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The field of infectious diseases drifts and shifts as new pathogens emerge or re-emerge, new treatment modalities become available, and new prevention strategies are implemented. Students of medicine and the clinically experienced teachers who help to steer their education will benefit from Clinical Infectious Diseases: A Problem-Based Approach because each chapter first defines a clinical diagnosis and moves to descriptions of common and/or classic causes of the problem while including tables, lists and descriptions of the rare and unusual etiologies we all find so fascinating. General management approaches are included to help build foundations of clinical care of infections including, but not limited to the administration of antibiotics. Reminders of classic complications seen with specific infections and/or their treatment are used to emphasize the importance of ongoing vigilance even after a specific microbiologic diagnosis has been identified. Common causes of each problem are emphasized. Unusual and rare causes are mentioned briefly with clinical clues about when to consider them. Case descriptions are used to support, facilitate, and refine the learner’s deductive clinical reasoning skills.
The book is written for a broad audience of medical trainees by a diverse group of medical experts, then edited by an infectious disease physician-scientist-educator to maintain a primary focus on the infection aspects of each problem. Basic content is reviewed first, then layered with advancing complexity. Call-out boxes are used to emphasize key concepts while figures and tables provide insights into more complex, rare but important and/or classic features of infection. As such, the book will appeal to a broad range of students and trainees from those just entering the health care field to those who have already reached subspecialty training.
Pages i-xvii
Front Matter
Pages 1-1
Bacterial Infections of the Skin and Skin Structures
Pages 3-17
Febrile Exanthems of Childhood: A Child with Fever and Rash
Pages 19-27
Acute and Chronic Lymphadenitis: Swollen Glands
Pages 29-40
Front Matter
Pages 41-41
Infectious Conjunctivitis: Pink Eye, Red Eye, and More Complex Conditions
Pages 43-53
Pages 55-62
Pages 63-68
Front Matter
Pages 69-69
Otitis, Sinusitis, and Mastoiditis: Ear or Facial Pain Following a Common Cold
Pages 71-86
Pharyngitis and Pharyngeal Space Infections: Fever, Sore Throat, Difficulty Swallowing
Pages 87-102
Pertussis and Pertussis Syndrome: A Whooping Cough
Pages 103-108
Pages 109-119
Pages 121-132
Pages 133-141
Pneumonia Caused by Endemic Fungi: Dry Cough and Fever After Visiting or Living in an Endemic Area
Pages 143-152
Tuberculosis: Hemoptysis with Unexplained Fevers and Weight Loss
Pages 153-161
Pages 163-176
SARS-CoV-2: Acute Infections, Multisystem Inflammatory Syndrome in Children, and Long-Term Sequelae
Pages 177-182
Front Matter
Pages 183-183
Pages 185-194
Infectious Myocarditis: I Cannot Breath and My Heart Is Racing
Pages 195-203
Acute Rheumatic Fever: Licks the Joints, But Bites the Heart
Pages 205-212
Pages 213-219
Front Matter
Pages 221-221
Infectious Hepatitis: Fever, Abdominal Pain, and Elevated Serum Aminotransferases
Pages 223-235
Liver Abscess: Fever with Right Sided Abdominal Pain
Pages 237-245
Infectious Gastroenteritis: Diarrhea with Fever and Vomiting
Pages 247-259
Front Matter
Pages 261-261
Urinary Tract Infections: Fever, Dysuria, and Flank Pain
Pages 263-271
Human Papillomavirus Infection: Clinically Silent Progression to Cancer and Genital Warts
Pages 273-284
Acute Scrotal Pain: Prostatitis, Epididymitis, and Orchitis
Pages 285-292
Vaginitis, Mucopurulent Cervicitis, and Pelvic Inflammatory Disease: Vaginal Discharge
Pages 293-306
Pages 307-318
Front Matter
Pages 319-319
Myelitis and Acute Flaccid Paralysis: Rapid Onset of Severe Muscle Weakness
Pages 321-329
Aseptic Meningitis: Fever, Headache, and a Stiff Neck…Not Looking So Sick
Pages 331-344
Bacterial Meningitis—Fever, Headache, and A Stiff Neck … Looking Pretty Sick
Pages 345-359
Pages 361-372
73-380
Meningoencephalitis—Fever, Altered Level of Consciousness, Seizures
Pages 381-397
Pages 399-403
Pages 405-407
Front Matter
Pages 409-409
Tetanus, Diphtheria, and Botulism
Pages 411-429
Toxic Shock Syndrome: Fever, Erythroderma, Conjunctivitis, Shock
Pages 431-438
Bacterial Toxin-Mediated Food Poisoning and Spore-Associated Foodborne Toxicoinfection
Pages 439-450
Clostridioides difficile Colitis
Pages 451-456
Bacteremia and Bacterial Sepsis: The Patient with A Positive Blood Culture
Pages 457-462
Catheter-Related Bloodstream Infections
Pages 463-475
Osteomyelitis and Septic Arthritis: Fever and Limp
Pages 477-485
Candidiasis: The Laboratory Report States that There Are Yeast in the Blood Culture!
Pages 487-493
Front Matter
Pages 495-495
Lyme Disease (Borrelia burgdorferi)
Pages 497-505
Pages 507-517
Pages 519-531
Pages 533-541
Mpox: A Fever Illness with a Vesicular Rash
Pages 543-550
Pages 551-557
African Trypanosomiasis: African Sleeping Sickness
Pages 559-565
Pages 567-573
Leprosy: A Chronic Skin Lesion that Feels Numb
Pages 575-580
Human Infections Caused by Cestodes: Tapeworms
Pages 581-597
Neurocysticercosis: First Time Seizure in a Recent Immigrant from Mexico
Pages 599-604
Human Infections Caused by Trematodes: Flukes
Pages 605-626
Human Infections Caused by Nematodes: Roundworms
Pages 627-657
Front Matter
Pages 659-659
Human Immunodeficiency Virus I: History, Epidemiology, Transmission, and Pathogenesis
Pages 661-667
Pages 669-682
Post-Exposure and Pre-Exposure HIV Prophylaxis
Pages 683-692
Front Matter
Pages 693-693
Principles of Antimicrobial Stewardship
Pages 695-706
Front Matter
Pages 707-707
Essentials of Diagnostic Microbiology
Pages 709-731
Pages 733-764
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