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Historical Aspects of Fungal Infections
Pages 3-9
This book provides comprehensive information on fungal infections of the central nervous system (CNS). Fungal infections are still a major public health challenge for most of the developing world and even for developed countries due to the rising numbers of immune compromised patients, refugee movements, and international travel. Although fungal infections involving the CNS are not particularly common, when they do occur, the results can be devastating in spite of recent advances and currently available therapies. Further, over the past several years, the incidence of these infections has seen a steep rise among immunodeficient patients. In this context, aggressive surgery remains the mainstay of management, but conservative antifungal drug treatment complemented by aggressive surgical debridement may be necessary. Yet the optimal management approach to fungal infections of the CNS remains controversial, owing to the limited individual experience and the variable clinical course of the conditions. Addressing that problem, this comprehensive book offers the ideal resource for neurosurgeons, neurologists and other specialists working with infectious diseases.
Historical Aspects of Fungal Infections
Pages 3-9
Epidemiology of Central Nervous System Fungal Infections
Pages 11-21
Morphological Classification of Fungal Infections (Yeasts, Mold, Dimorphic)
Pages 23-30
Pathogenesis of Fungal Infections
Pages 31-42
Predisposing Factors
Pages 43-49
Histopathology
Pages 51-73
Molecular Genetics and Genomics of Fungal Infections
Pages 75-88
Aspergillosis
Pages 91-105
Candidiasis
Pages 107-120
Mucormycosis
Pages 121-154
Histoplasmosis and Coccidioidomycosis
Pages 155-166
Cryptococcosis
Pages 167-185
Blastomycosis and Phaeohyphomycosis
Pages 187-194
Cladophialophora bantiana
Pages 195-204
Cladosporium spp., Fusarium spp., Bipolaris spp., Schizophyllum commune, and Scedosporium apiospermum
Pages 205-233
Cranial Vault Lesions
Pages 237-243
Meningitis and Meningoencephalitis
Pages 245-251
Raised Intracranial Pressure
Pages 253-257
Hydrocephalus
Pages 259-267
Intracranial Space-Occupying Lesions
Pages 269-274
Invasive Fungal Diseases of the Skull Base
Pages 275-288
Skull Base Clinical Syndromes
Pages 289-293
Orbito-Rhinocerebral Syndrome
Pages 295-303
Cavernous Sinus Syndrome
Pages 305-325
Intracranial Fungal Aneurysms
Pages 327-334
Acute Ischemic or Hemorrhagic Stroke Syndromes
Pages 335-343
Spinal Syndromes
Pages 345-350
Imaging of Fungal Infections of the Brain
Pages 353-365
Imaging Findings of Fungal Infections of the Cranial and Peripheral Nerves
Pages 367-386
Imaging Findings of Fungal Infections of the Sinuses Extending into the Brain
Pages 387-392
Imaging Findings of Fungal Infections of Spine and Spinal Cord
Pages 393-404
Surgical Therapy
Pages 407-414
Prognosis of Fungal Infections Involving the Central Nervous System and Its Coverings
Pages 415-420
Fungal Infections of the Spine Mimicking Tuberculosis
Pages 423-430
Fungal Infections in Cancer Patients
Pages 431-439
Invasive Fungal Infections in Patients with Hematologic Malignancies
Pages 441-449
Fungal Infections of Central Nervous System and Their Relationship to Neuropsychiatric Disorders
Pages 451-462
Real-Time PCR: Advanced Technologies and Applications
Pages 463-469
Next-Generation Sequencing: Current Technologies and Applications
Pages 471-474
Current Innovations and Future Trends
Pages 475-478
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