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This comprehensive reference work presents an up-to-date survey of the current scientific understanding of the metabolic syndrome, as well as an overview of the most significant advances in the field. The book offers a thorough reference for obesity and the metabolic syndrome and will prove an indispensable resource for clinicians, researchers and students. The obesity epidemic has generated immense interest in recent years due to the wide-ranging and significant adverse health and economic consequences that surround the problem. Much attention has been focused on excessive consumption of energy-dense food, sedentary lifestyle, and other behaviors that contribute to the pathogenesis of obesity. However, obesity is a highly complex condition that is influenced by genetic as well as environmental factors. The metabolic syndrome comprises of central obesity, hyperglycemia, hypertension, and dsylipidemia. The incidence of metabolic syndrome is growing worldwide, affecting more than one-third of adults in some countries. The metabolic syndrome increases the risk of developing coronary artery disease and stroke, and it is closely associated with fatty liver, dementia, cancer, sleep apnea, kidney failure, and other diseases. This reference work covers the full range of scientific and clinical aspects of obesity and metabolic syndrome: epidemiology, genetics, environmental factors, pathophysiology, diseases associated with obesity, pediatric obesity, and clinical management.
Pages i-xxvii
Front Matter
Pages 1-1
Overview of Metabolic Syndrome
Pages 3-14
Obesity and Metabolic Syndrome in the United States
Pages 15-32
Obesity and Metabolic Syndrome in Latin America
Pages 33-46
Obesity in Africa: A Silent Public Health Crisis
Pages 47-64
Pages 65-80
Obesity and Metabolic Syndrome in South Asians
Pages 81-101
Pages 103-121
Front Matter
Pages 123-123
Pages 125-143
Pages 145-161
Pages 163-195
Front Matter
Pages 197-197
Pages 199-215
The Built Environment and Metabolic Syndrome
Pages 217-228
Social and Community Networks and Obesity
Pages 229-246
Front Matter
Pages 247-247
Principles of Energy Homeostasis
Pages 249-266
Carbohydrate, Protein, and Fat Metabolism in Obesity
Pages 267-282
Brain Regulation of Feeding and Energy Homeostasis
Pages 283-301
Adipose Structure (White, Brown, Beige)
Pages 303-334
Pages 335-356
Gut Hormones and Metabolic Syndrome
Pages 357-372
Gut Microbiome, Obesity, and Metabolic Syndrome
Pages 373-384
Pancreatic Islet Adaptation and Failure in Obesity
Pages 385-404
Pages 405-427
Linking Inflammation, Obesity, and Diabetes
Pages 429-448
Circadian Rhythms and Metabolism
Pages 449-471
Obesity, Myokines, and Metabolic Health
Pages 473-489
Pages 491-505
Front Matter
Pages 507-507
Type 2 Diabetes: Etiology, Epidemiology, Pathogenesis, and Treatment
Pages 509-528
Dyslipidemia in Metabolic Syndrome
Pages 529-546
Obesity and Cardiovascular Disease
Pages 547-565
Non-alcoholic Fatty Liver Disease
Pages 567-583
Pages 585-602
Linking Obesity, Metabolism, and Cancer
Pages 603-620
Endocrine Disorders Associated with Obesity
Pages 621-637
Obesity, Metabolic Syndrome, and Sleep Disorders
Pages 639-658
Connecting Obesity and Reproductive Disorders
Pages 659-674
Metabolic Syndrome and Kidney Diseases
Pages 675-691
Front Matter
Pages 693-693
Diet, Exercise, and Behavior Therapy
Pages 695-712
Pharmacotherapy of Obesity and Metabolic Syndrome
Pages 713-737
Pages 739-756
Prevention and Treatment of Obesity in Children
Pages 757-783
Global, National, and Community Obesity Prevention Programs
Pages 785-799
Pages 801-815
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