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Anatomy and Embryology of the Liver
Pages 3-16
This book provides an in-depth coverage not only of liver pathology but also of diagnosis of the numerous types of liver disease, placing specific emphasis on current treatments of liver pathology including the most up-to-date information on liver transplantation.
The first part of provides an in-depth account of the liver pathology in different conditions such as Hepatits, liver ischaemia reperfusion injury, Lyme disease, cirrhotic cardiomyopathy and hepatocellular carcinoma. The second part provides a comprehensive overview of diagnostic methods. Of particular interest are chapters on the latest techniques in Patient-specific 3D printing and transient elastography (FibroScan). The final part focuses on treatment and provides a step-by step guide to the therapeutic management of liver diseases starting with pharmacological treatment and techniques including surgery and liver transplantation.
This is an invaluable book for clinicians, practitioners including academics, scientists/researchers and postgraduates to provide the newest knowledge in the field of liver pathogenesis. It is written by a multidisciplinary team of experts in hepathology, gastroenterology, and surgery especially from liver transplantation.
Florentina Radu-Ionita, MD, PhD is Consultant of Internal Medicine and Gastroenterology, Associated Professor to Gastroenterology Department, Faculty of Medicine, ”Titu Maiorescu” University, Bucharest, Romania and from 2014 is the Director of Central Military Emergency University Hospital “Dr. Carol Davila”, Bucharest, Romania. Author and co-author of 3 books, 4 chapters in specialty books, over 280 articles and scientific works, published in Romania and abroad in specialty journals or in the brochures of scientific manifestations. Moreover, is co-author of the Patent for invention no. RO 001/2017 „Method for Obtaining Fydroxyapatite Scaffolds with Predetermined Physico-Chemical Characteristics for Major Bone Reconstruction”. She is Editor-in-Chief of Romanian Journal of Military Medicine, CNCSIS C, ISSN-L1222-5126; eISSN 2501-2312; pISSN 1222-5126. She is mainly investigator and sub-investigator in over 25 international multicentric clinical studies. Associate Professor Ionita received multiple awards for his work. More important, she is supervisor in specialized training for resident doctors in gastroenterology, having numerous national universitary lectures for students and residents.
Nikolaos T. Pyrsopoulos, MD, PhD, MBA, FACP, AGAF, FAASLD, FRCP (Edin) currently serves as Professor of Medicine and Chief of Gastroenterology & Hepatology at New Jersey Medical School, Professor of Physiology, Pharmacology and Neuroscience and the Medical Director of Liver Transplantation for University Hospital. In addition, he one of the Editors in Chief for the World Journal of Hepatology and of other well-known journals in the field of Hepatology and Gastroenterology. Moreover, he has numerous publications in various scientific journals, including the Journal of Gastroenterology, Hepatology and Transplantation and is one of the authors in the book devoted to the unique field of abdominal transplantation: Intestinal and Multivisceral Transplantation. He has served in numerous national and institutional committees. In addition, he served as the Region 2 Review Board Chair for UNOS and as the Liver and Intestinal committee representative of UNOS region 2. A notorious speaker, Dr. Pyrsopoulos has given national and international talks and lectures on a variety of topics within Hepatology and Gastroenterology. He has served as Activity Director for ten annual national conferences sponsored by Rutgers, Update on Liver Disease and Digestive Disease: New Advances. Furthermore, Dr. Pyrsopoulos has participated in numerous international and national multicenter clinical research projects. He has been elected as the Rutgers NJMS Faculty Organization president. His vision is excellence in patient care, providing outstanding education to the fellows, residents and students and promoting the science of medicine by conducting research.
