Informazioni
Non ci sono recensioni
Punto di Riferimento
per Medici e Operatori Sanitari
per Medici e Operatori Sanitari
LIBRERIA STUDIUM
Cutaneous Neural Neoplasms
Argenyi, Jokinen
Editore
Springer
Anno
2011
Pagine
135
ISBN
9781603275811
100,00 €
- Differential diagnosis with tables and flowcharts
- Treatment summaries
- Generously illustrated, with various magnifications and explanatory symbols
- Includes histopathological features in tabulated form
As a result to the recent significant developments, both in the field of cutaneous pathology and clinical dermatology, many cutaneous neural tumors are now being diagnosed by specialists like dermatopathologists, and treated by dermatologists or dermatologic surgeons. Cutaneous Neural Neoplasms: A Practical Guide provides an essential aid in diagnosis by discussing the cardinal clinico-pathologic features of cutaneous tumors relevant to these specialists. It covers detailed pathologic features, and their differential diagnosis. Applicable special diagnostic techniques are extensively illustrated. Whenever relevant, key therapeutic recommendations are provided. The authors approach each entity by presenting clinical and/or gross photographs when relevant with discussion of the clinical features, followed by the tabulated list of key pathologic features with corresponding histopathologic illustrations. Therapeutic recommendations are summarized. Cutaneous Neural Neoplasms: A Practical Guide is an important new volume that fills a major gap in the currently available resources for practicing physicians, and provides them with an appropriate knowledge base to handle these challenging tumors in the most up-to-date fashion.
xi
Contents
1 The Peripheral Nerve and Cutaneous Neural Tumors:
Introduction, Definitions, and Classification ................................. 1
Additional Reading ............................................................................ 6
2 Special Techniques for the Study
of Cutaneous Neural Tumors .......................................................... 7
Additional Reading .......................................................................... 14
3 Nonneoplastic and Hamartomatous Lesions
of the Cutaneous Peripheral Nerve .............................................. 15
Palisaded Encapsulated Neuroma .................................................... 15
Definition, Classification, and Histogenesis................................ 15
Clinical Findings ......................................................................... 15
Histopathology ............................................................................ 15
Differential Diagnosis ................................................................. 21
Mucosal (Mucocutaneous) Neuroma ............................................... 21
Definition, Classification, and Histogenesis................................ 21
Clinical ........................................................................................ 21
Histopathology ............................................................................ 22
Differential Diagnosis ................................................................. 25
Fibrolipomatous Hamartoma ........................................................... 25
Definition, Classification, and Histogenesis................................ 25
Clinical ........................................................................................ 26
Histopathology ............................................................................ 26
Differential Diagnosis ................................................................. 26
Traumatic Neuroma ......................................................................... 26
Definition, Classification, and Histogenesis................................ 26
Clinical ........................................................................................ 26
Histopathology ............................................................................ 28
Differential Diagnosis ................................................................. 28
Morton’s Neuroma (Interdigital Neuritis) ........................................ 31
Definition, Classification, and Histogenesis................................ 31
Clinical ........................................................................................ 31
Histopathology ............................................................................ 31
Differential Diagnosis ................................................................. 31
xii Contents
Reparative Perineurial Hyperplasia ................................................. 33
Definition, Classification, and Histogenesis................................ 33
Clinical ........................................................................................ 33
Histopathology ............................................................................ 33
Differential Diagnosis ................................................................. 33
Epithelial Sheath Neuroma .............................................................. 33
Definition, Classification, and Histogenesis................................ 33
Clinical ........................................................................................ 33
Histopathology ............................................................................ 34
Differential Diagnosis ................................................................. 34
Additional Reading .......................................................................... 35
Palisaded Encapsulated Neuroma ............................................... 35
Mucosal Neuroma ....................................................................... 35
Fibrolipomatous Hamartoma of Nerve ....................................... 36
Reparative Perineurial Hyperplasia ............................................. 36
Epithelial Sheath Neuroma ......................................................... 36
4 Benign Cutaneous Neoplasms with Peripheral
Nerve Differentiation ..................................................................... 37
Neurofibroma ................................................................................... 37
Definition, Classification, and Histogenesis................................ 37
Clinical Findings ......................................................................... 37
Histopathology ............................................................................ 37
Differential Diagnosis ................................................................. 50
Schwannoma .................................................................................... 52
Definition, Classification, and Histogenesis................................ 52
Clinical ........................................................................................ 53
Histopathology ............................................................................ 53
Differential Diagnosis ................................................................. 68
Granular Cell Tumor ........................................................................ 68
Definition, Classification, and Histogenesis................................ 68
Clinical ........................................................................................ 68
Histopathology ............................................................................ 68
Differential Diagnosis ................................................................. 70
Nerve Sheath Myxoma .................................................................... 71
Definition, Classification, and Histogenesis................................ 71
Clinical ........................................................................................ 71
