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Identifying Blood and Bone Marrow Abnormalities in the Laboratory
Pages 1-15
This book focuses on hematopoietic and lymphoid neoplasms that initially present as peripheral blood abnormalities, with either cytopenias or elevated peripheral blood counts, as well as non-neoplastic conditions that may raise concern for a hematologic malignancy. The scope of the book includes myelodysplastic syndromes (MDS), myeloproliferative neoplasms (MPN), mixed myelodysplastic/myeloproliferative neoplasms (MDS/MPN), as well as lymphomas and lymphoid leukemias that typically present initially with peripheral blood abnormalities. Within each category, a comprehensive list of differential diagnoses is discussed. For each disease entity, the reader is updated with new molecular genetic data, biomarkers, and recent applications of immunophenotyping, and how to incorporate the new information in disease diagnosis and classifications is illustrated, including the use of diagnostic algorithms where appropriate. The book employs the revised WHO Classification of Hematopoietic Neoplasms for all disease entities. Diagnosis of Blood and Bone Marrow Disorders will serve as a very useful resource for pathologists, pathologists in training, hematologists and medical technologists who are involved in the clinical work-up of patients with bone marrow and blood neoplasms. It will provide a practical and concise yet comprehensive review.
Sa A. Wang, MDAssociate Professor of Pathology Department of Hematopathology The University of Texas MD Anderson Cancer Center1515 Holcombe Blvd Houston, TX 770307137922603, swang5@mdanderson.org
Robert P. Hasserjian, MD Associate Professor of Pathology Department of Pathology Massachusetts General Hospital 55 Fruit Street 2 02114 6177241445, RHASSERJIAN@mgh.harvard.edu
1 b/w illustrations, 217 illustrations in colour
Identifying Blood and Bone Marrow Abnormalities in the Laboratory
Pages 1-15
Cytopenias: Reactive and Neoplastic
Pages 17-79
Inherited Bone Marrow Failure Syndromes, Myeloid Neoplasms with Germline Predisposition and Myeloid Proliferations Associated with Down Syndrome
Pages 81-117
Cytopenias: Acquired Bone Marrow Failure
Pages 119-134
Leukocytosis: Neutrophilia, Basophilia, and Blasts
Pages 135-170
Leukocytosis: Eosinophilia
Pages 171-193
Monocytosis
Pages 195-224
Thrombocytosis
Pages 225-242
Erythrocytosis
Pages 243-256
Mixed Cytoses and Cytopenias
Pages 257-279
T- and NK-Cell Lymphocytosis
Pages 281-328
B-Cell Lymphocytosis
Pages 329-381
Multiple Myeloma and Other Plasma Cell Neoplasms
Pages 383-403
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