummel
Pages 193-204
Sinus Pain
Jim Bartley
Pages 205-213
Computational Fluid Dynamics of the Nasal Cavity
Ralph Mösges
Pages 215-223
Physiology and Pathophysiology of Nasal Breathing
Achim G. Beule, Giorgi Gogniashvili, Gunter H. Mlynski
Pages 225-244
Function of the Turbinates: Nasal Cycle
Achim G. Beule, Rainer K. Weber
Pages 245-253
Nasal Physiology and Pathophysiology and Their Relationship with Surgery: The Nasal Valves
Oren Friedman, Kevin Wang
Pages 255-268
Nose and Sleep Breathing Disorders
Anne-Lise Poirrier, Philippe Eloy, Philippe Rombaux
Pages 269-287
Pathophysiology of Obstructive Sleep Apnea
Kivanc Gunhan
Pages 289-305
Rhinomanometry
Zeynep Onerci Altunay
Pages 307-320
Acoustic Rhinometry
Evren Hizal, Ozcan Cakmak
Pages 321-334
New Measurement Methods in the Diagnostic of Nasal Obstruction
Gunter H. Mlynski, Giorgi Gogniashvili, Achim G. Beule
Pages 335-361
Testing of Transport and Measurement of Ciliary Activity
Mark Jorissen, Martine Jaspers
Pages 363-367
Nasal Defensive Proteins: Distribution and a Biological Function
Hideyuki Kawauchi
Pages 369-379
Olfaction
Huart Caroline, Philippe Eloy, Philippe Rombaux
Pages 381-402
Olfactory Impairement in Disease and Aging
Ayşe Elif Özdener-Poyraz, Mehmet Hakan Özdener
Pages 403-417
Electron Microscopy and the Nose
Mürvet Hayran
Pages 419-435
Genetic Background of the Rhinologic Diseases
Mehmet Gunduz, Eyyup Uctepe, Esra Gunduz
Pages 437-464
Vomeronasal Organ
Cemal Cingi, Aytuğ Altundağ, İsmail Koçak
Pages 465-469
Physiology of the Nasal Cartilages and Their Importance to Rhinosurgery
Wolfgang Pirsig
Pages 471-498
Physiology and Pathophysiology of the Growing Nasal Skeleton
H. L. Verwoerd-Verhoef, G. J. V. M. van Osch, C. D. A. Verwoerd
Pages 499-529
Physiologic Concerns During Rhinoplasty
E. B. Kern
Pages 531-550
Nasal Pulmonary Interactions
Jim Bartley
Pages 551-557
Physiologic and Dentofacial Effects of Mouth Breathing Compared to Nasal Breathing
Tulin Taner, Banu Saglam-Aydinatay
Pages 559-580
The Nose and the Eustachian Tube
Özlem Önerci Celebi
Pages 581-589
Nanomedicine and the Nose
Gürer G. Budak✠, Cengiz S. Ozkan, Mihrimah Ozkan, T. Metin Önerci
Pages 591-600
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