Histopathology ............................................................................ 72
Differential Diagnosis ................................................................. 74
Perineurioma .................................................................................... 76
Definition, Classification, and Histogenesis................................ 76
Clinical ........................................................................................ 76
Histopathology ............................................................................ 76
Differential Diagnosis ................................................................. 81
Lipoblastic Nerve Sheath Tumors .................................................... 81
Additional Reading .......................................................................... 81
Neurofibroma .............................................................................. 81
Schwannoma ............................................................................... 82
Contents xiii
Granular Cell Tumor ................................................................. 82
Nerve Sheath Myxoma .............................................................. 82
Perineurioma ............................................................................. 82
Lipoblastic Nerve Sheath Tumors ............................................. 82
5 Malignant Cutaneous Neoplasms with Peripheral
Nerve Differentiation ................................................................... 83
Malignant Peripheral Nerve Sheath Tumor ................................... 83
Definition, Classification, and Histogenesis.............................. 83
Clinical Findings ....................................................................... 83
Histopathology .......................................................................... 83
Differential Diagnosis ............................................................... 90
Malignant Granular Cell Tumor..................................................... 90
Definition, Classification, and Histogenesis.............................. 90
Clinical ...................................................................................... 90
Histopathology .......................................................................... 90
Differential Diagnosis ............................................................... 90
Additional Reading ........................................................................ 91
Malignant Peripheral Nerve Sheath Tumor ............................... 91
6 Cutaneous Proliferations with Putative
Neural Differentiation.................................................................. 93
Neurothekeoma .............................................................................. 93
Definition, Classification, and Histogenesis.............................. 93
Clinical Findings ....................................................................... 93
Histopathology .......................................................................... 93
Differential Diagnosis ............................................................... 101
Primary Cutaneous Neuroendocrine Carcinoma
(Merkel Cell Carcinoma) ............................................................... 103
Definition, Classification, and Histogenesis.............................. 103
Clinical ...................................................................................... 103
Histopathology .......................................................................... 104
Differential Diagnosis ............................................................... 108
Neurofollicular Hamartoma ........................................................... 109
Definition, Classification, and Histogenesis.............................. 109
Clinical ...................................................................................... 109
Histopathology .......................................................................... 109
Differential Diagnosis ............................................................... 109
Additional Reading ........................................................................ 111
Neurothekeoma ......................................................................... 111
Primary Cutaneous Neuroendocrine Carcinoma ....................... 111
Neurofollicular Hamartoma ...................................................... 111
7 Cutaneous Neuroblastic and Ganglion Cell Proliferations ...... 113
Neuroblastoma ............................................................................... 113
Definition, Classification, and Histogenesis.............................. 113
Clinical Findings ....................................................................... 113
Histologic Features.................................................................... 113
Differential Diagnosis ............................................................... 115
xiv Contents
Ganglioneuroma ............................................................................. 115
Definition, Classification, and Histogenesis.............................. 115
Clinical ...................................................................................... 115
Histopathology .......................................................................... 115
Differential Diagnosis ............................................................... 118
Ganglion Cell Choristoma ............................................................. 118
Definition, Classification, and Histogenesis.............................. 118
Clinical ...................................................................................... 118
Histopathology .......................................................................... 118
Differential Diagnosis ............................................................... 118
Additional Reading ........................................................................ 118
8 Cutaneous Glial and Meningothelial Proliferations ................. 119
Nasal Glioma (Heterotopic Glial Tissue) ....................................... 119
Definition, Classification, and Histogenesis.............................. 119
Clinical Findings ....................................................................... 119
Histopathology .......................................................................... 119
Differential Diagnosis ............................................................... 120
Cutaneous Meningioma ................................................................. 121
Definition, Classification, and Histogenesis.............................. 121
Clinical ...................................................................................... 121
Histopathology .......................................................................... 122
Differential Diagnosis ............................................................... 123
Meningocele ................................................................................... 123
Definition, Classification, and Histogenesis.............................. 123
Clinical ...................................................................................... 124
Histopathology .......................................................................... 124
Differential Diagnosis ............................................................... 126
Additional Reading ........................................................................ 126
Cutaneous Meningioma ............................................................ 126
Appendix: Practical Approach to Neural Tumors –
Flowcharts and Differential Diagnostic Tables ................................. 127
Index ...................................................................................................... 133
