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per Medici e Operatori Sanitari
per Medici e Operatori Sanitari
LIBRERIA STUDIUM
Metastatic Bone Disease 2nd edition
An Integrated Approach to Patient Care
Randall
Editore
Springer
Anno
2024
Pagine
409
ISBN
9783031520006
150,00 €
DA SCONTARE
Skeletally related events make up approximately 20% of the cancer care economy. Advances in understanding the pathobiology and better biotargeted therapy and improved surgical technology are occurring continuously. Hundreds of thousands of patients are living longer with ever-increasing tumor burden, but patients can remain siloed in their care as they navigate across subspecialty treatments. This comprehensive text ties it all together around the patient, integrating all aspects of care.
Providing an integrated approach to the diagnosis and management of patients with metastatic bone disease (MBD), this revised and expanded text combines discussion of the pathobiology of the disease with the latest oncological and orthopedic treatment modalities. After opening with an examination of the epidemiology and impact of MBD, the biology of bone metastases are discussed, along with considerations of the tissue of origin, evaluation, biopsy andmedical therapy, including metabolic agents and biotargeting. The heart of the book presents oncological approaches (supportive, radiation and interventional) and principles of orthopedic surgical oncology, with subsequent chapters covering specific anatomy, from the pelvis to the lower extremity and the spine. Chapters on emerging surgical technology and future directions conclude the text. New to this edition are considerations around patient-reported outcomes.
Utilizing the latest clinical evidence and treatment techniques, Metastatic Bone Disease, Second Edition is standalone resource reflecting a comprehensive, patient-centric resource for all types of providers.
Front Matter
Pages i-xi
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The Problem
Front Matter
Pages 1-1
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Bone Metastases: Epidemiology and Societal Effect
Rahul Bhale, Robert U. Ashford, R. Lor Randall
Pages 3-13
Biology of Metastases and Tissue of Origin Considerations
Front Matter
Pages 15-15
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Mechanisms Underlying Osteolytic and Osteoblastic Bone Metastases
Gabriela G. Loots, Theresa A. Guise
Pages 17-35
Tissue Engineered Models to Study Bone Metastasis and Metastatic Bone Disease
Sabrina Mierswa, Gabriel Santamaria, J. Kent Leach
Pages 37-51
Biology of Bone Cancer Pain
Andrew F. Ormseth, Denis R. Clohisy
Pages 53-61
Breast Cancer Bone Metastases
Mili Arora, Helen K. Chew
Pages 63-71
Prostate Cancer Bone Metastases
Eric Granowicz, Rashmi Verma
Pages 73-83
Metastatic Primary Lung Cancer
Devon Anderson, David T. Cooke
Pages 85-90
Metastatic Bone Disease in Kidney Cancer
Manolis Pratsinis, Christopher P. Evans, Mamta Parikh
Pages 91-102
Thyroid Cancer Bone Metastasis
Elie Klam, Dev Abraham, Arnaud F. Bewley
Pages 103-108
Introduction to Multiple Myeloma and Multiple Myeloma Bone Disease
Naseem Shams Esteghamat, Mehrdad Abedi
Pages 109-121
Work-Up for Patients with Suspected Metastatic Bone Disease
Front Matter
Pages 123-123
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Evaluation of the Patient with Carcinoma of Unknown Origin Metastatic to Bone
Lauren Zeitlinger, Steven Thorpe
Pages 125-134
Biopsy Considerations
Daniel M. Lerman, Edmond O’Donnell
Pages 135-141
Medical Therapy
Front Matter
Pages 143-143
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Bisphosphonates, Denosumab, and Anabolic Agents in the Treatment of Metastatic Bone Disease
Muhammad Umar Jawad, R. Lor Randall
Pages 145-155
Biotargeting in Metastatic Bone Disease
Anna R. Cooper, Emily E. Carmody, Wakenda Tyler
Pages 157-169
Supportive Oncology
Front Matter
Pages 171-171
Supportive Oncology
Psychosocial Considerations for Patients with Metastatic Bone Disease
Amy Horyna, Abigail Inkster
Pages 173-182
Pain Management in Metastatic Bone Disease
David J. Copenhaver, Richard Applegate
Pages 183-193
When Is Hospice Appropriate? The Role for Hospice in Palliating Patients with Bone Metastases
Betty R. Ferrell
Pages 195-199
PROs
Gayathri Vijayakumar, Alan T. Blank, Amy M. Cizik
Pages 201-207
Radiation Oncology
Front Matter
Pages 209-209
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Current and Emerging Modalities
Shera B. Feinstein, Richard K. Valicenti, Xiao Zhao
Pages 211-229
Interventional Oncology
Front Matter
Pages 231-231
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Ablation and Cementation Technologies
Anthony C. Brown, Daniel M. Lerman
Pages 233-248
Principles of Orthopedic Surgical Oncology
Front Matter
Pages 249-249
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Issues Facing the Established Metastatic Bone Disease Patient: Timing/Indications for Surgery
George T. Calvert
Pages 251-262
Questions to Ask Your Medical Oncology Colleagues
Noah Federman, Amanda Loftin, Nicholas M. Bernthal, Matthew G. Cable
Pages 263-269
Consideration of the Temporal Relationship Between Surgery and Radiation Therapy
Daniel M. Lerman, Louis B. Jones
Pages 271-277
Role of Surgery in Oligometastatic Disease
George T. Calvert
Pages 279-295
Specific Anatomic Considerations for Surgery
Front Matter
Pages 297-297
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Metastatic Bone Disease: Pelvis
Joseph K. Kendal, Vishal Hegde, Nicholas M. Bernthal
Pages 299-310
Metastatic Bone Disease: Femur
Shawn L. Price
Pages 311-323
Metastatic Bone Disease: Femur and Tibia
Nicholas P. Webber, Mitchell Rawson
Pages 325-334
Metastatic Bone Disease: Foot
Judd E. Cummings
Pages 335-340
Metastatic Bone Disease: Humerus and Scapula
Michael J. Monument, Shannon K. T. Puloski
Pages 341-355
Metastatic Bone Disease: Forearm and Hand
Rashmi Agarwal, Russell Ward
Pages 357-360
Specific Anatomic Considerations for Surgery
Metastatic Bone Disease: Spine
Matthew W. Colman, William Ryan Spiker
Pages 361-383
Emergent Surgical Technologies
Front Matter
Pages 385-385
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Intraoperative Imaging and Navigation
John Groundland, John Abraham
Pages 387-396
Putting It All Together
Front Matter
Pages 397-397
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Integrative Approach with the Patient in Mind: A Glance Forward
Muhammad Umar Jawad, R. Lor Randall
Pages 399-401
Back Matter
Pages 403-409
