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This book offers a comprehensive overview of the latest standard medical procedures and surgical techniques for biliary atresia (BA), as well as the perioperative care, long-term follow-up and transitions. Experts on pediatrics in such fields as hepatology, surgery, pathology, and liver transplantation present their research findings and analyses of this rare and intractable disease of unknown etiology. In Japan, shared experience and sound understanding based on conferences and guidelines have led to standardization of management and clinical care and, as a result, better outcomes.
Providing insights into improving surgical outcomes, and including special chapters focusing on social support systems for patients and families as well as recent advances in early diagnosis, this book a valuable resource for medical professionals around the globe who are involved in treating biliary atresia. It is especially useful for pediatric hepatologists, pediatric surgeons and transplant surgeons.
Pages i-xi
Historical Overview of Biliary Atresia
Masaki Nio, Ryoji Ohi
Pages 1-6
History and Current Status of The Japanese Biliary Atresia Society
Ryoji Ohi
Pages 7-10
Definition and Classifications of Biliary Atresia
Hiroaki Kitagawa
Pages 11-17
Japanese Biliary Atresia Registry
Hideyuki Sasaki, Masaki Nio, Ryuji Okubo, Yoko Murai
Pages 19-26
Embryological and Anatomical Considerations in Biliary Atresia
Nobuyoshi Shiojiri, Ryosuke Yoshii, Yotsuba Arai
Pages 27-34
A. Inui, T. Fujisawa
Pages 35-39
Genetics and Epigenetics in the Pathogenesis of Biliary Atresia
Kazuhiko Bessho, Yoshinori Satomura
Pages 41-46
Kenichi Harada
Pages 47-53
Pathogenesis of Maternal Microchimerism
Toshihiro Muraji, Toshio Harumatsu
Pages 55-64
Epidemiology: Incidence, Gender Ratio, and Ethnic Variations
Satoshi Ieiri, Toshio Harumatsu, Toshihiro Muraji
Pages 65-67
Epidemiology: Seasonality, Family History, and Heredity
Masayuki Kubota
Pages 69-75
Epidemiology of Gestational Age, Birth Weight, and Associated Anomalies in Biliary Atresia
Takashi Akiyama
Pages 77-80
Screening and Stool Color Card System of Biliary Atresia
Masayuki Obatake
Pages 81-86
Biliary Atresia: Signs and Symptoms, Prenatal Diagnosis
Jun Fujishiro
Pages 87-90
Intracranial Hemorrhage in Biliary Atresia
Akiko Yokoi
Pages 91-94
Masayoshi Kage, Kennichi Tanikawa, Hironori Kusano
Pages 95-105
Tatsuki Mizuochi, Ken-ichiro Konishi
Pages 107-112
Differential Diagnosis of Biliary Atresia
Daiki Abukawa
Pages 113-121
Diagnostic Modalities for Biliary Atresia
Miyuki Kohno
Pages 123-131
Preoperative Management and Direct Cholangiography
Yasushi Fuchimoto
Pages 133-137
Operative Procedures: Open Kasai Procedure
Masaki Nio, Hideyuki Sasaki, Ryuji Okubo, Masatoshi Hashimoto, Yudai Nakajima
Pages 139-146
Operative Procedures: Laparoscopic Kasai Procedure
Hiroo Uchida, Chiyoe Shirota, Takahisa Tainaka
Pages 147-156
Reoperative Portoenterostomy in Biliary Atresia
Takeshi Saito
Pages 157-160
Operation Procedure: Living Donor Liver Transplantation for Biliary Atresia
Mureo Kasahara, Akinari Fukuda, Seisuke Sakamoto
Pages 161-173
Operation Procedure: Deceased Donor Liver Transplantation for Biliary Atresia
Yoshiyuki Ihara, Koichi Mizuta
Pages 175-184
Medical Treatment: Steroids/Ursodeoxycholic Acid
Shigeru Ono
Pages 185-189
Medical Treatment: Antioxidant Therapy and Kampo Medicine
Minoru Yagi, Yoshiaki Tanaka, Naoki Hashizume, Takahiro Asakawa
Pages 191-196
Current Concept About Prevention/Treatment of Postoperative Cholangitis
Kosaku Maeda
Pages 197-201
Nutritional Support for Patients with Biliary Atresia
Yuichiro Yamashiro
Pages 203-208
Protocols of Follow-up Management
Tatsuro Tajiri, Taizo Furukawa
Pages 209-215
Prognostic Indicators of Outcome in Biliary Atresia
Joel Cazares, Hiroyuki Koga, Atsuyuki Yamataka
Pages 217-225
Long-Term Complication after Portoenterostomy: Gastroesophageal and Gastrointestinal Tract Bleeding
Yutaka Kanamori
Pages 227-232
Long-Term Complications: Hypersplenism
Akira Nishi
Pages 233-235
Long-Term Complications: Cholangitis/Gall Stones
Minoru Kuroiwa
Pages 237-240
Long-Term Complications: Hepatopulmonary Syndrome
Takehisa Ueno
Pages 241-245
Long-Term Complications: Portopulmonary Hypertension
Hideaki Okajima
Pages 247-254
Long-Term Complications of Cirrhosis/Hepatic Encephalopathy
Tatsuya Suzuki, Takashi Hashimoto
Pages 255-260
Long-Term Functional Outcome and Quality of Life After Kasai Operation
Masato Shinkai, Norihiko Kitagawa, Kyoko Mochizuki, Hidehito Usui
Pages 261-267
Long-Term Results and Deformities of Intrahepatic Bile Ducts
Takashi Hashimoto, Tatsuya Suzuki
Pages 269-276
Long-Term Results of Liver Transplantation for Biliary Atresia
Yukihiro Inomata
Pages 277-288
Pregnancy and Delivery in Adult Survivors of Biliary Atresia
Tatsuo Kuroda
Pages 289-294
Biliary Atresia and Malignancy
Tsugumichi Koshinaga
Pages 295-303
Miwako Nakano
Pages 305-309
Social Support System for Biliary Atresia in Japan
Hiromu Tanaka, Masaki Nio
Pages 311-315
The Society of the Children with Biliary Atresia and Their Families
Koichi Takeuchi
Pages 317-321
International Collaboration in Biliary Atresia
Toshiharu Matsuura, Koichiro Yoshimaru, Tomoaki Taguchi
Pages 323-328
Future Prospects of Biliary Atresia
Tomoaki Taguchi, Satoko Kijima, Madoka Kuroki, Ayako Ishii, Koichiro Yoshimaru, Toshiharu Matsuura
Pages 329-339
Clinical Practice Guidelines for Biliary Atresia
Hisami Ando, Yukihiro Inomata, Tadashi Iwanaka, Tatsuo Kuroda, Masaki Nio, Akira Matsui et al.
Pages 341-350
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