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This book summarizes evidence on frailty and ageing, how this may impact outcomes and how this can be incorporated in the decision-making process for cancer treatment. It discusses quality of life on frail senior adults and patient goals of care. The book aims to improve patient-treatment selection and the outcomes of patients by empowering clinicians to properly assess patients for frailty, either on their own or within a multidisciplinary setting.
The reader will learn the methods available for assessing for frailty, such as screening tools, but also how to perform geriatric assessments by providing details on each component (functional, nutritional, social, psychological, etc.). The book also provides information on how to manage and intervene on frailty with the role of pre-habilitation and re-habilitation, how to set-up frailty teams and pathways within one’s hospital and community. Finally, frailty and associated research per cancer type are discussed in detail along with biomarkers of frailty and future directions.
Pages i-ix
Pages 1-1
Introduction to Frailty in Older Adults with Cancer
Kristen Haase, Ines B. Menjak, Martine Puts
Pages 3-25
Global Action and Policies in Older Adults with Cancer and Frailty
Najia Musolino, Nicolò Matteo Luca Battisti, Martine Extermann
Pages 27-39
Frailty Screening and Comprehensive Geriatric Assessment
Lore Decoster, Gabor Liposits, Clark Dumontier
Pages 41-56
Cognitive Impairment in Older Adults with Cancer and Frailty
Lorraine Burgess, Cindy Kenis, Daniel Anderson
Pages 57-70
Psychosocial Dimension in Older Adults with Cancer and Frailty
Christian Bjerre-Real, Nikita Shah, Yesne Alici
Pages 71-91
Comorbidity and Polypharmacy in Older Adults with Cancer and Frailty
Arielle S. Berger, Mark Pearce, Leonor Matos, Shabbir M. H. Alibhai
Pages 93-112
Malnutrition, Cachexia, and Sarcopenia in Older Adults with Cancer and Frailty
Vérène Dougoud-Chauvin, Roman Dubianski, Anne-Catherine Barras-Moret
Pages 113-131
Physical Performance and Functional Status in Older Adults with Cancer and Frailty
Jenny Welford, Jennifer Woods, Sofia Duque, Fabio Gomes
Pages 133-152
Pages 153-153
Prehabilitation and Rehabilitation in Older Adults with Cancer and Frailty
Zoe Merchant, Linda Denehy, Daniel Santa Mina, Shabbir Alibhai, John Moore
Pages 155-176
Holistic Needs Assessment and Advance Care Planning in Older Adults with Cancer and Frailty
Jane Gibson, Sarah Wells, Cassandra Ng
Pages 177-188
Multidisciplinary Onco-Geriatric Care Models
Carolina Gómez-Moreno, Raúl Córdoba, Javier Martínez-Peromingo, José Alberto Avila-Funes, Enrique Soto-Perez-de-Celis
Pages 189-202
Decision-Making Process in Older Adults with Cancer and Frailty
Marije E. Hamaker, Grant Punnett, Janelle Yorke, Fabio Gomes
Pages 203-218
Perioperative Care in Older Adults with Cancer and Frailty
Sherena Nair, Simon J. Howell
Pages 219-233
Radiotherapy and Systemic Anti-Cancer Treatment in Older Adults with Cancer and Frailty
Anita O’Donovan, Capucine Baldini, Nicolò Matteo Luca Battisti
Pages 235-264
Palliative Care in Older Adults with Cancer and Frailty
Arvindselvan Mohanaselvan, Rex Paulino, Lily Wieland, Ishwaria Subbiah, Holly M. Holmes
Pages 265-277
Frailty Research: The Present and the Future
Martine Puts, Alastair Greystoke, Supriya Mohile
Pages 279-300
Pages 301-301
Breast Cancer in Older Adults with Frailty
Lissandra Dal Lago, Alex de Caluwe, Cindy Borghgraef, Laura Dumont, Thierry Pepersack
Pages 303-318
Non-Small Cell Lung Cancer in Older Adults with Frailty
Fabio Gomes, Kathryn Banfill, Andrea Bille, Stephanie Fraser, Giuseppe Banna
Pages 319-339
Colorectal Cancer in Older Adults with Frailty
Ana Ferreira, Louis J. Vitone, L. S. Prasad Kellati, Katie Ormston, Hassan Shikhrakab
Pages 341-355
Prostate Cancer in Older Adults with Frailty
Andrea Luciani, Cristina Falci, Fausto Petrelli, Giuseppe Colloca
Pages 357-370
Renal Cell Carcinoma in Older Adults with Frailty
Tanujaa Rajasekaran, Anupama Roy Chowdhury, Ravindran Kanesvaran
Pages 371-381
Cutaneous Melanoma in Older Adults with Frailty
Sophia Callaghan, Caroline Donovan, Paul Lorigan, Avinash Gupta
Pages 383-401
Gastroesophageal Cancer in Older Adults with Frailty
Daniel Swinson, Noor Mohammed, Andy Cockbain, Simon J. Howell, Mohan Hingorani
Pages 403-419
Hepatopancreaticobiliary Cancer in Older Adults with Frailty
Zainul Abedin Kapacee, Nicola de Liguori Carino, Angela Lamarca, Richard A. Hubner, Juan W. Valle, Mairéad G. McNamara
Pages 421-445
Gynaecological Cancer in Older Adults with Frailty
Christopher Steer, Bridget Josephs, Anthea Cree, Y. Louise Wan
Pages 447-466
Head and Neck Cancer in Older Adults with Frailty
Muhammad Shahid Iqbal, Eleanor Smith, Charles G. Kelly
Pages 467-480
Hematological Cancer in Older Adults with Frailty
Valentin Goede
Pages 481-493
Pages 495-501
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