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Endocrine Pathology: Differential Diagnosis and Molecular Advances, Second Edition provides detailed coverage of endocrine pathology with extensive discussion of the differential diagnosis as well as presentation of molecular pathobiology of the major endocrine organs. Revised and expanded from the first edition, each chapter, written by leaders in their respective field, has been updated with the latest advances that are transforming the field of endocrine pathology. Richly illustrated with color photomicrographs, useful diagrams and line drawings, each chapter includes differential diagnosis of common and uncommon lesions as well as material on molecular developments, with emphasis on the molecular findings that are most helpful in the diagnosis of specific disorders.
Endocrine Pathology: Differential Diagnosis and Molecular Advances, Second Edition, provides a useful and well-organized resource designed not only for the endocrine pathologist and the general surgical pathologist, but also for the clinical endocrinologist and the endocrine surgeon.
vii
1 Methods in Cellular and Molecular Pathology...................................................... 1
Paul Komminoth, Axel Walch, Martin Werner,
and Aurel A. Perren
2 Hypothalamus and Neurohypophysis..................................................................... 45
Kazuhiro Takahashi, Osamu Murakami, and Toraichi Mouri
3 Tumors in the Adenohypophysis.............................................................................. 73
Fateme Salehi, Sergio Vidal, Eva Horvath, Kalman Kovacs,
and Bernd W. Scheithauer
4 Recent Developments in Molecular Embryogenesis and Molecular
Biology of the Pituitary............................................................................................. 91
Robert Y. Osamura and Noboru Egashira
5 Recent Developments in the Molecular Biology of Pituitary Tumors.................. 103
Ricardo V. Lloyd
6 The Pineal Gland...................................................................................................... 115
Katherine M. Lindstrom and M. Beatriz S. Lopes
7 The Parathyroid........................................................................................................ 131
H. Rubén Harach
8 Recent Developments in the Molecular Biology of the Parathyroid.................... 157
Vânia Nosé and Ashraf Khan
9 Pathology of Thyroid Gland..................................................................................... 181
Ashraf Khan and Vânia Nosé
10 Recent Developments in the Molecular Biology of the Thyroid........................... 237
Yuri E. Nikiforov
11 Adrenal Cortex.......................................................................................................... 261
Hironobu Sasano, Yasuhiro Nakamura, Takuya Moriya,
and Takashi Suzuki
12 Adrenal Medulla and Paraganglia.......................................................................... 281
Anne Marie McNicol
13 Molecular Biology of Pheochromocytomas and Paragangliomas........................ 297
Elizabeth E. King and Patricia L.M. Dahia
Contents
viii Contents
14 Endocrine Ovaries.................................................................................................... 307
Xavier Matias-Guiu
15 Endocrine Testis........................................................................................................ 333
Robert E. Emerson, Liang Cheng, and Thomas M. Ulbright
16 Endocrine Tumors of the Gastrointestinal System................................................ 351
Guido Rindi, Silvia Pizzi, Tiziana D’Adda, and Cesare Bordi
17 The Endocrine Pancreas........................................................................................... 367
Stefano La Rosa, Daniela Furlan, Fausto Sessa, and Carlo Capella
18 Neuroendocrine Differentiation Patterns in Various Organs
(Including Lung, Breast, Skin and Urogenital Tract)............................................ 415
Marco Volante, Anna Sapino, Mauro Papotti, Donatella Pacchioni,
and Gianni Bussolati
19 Endocrine Lung......................................................................................................... 429
William D. Travis
20 Cutaneous Neuroendocrine Tumors........................................................................ 447
Lori A. Erickson
21 Neuroendocrine Carcinomas of the Thymus.......................................................... 453
Cesar A. Moran and Saul Suster
22 Endocrine Placenta................................................................................................... 459
Raymond W. Redline
23 Fine Needle Aspiration Cytology of Endocrine Glands........................................ 473
Ema A. Dragoescu and Celeste N. Powers
24 Multiple Endocrine Neoplasia Syndrome............................................................... 493
Kennichi Kakudo, Yasuhiro Ito, and Masahide Takahashi
25 Polyglandular Autoimmune Diseases...................................................................... 523
Ricardo V. Lloyd
26 Biochemical Testing for Neuroendocrine Tumors.................................................. 527
Aaron I. Vinik and Maria P. Silva
27 Surgical Management of Endocrine Disorders...................................................... 545
Joseph B. Lillegard, Travis J. McKenzie, and Geoffrey B. Thompson
28 Medical Treatment of Neuroendocrine Tumors..................................................... 561
Timothy J. Hobday
29 Radiation Treatment of Endocrine Tumors........................................................... 567
Sunil Krishnan, Deepa Suresh, and Robert L. Foote
30 Future Directions in Endocrine Pathology............................................................. 581
Ricardo V. Lloyd
Index................................................................................................................................... 587
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