Front Matter

Pages i-x

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Overview of Current Applied Knowledge

1. Front Matter

   Pages 1-1

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2. The Classification of Soft Tissue Tumors: Historical Aspects and Recent Advances

   • Andrew L. Folpe

   Pages 3-17

3. General Considerations in Magnetic Resonance Imaging of Soft-Tissue Tumors

   • Paolo Spinnato

   Pages 19-27

4. MRI Assessment of Surgical Margins, Residual Tumors and Recurring Lesions

   • Nicolò Gennaro

   Pages 29-41

5. Future Perspectives: Metabolic Imaging, Theranostics, and Radiomics

   • Jeffrey J. Peterson, Alexander D. Weston, Fatemeh Ataei

   Pages 43-53

6. The Role of Whole-Body Magnetic Resonance Imaging in Soft Tissue Tumors

   • Nefise Cagla Tarhan, Ercan Karaarslan

   Pages 55-64

7. Histopathologic Challenges in the Diagnostic Stage

   • A. H. G. Cleven, P. C. W. Hogendoorn

   Pages 65-71

8. Histological Challenges in the Intra-operative Stage

   • Suk Wai Lam, Judith V. M. G. Bovée

   Pages 73-80

9. Histopathological Challenges in the Postoperative Stages

   • Bilge Bilgic

   Pages 81-85

10. Staging of Soft Tissue Sarcomas

    • Michelle Ghert

    Pages 87-89

11. Should Prediction Models Decide Treatment?

    • Ibtissam Acem, Michiel A. J. van de Sande

    Pages 91-99

12. Medical Oncological Treatment of Adult Patients with Soft Tissue Sarcoma

    • Emine Hatipoglu, Robin L. Jones

    Pages 101-108

13. Medical Oncological Treatment of the Pediatric Patient

    • Stefan S. Bielack, Monika Sparber-Sauer, Claudia Blattmann

    Pages 109-116

14. Radiotherapy for Treatment of Adult Soft Tissue Sarcomas

    • Fulya Yaman Ağaoğlu

    Pages 117-124

15. IORT and Brachytherapy for Extremity Soft Tissue Sarcoma

    • Brady S. Laughlin, Safia K. Ahmed

    Pages 125-130

16. Classification from a Surgical Perspective

    • Harzem Özger, Buğra Alpan

    Pages 131-158

17. The Concept of Surgical Margins from a Surgical Perspective

    • Ajay Puri

    Pages 159-164

18. Is It Right, Safe, and Justified to Modulate the Margins?

    • Meshal K. Alfaraidy, Nicholas C. Eastley, Patrick Qi Wang, Anthony M. Griffin, Kim M. Tsoi, Jay S. Wunder et al.

    Pages 165-173

19. Surgical Strategy in Primary, Relapse, and “Whoops” Cases

    • Maria Danieli, Alessandro Gronchi

    Pages 175-185

20. Overview of Current Applied Knowledge

    1. Soft Tissue Sarcomas: Philosophy of Surgical Approach

       • Peter S. Rose

       Pages 187-192

    2. Principles of Upper Extremity Reconstruction Following Soft-Tissue Sarcoma Resection

       • Matthew T. Houdek, Brooke E. Willborg, Mikaela H. Sullivan, Karim Bakri, Steven L. Moran

       Pages 193-206

    3. Principles of Lower Extremity Reconstruction Following Soft Tissue Sarcoma Resection

       • Gavin L. Mills, Cory G. Couch

       Pages 207-217

    4. Extremity Soft Tissue Sarcoma: Assessing Treatment-Related Morbidity

       • Patrick Qi Wang, Nicholas C. Eastley, Meshal Alfaraidy, Anthony M. Griffin, Kim M. Tsoi, Peter C. Ferguson et al.

       Pages 219-231

    5. Assessing Functional Outcomes

       • Thomas Baad-Hansen, Sarah Stammose Freund

       Pages 233-238

    6. Prevention and Treatment of Complications

       • Levent Eralp, Buğra Alpan, Melih Civan, Harzem Özger

       Pages 239-244

    7. Management Algorithm for Extremity Soft Tissue Sarcomas

       • Harzem Özger, Franklin H. Sim, Ajay Puri, Levent Eralp, Buğra Alpan

       Pages 245-253

21. Case Studies

    1. Front Matter

       Pages 255-255

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    2. Soft-Tissue Sarcoma of the Thigh with Extensive Osseous Involvement

       • Ajay Puri

       Pages 257-263

    3. Liposarcoma of the Thigh: Multimodal Treatment and Long-Term Concerns

       • Maria Anna Smolle, Iva Brcic, Marko Bergovec, Jasminka Igrec, Bernadette Liegl-Atzwanger, Andreas Leithner