Mariana Jinga MD, MPH, PhD is Professor of Medicine, Head of Internal Medicine and Gastroenterology Department, Consultant of Internal Medicine and Gastroenterology at ”Dr. Carol Davila” Central Military Emergency University Hospital, Bucharest; Professor of Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania. She is member of Editorial Board of Romanian Journal of Military Medicine, and reviewer of many journals. She has participated in more than 280 scientific events and national and international training courses. More than 400 articles and scientific papers published or communicated in the country and abroad, 28 books and chapters in specialized books, in national and international publishing houses, as author, coordinator or co-author. She was principal investigator and co-investigator in 37 international clinical studies and in 13 national clinical studies, researcher in 19 national projects and in 5 international projects (EU’s Seventh Framework Programme for Research - FP 7).
Ion C. Tintoiu MD, PhD, FESC is Consultant of Internal Medicine and Cardiology, Professor of Cardiology Faculty of Medicine, “Titu Maiorescu” University of Medicine and Pharmacy, Bucharest and presently Chief of Interventional Cardiology Department, ”Carol Davila” Central Military Emergency University Hospital, Bucharest.
Professor Tintoiu received multiple awards and honors for his work, being author and co-author of 12 specialized monographs, 421 journals from multiple medical specialties. He has lectured extensively during his activity, and is a member of Editorial Board of 10 cardiology journals. Moreover, is a member of numerous PhD program committees and member of boards for Consultant examination degree.
Zhonghua Sun MD, PhD is a Professor and discipline lead of medical radiation sciences at Curtin University, Australia. His research interests include diagnostic imaging, 3D medical image visualization and processing, hemodynamic analysis of cardiovascular disease and 3D printing in medicine. He has extensive research experience in cardiovascular imaging with prolific publications in refereed journals. His research outputs include publications of 5 books, 13 book chapters and more than 250 refereed journal article publications. He is involved in many international professional societies including prestigious ones such as American Heart Association (Premium Plus Professional Member), Society of Cardiovascular Computed Tomography (Fellow of SCCT), Asian Society of Cardiovascular Imaging (Member and Auditor of ASCI), Asian Oceania Congress of Medical Physics (AOCMP), International Society of Digital Medicine (Foundation & Council Member). He serves as an academic/associate editor in five journals and editorial board member in more than 30 international journals. Furthermore, he is an invited speaker at many international conferences.
Ecaterina Bontas, MD, MSc is Specialist Physician of Internal Medicine, Specialized in Lyme Chronic Diseases and co-infections, Resident of Cardiology, Cardiology Department "Prof. C.C. Iliescu" Emergency Institute for Cardiovascular Diseases, Bucharest, Romania. In addition, she is Microsoft Certified in Repair PC and Web Designer (HTML, DHTML). Her Master & DIC Certificate of Echocardiography was completed at Imperial College of London. She has received numerous awards and fellowships during her training of Internal Medicine. She published one book as co-author, 14 chapters in specialized Publishing Houses, and 40 articles as author/co-author. In addition, she is member on life of Working Group on Myocardial Function from European Society of Cardiology - WG04/120885/20080314 and member of ILADS (The International Lyme and Associated Diseases Society).
