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Hematopoietic Stem Cells: The Basis of Normal and Malignant Hematopoiesis
Pages 3-29
This book describes the pathogenesis and treatment of several representative hematological disorders in children, with a special focus on genetic and molecular aspects. Research on the pathogenesis of hematological disorders in children has made remarkable strides; especially molecular target therapy has shown outstanding effects in refractory and conventional therapies for childhood leukemia. The findings presented in this book will broaden readers’ understanding and hopefully spark new discussions leading to the development of new therapies including cell therapy and molecular target therapy, allowing clinicians to use more effective and less toxic approaches in the future. Hematological Disorders in Children will appeal to a wide readership, from medical students and beginning investigators to experienced scholars in the field of pediatric hematology and oncology seeking to broaden their understanding and keep up with the latest developments. It will also be of interest to the parents of pediatric patients, and to co-medical staffs.
Hematopoietic Stem Cells: The Basis of Normal and Malignant Hematopoiesis
Pages 3-29
Acute Lymphoblastic Leukemia
Pages 33-60
Acute Myeloid Leukemia
Pages 61-85
Myelodysplastic Syndrome (MDS) and Juvenile Myelomonocytic Leukemia (JMML)
Pages 87-108
Neutropenia (In Infancy and Childhood)
Pages 109-113
Childhood Aplastic Anemia
Pages 117-144
Inherited Bone Marrow Failure Syndrome, TAM
Pages 145-170
Immune and Inherited Thrombocytopenia in Children
Pages 173-187
Pathogenesis and Treatment of Hemophilia
Pages 189-204
Thrombotic Disorders
Pages 205-221
Langerhans Cell Histiocytosis
Pages 225-246
Primary Hemophagocytic Lymphohistiocytosis
Pages 247-261
Hemophagocytic Lymphohistiocytosis, Secondary
Pages 263-269
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