Integrates the biochemical principles with physiological, pharmacological, and pathological aspects of human diseases
Each chapter features learning objectives, summaries, required and supplemental reading lists, clinical cases, and multiple-choice questions
Presents essential biochemical concepts within the context of their biological functions Offers instructional overview figures, flowcharts, tables and multi-colored illustrations
Provides an online ancillary package with PowerPoint images and an additional 500 study questions to aid in comprehension and USMLE exam preparation
1. The Human Organism: Organ Systems, Cells, Organelles, and Our Microbiota
2. Water, Acids, Bases, and Buffers
3. Amino Acids
4. Three-Dimensional Structure of Proteins and Disorders of Protein Misfolding
5. Energetics of Biological Systems, Enzymes and Enzyme Regulation
6. Clinical Enzymology and Biomarkers of Tissue Injury
7. Simple Carbohydrates
8. Heteropolysaccharides: Glycoconjugates, Glycoproteins, and Glycolipids
9. Connective Tissue: Fibrous and Nonfibrous Proteins and Proteoglycans
10. Gastrointestinal Digestion and Absorption
11. Carbohydrate Metabolism I: Glycolysis and the Tricarboxylic Acid Cycle
12. Electron Transport Chain, Oxidative Phosphorylation, and Other Oxygen-Consuming Systems
13. Carbohydrate Metabolism II: Gluconeogenesis, Glycogen Synthesis and Breakdown, and Alternative Pathways
14. Protein and Amino Acid Metabolism
15. Lipids I: Fatty Acids and Eicosanoids
16. Lipids II: Phospholipids, Glycosphingolipids, and Cholesterol
17. Lipids III: Plasma Lipoproteins
18. Contractile Systems
19. Perturbations of Energy Metabolism: Obesity and Diabetes Mellitus
20. Structure and Properties of DNA
21. DNA Replication, Repair, and Mutagenesis
22. RNA and Protein Synthesis
23. Regulation of Gene Expression
24. Nucleotide Metabolism
25. Hemoglobin and Metabolism of Iron & Heme
26. Endocrine Metabolism I: Introduction and Signal Transduction
27. Endocrine Metabolism II: Hypothalamus and Pituitary
28. Endocrine Metabolism III: Adrenal Glands
29. Endocrine Metabolism IV: Thyroid Gland
30. Endocrine Metabolism V: Reproductive System
31. Immunology
32. Biochemistry of Hemostasis
33. Mineral Metabolism
34. Vitamin Metabolism
35. Drug Metabolism