Anatomy and Embryology of the Liver
Pages 3-16
Liver Histology
Pages 17-28
Hepatic Progenitor Cells and Biliary Tree Stem Cells
Pages 29-35
Hepatocellular Death: Apoptosis, Autophagy, Necrosis and Necroptosis
Pages 37-52
Liver Inflammation: Short Uptodate
Pages 53-63
Molecular Basis of Fibrogenesis and Angiogenesis During Chronic Liver Disease: Impact of TGF-β and VEGF on Pathogenic Pathways
Pages 65-74
Hepatotoxicity: Mechanisms of Liver Injury
Pages 75-84
Crosstalk of Molecular Signaling in Hepatocellular Carcinoma
Pages 85-94
Drug Induced Liver Injury: Mechanisms, Diagnosis, and Clinical Management
Pages 95-105
Acquired Metabolic Disorders
Pages 107-116
Vascular Disorders of the Liver
Pages 117-128
Liver Ischaemia-Reperfusion Injury
Pages 129-141
Autoimmune Hepatitis
Pages 143-151
Primary Sclerosing Cholangitis
Pages 153-159
Parasitic Liver Diseases
Pages 161-172
Viral Hepatitis B
Pages 173-180
Viral Hepatitis C
Pages 181-195
Non-B, Non-C Viral Hepatitis
Pages 197-204
The Microbiome in Liver Diseases
Pages 205-210
Polycystic Liver Diseases
Pages 211-217
Hepato- and Porto-pulmonary Hypertension
Pages 219-229
Hepatic Abscesses
Pages 231-237
Liver Cirrhosis
Pages 239-245
Primary Biliary Cholangitis
Pages 247-259
The Paucity of Interlobular Bile Ducts
Pages 261-272
Nonalcoholic Fatty Liver Disease: A Wide Spectrum Disease
Pages 273-284
Alcoholic Liver Disease
Pages 285-292
Liver Disease in Pregnancy
Pages 293-304
Cirrhotic Cardiomyopathy
Pages 305-318
Benign Liver Tumours
Pages 319-340
Liver Cancer
Pages 341-368
Acute Liver Failure
Pages 369-380
Chronic Liver Failure and Acute-on-Chronic Liver Failure
Pages 381-394
History and Physical Examination
Pages 397-406
Assessment of Liver Function
Pages 407-426
Noninvasive Biomarkers for Liver Fibrosis
Pages 427-441
Peritoneal Fluid Analysis
Pages 443-446
Measurement of the Hepatic Venous Pressure Gradient (HVPG)
Pages 447-450
Liver Biopsy for Histopathology
Pages 451-458
Liver Ultrasonography
Pages 459-471
Endoscopy in Hepatic Diseases
Pages 473-478
Dynamic and Multi-phase Contrast-Enhanced CT Scan
Pages 479-491
Patient-Specific 3D Printing in Liver Disease
Pages 493-501
Dynamic Contrast-Enhanced Ultrasonography of the Liver
Pages 503-512
Ultrasound Elastography
Pages 513-521
MR Elastography and Functional MRI of the Liver
Pages 523-531
Contrast Enhanced MR imaging of Liver
Pages 533-543
Transient Elastography in Chronic Liver Diseases
Pages 545-552
Portal Venography
Pages 553-558
Minilaparoscopy and Conventional Laparoscopy
Pages 559-565
Medical Nutrition Therapy in Liver Disease
Pages 569-586
Molecular Targets in Liver Disease
Pages 587-598
Specific Medications for Chronic Viral Hepatitis
Pages 599-609
Portal Vein Embolization (PVE) and Partial TIPE ALPPS: Beyond the Limitations of PVE
Pages 611-616
Endoscopic and Pharmacological Treatment of Esophageal Varices
Pages 617-626
Procedure for Gastric Variceal Bleeding: From BRTO to PARTO to CARTO, Three Decades of Progress
Pages 627-635
Endoscopy and Endoscopic Ultrasound for the Evaluation and Treatment of Gastric and Ectopic Varices
Pages 637-649
Portacaval Shunting for Portal Hypertension
Pages 651-660
Systemic Therapy of Advanced Liver Cancer
Pages 661-666
Embolization Therapy for Liver Cancer
Pages 667-672
Ablation of Hepatocellular Carcinoma
Pages 673-678
Laparoscopic Liver Resection
Pages 679-686
New Loco Regional Approaches to Treat Liver Cancer
Pages 687-694
Hepatic Encephalopathy
Pages 695-706
Management of Ascites
Pages 707-714
Extracorporeal Non cellular Liver Assisted Devices
Pages 715-720
Extracorporeal Cellular Liver Assisted Devices
Pages 721-726
Liver Transplantation for Acute and Chronic Liver Failure
Pages 727-739
Surgical Complications Following Liver Transplant and Their Management
Pages 741-756
Anaesthesia for Liver Transplantation
Pages 757-767
Surgery in Liver Disease
Pages 769-783
Robotic Liver Resection
Pages 785-797
Cardiac Surgery Risks in Liver Dysfunction
Pages 799-810
Future Approaches in Liver Disorders: Regenerative Medicine
Pages 811-827
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