       Pages 265-274

    4. Malignant Tenosynovial Giant Cell Tumor of the Foot

       • Chandhanarat Chandhanayingyong

       Pages 275-281

    5. Synovial Sarcoma of the Forearm: Diagnostic Pitfalls and Biological Reconstruction

       • Harzem Özger, Cihangir Tetik, Buğra Alpan

       Pages 283-293

    6. Synovial Sarcoma of the Paravertebral Region with Osseous Involvement

       • Harzem Özger, Fatih Dikici, Buğra Alpan

       Pages 295-305

    7. Metastatic Mixed-Type Liposarcoma of the Popliteal Fossa: Multimodal Treatment

       • Buğra Alpan, Melih Civan, İpek G. Eralp, Yesim Eralp, Levent Eralp

       Pages 307-315

    8. Tenosynovial Giant Cell Tumour of the Foot with Osseous Involvement

       • Angus Crombie, Philip Rowell, James Bennett, Thomas Lloyd, Rino Olivotto, Peter Steadman

       Pages 317-324

    9. Visualization of Soft Tissue Sarcoma Margins Utilizing Indocyanine Green Fluorescence Angiography (ICGFA)

       • Matthew F. Gong, Kurt R. Weiss

       Pages 325-329

    10. Undifferentiated Pleomorphic Sarcoma of the Thigh: Diagnostic Pitfalls and Complex Reconstruction

        • Korhan Özkan, Erhan Okay, Enes Kanay

        Pages 331-336

    11. Undifferentiated Pleomorphic Sarcoma: Management of Recurrent Chest Wall Mass

        • Claire Park, Yazan Kadkoy, Joseph Ippolito, Edward Lee, Joseph Benevenia

        Pages 337-343

    12. Nonsurgical Management of Desmoid-Type Fibromatosis

        • Hiroyuki Tsuchiya, Akihiko Takeuchi

        Pages 345-349

    13. Wide Excision of a Large Sarcoma of the Pubic Region: Orthoplasty Reconstruction

        • Giuseppe Bianchi, Laura Campanacci

        Pages 351-354

    14. Case Studies

        1. Limb Salvage with Isolated Limb Perfusion in Soft Tissue Sarcoma

           • Lars Erik Podleska, Arne Streitbürger, Jendrik Hardes

           Pages 355-359

        2. Synovial Sarcoma of the Foot

           • Panayiotis J. Papagelopoulos, Ioannis Trikoupis, Panayiotis Gavriil

           Pages 361-366

        3. Multimodal Treatment and Functional Soft Tissue Reconstruction in Giant Liposarcoma of the Thigh

           • Panayiotis J. Papagelopoulos, Dimitra Melissaridou, Ioannis Trikoupis

           Pages 367-371

        4. Alternative to Extra-Articular Resection in Synovial Sarcoma of the Knee

           • Harzem Özger, Buğra Alpan

           Pages 373-383

        5. Limb Salvage Made Possible Through Neoadjuvant Treatment in Inoperable Infantile Fibrosarcoma

           • İnci Ayan, Harzem Özger, Buğra Alpan

           Pages 385-391

        6. Extensive Periosteum-Stripping Resection Without Prophylactic Femur Fixation in Thigh Tumors

           • Harzem Özger, Buğra Alpan

           Pages 393-401

        7. Exulcerated Angiosarcoma of the Head and Neck Treated with Neoadjuvant Chemoradiotherapy and Flap Reconstruction

           • Fulya Ağaoğlu, Harzem Özger, Mehmet Veli Karaaltın, Buğra Alpan

           Pages 403-408

        8. Soft Tissue Sarcoma of the Foot and Ankle: Wide Resection and Free Gracilis Flap

           • Philipp T. Funovics, Oskar Aszmann

           Pages 409-418

        9. Synovial Sarcoma of the Foot Treated with Recycled Bone Graft and Soft Tissue Reconstruction

           • Abigail R. Tud, Kuan-Lin Chen, Chao-Ming Chen, Wei Ming Chen

           Pages 419-422

        10. Recurrent Pleomorphic Sarcoma of the Thigh Treated with Radiotherapy and Total Femur Prosthesis

            • Abigail R. Tud, Kuan-Lin Chen, Chao-Ming Chen, Wei Ming Chen

            Pages 423-427

        11. Treating the Soft Tissue Tumor of the Hand

            • Wan Faisham Nu’man Wan Ismail, Arman Zaharil Mat Saad

            Pages 429-442

        12. Neoadjuvant Treatment Facilitating Surgery

            • E. J. Ortiz-Cruz, N. Bonsfills, M. Tapia-Viñé, B. Belinchon-Olmeda, A. Redondo, J. J. Pozo-Kreilinger

            Pages 443-450

        13. Soft Tissue Sarcoma in Contact with Bone: Is Bone Resection Indicated?

            • E. Pala, G. Trovarelli, M. C. Cerchiaro, P. Ruggieri

            Pages 451-456

        14. Soft Tissue Sarcoma with Osseous Invasion

            • Yang-Guk Chung

            Pages 457-465