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The book covers vigorously debated controversial topics in the field of critical care medicine over the years. It provides the reader with a balanced approach and guidance based on historical and currently available evidence in dealing with contentious clinical scenarios. The book reviews the most relevant, contemporaneous evidence on each topic and provides practical guidelines for clinical practice.
The book includes chapters that follow a structured approach to controversies related to specific organ systems. The topics covered provide a summary of the most relevant, practice-changing studies in the field of critical care medicine. Each topic describes the basic applied physiology, points of controversy, the evidence base, and summarizes the key points at the end. It includes brief description of landmark studies on each controversial topic.
The book serves as an important clinical guide to practitioners of critical care medicine when confronted with challenging clinical scenarios. Besides, it is a useful source of information to postgraduate trainees in various medical specialties. The topics addressed are among the most widely discussed during postgraduate examinations. It is also relevant for practitioners in general medicine and specialized areas of practice, including pulmonology (respiratory medicine), cardiology, neurology, nephrology, gastroenterology, and surgical specialties.
Pages i-xxvi
Front Matter
Pages 1-1
Oxygenation Targets in the ICU: Conservative or Liberal?
Pages 3-11
The Hypoxic Drive, Supplemental Oxygen, and Hypercapnia
Pages 13-18
Noninvasive Respiratory Support in Acute Hypoxemic Respiratory Failure
Pages 19-25
PEEP Titration by the Bedside: How Do We Set It Right?
Pages 27-35
Do Vigorous Spontaneous Respiratory Efforts Lead to Patient Self-Inflicted Lung Injury (P-SILI)?
Pages 37-45
Prone Ventilation in Acute Respiratory Distress Syndrome
Pages 47-54
Neuromuscular Blocking Agents in Severe Acute Respiratory Distress Syndrome: Benefit or Harm?
Pages 55-61
Ventilator-Associated Pneumonia: Newer Definitions, Controversies, and Perspectives
Pages 63-73
Lung-Protective Ventilation and Hypercapnia: How Much Is Permissible?
Pages 75-83
Tracheostomy in the ICU: Early or Late?
Pages 85-93
Diaphragmatic Dysfunction in Critical Illness
Pages 95-102
Weaning and Liberation from Mechanical Ventilation: Is My Patient Ready?
Pages 103-110
When to Decannulate a Tracheostomy?
Pages 111-118
Thrombolytic Therapy in Acute Pulmonary Embolism
Pages 119-128
Front Matter
Pages 129-129
Corticosteroids in Sepsis: The Enduring Debate
Pages 131-137
Hyperlactatemia in Critical Illness: Time for Reappraisal?
Pages 139-149
Permissive Hypotension in Severe Trauma
Pages 151-157
Assessment of Volume Responsiveness in the Critically Ill
Pages 159-166
Getting Rid of Excess Fluid: The Strategy of De-resuscitation
Pages 167-172
Are We Done with Early Goal-Directed Therapy?
Pages 173-178
Normal Saline Versus Balanced Crystalloids Revisited
Pages 179-187
Liberal Fluid Resuscitation Vs. Early Vasopressors in Septic Shock
Pages 189-197
Epinephrine and Outcomes Following Cardiac Arrest
Pages 199-205
Targeted Temperature Management in Out-of-Hospital Cardiac Arrest
Pages 207-214
Front Matter
Pages 215-215
Augmented Renal Clearance: When Supranormal Renal Function May Cause Harm
Pages 217-223
Renal Replacement Therapy in Acute Kidney Injury: Is Timing All Important?
Pages 225-231
Optimizing the Dose of Renal Replacement Therapy
Pages 233-239
Renal Replacement Therapy in the Critically Ill: Continuous Vs. Prolonged Intermittent Therapies
Pages 241-249
Front Matter
Pages 251-251
Does Intracranial Pressure Monitoring Help in Severe Traumatic Brain Injury?
Pages 253-259
Therapeutic Hypothermia in Traumatic Brain Injury
Pages 261-267
Decompressive Craniectomy in Traumatic Brain Injury
Pages 269-273
Optimization of Osmotherapy in Cerebral Edema
Pages 275-282
How Much Sedation in Critically Ill Patients on Mechanical Ventilation?
Pages 283-289
Delirium in the Intensive Care Unit: Are We Paying Enough Attention?
Pages 291-299
Clearing the Cervical Spine in Trauma Patients
Pages 301-307
Front Matter
Pages 309-309
Glycemic Control in the Critically Ill
Pages 311-317
Vitamin C in Sepsis: End of the Debate?
Pages 319-327
Front Matter
Pages 329-329
Early or Supplemental Parenteral Nutrition vs. Enteral Nutrition Alone in the Critically Ill
Pages 331-339
Stress Ulcer Prophylaxis in the Critically Ill
Pages 341-345
Do Tradition-Borne Fasting Practices Apply to ICU Patients with a Protected Airway?
Pages 347-352
Front Matter
Pages 353-353
Multidrug-Resistant Gram-Negative Bacteria in the ICU: Do We Have Answers?
Pages 355-364
Empirical Antibiotic Therapy: De-escalation Demystified
Pages 365-372
Is It the End of the Road for Inhaled Antibiotic Therapy in Ventilator-Associated Pneumonia?
Pages 373-380
Duration of Antibiotic Therapy in the Critically Ill
Pages 381-389
Selective Digestive Decontamination: Helpful or Harmful?
Pages 391-396
Front Matter
Pages 397-397
Which Organizational Structure to Pursue? The Open vs. Closed ICU Debate
Pages 399-405
Adverse Events in the ICU: Building and Sustaining an Organizational Culture of Patient Safety
Pages 407-413
How Effective Are Rapid Response Systems?
Pages 415-422
Front Matter
Pages 423-423
Transfusion Thresholds in Non-Bleeding Critically Ill Patients
Pages 425-435
Tranexamic Acid in the Bleeding Patient
Pages 437-446
Dengue-Related Thrombocytopenia and Platelet Transfusion
Pages 447-454
Front Matter
Pages 455-455
Pages 457-468
Pages 469-472
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