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Neuromuscular Junction Physiology and Pathophysiology
Pages 1-12
The third edition of this important, gold-standard title outlines a range of significant advances in the study and understanding of myasthenia gravis. The overarching goal of this new edition is identical to the first and second -- to provide the clinician and the scientist with a common resource for understanding the profound achievements in the clinical, translational, and basic sciences of neuromuscular transmission disorders. In addition to several new authors and an extensive update of all chapters, this third edition includes summaries of pre-clinical research standards for autoimmune MG, along with a broad summary of MG clinical trial performance. The now greater understanding of the clinical presentation of MuSK-related MG and identification of potential new autoantigens, including LRP-4, is discussed. The development of treatment guidelines by groups in Japan, the United Kingdom, Germany, and an international consortium is also outlined. Myasthenia Gravis and Related Disorders, Third Edition, is an invaluable resource for meeting the many and varied needs of clinicians who treat patients with myasthenia gravis.
Neuromuscular Junction Physiology and Pathophysiology
Pages 1-12
Acetylcholine Receptor Structure
Pages 13-45
Immunopathogenesis of Myasthenia Gravis
Pages 47-60
Animal Models of Myasthenia Gravis for Preclinical Evaluation
Pages 61-70
Epidemiology and Genetics of Myasthenia Gravis
Pages 71-84
Clinical Presentations of Myasthenia Gravis
Pages 85-100
Ocular Myasthenia
Pages 101-112
Thymoma-Associated Myasthenia Gravis
Pages 113-129
Electrodiagnosis of Neuromuscular Junction Disorders
Pages 131-152
Autoantibody Testing in the Diagnosis and Management of Autoimmune Disorders of Neuromuscular Transmission and Related Diseases
Pages 153-168
Treatment of Myasthenia Gravis
Pages 169-187
Neurocritical Care of Myasthenic Crisis
Pages 189-197
Thymectomy for Non-thymomatous Myasthenia Gravis
Pages 199-219
Lambert-Eaton Syndrome
Pages 221-237
Acquired Neuromyotonia
Pages 239-250
Congenital Myasthenic Syndromes
Pages 251-274
Toxic Neuromuscular Transmission Disorders
Pages 275-298
Predictors of Psychological Health in Myasthenia Gravis
Pages 299-306
Myasthenia Gravis: Classification and Outcome Measurements
Pages 307-318
Emerging Therapeutics for Myasthenia Gravis
Pages 319-333
Clinical Trial Design for Myasthenia Gravis
Pages 335-344
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