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Cluster Headache and Related Syndromes in History and Literature
Pages 1-6
This book provides essential insights into the current state of knowledge regarding the main aspects of cluster headache and trigeminal autonomic cephalgias. The first chapters focus on classification and clinical features, together with familial and genetic aspects. Relevant animal models and the putative role of key nervous structures as the hypothalamus, brainstem, diencephalon and sphenopalatine ganglion are reviewed. Evidence gained from key molecules such as CGRP in animals and human headache models are discussed.
The book subsequently presents information on the various aspects of the pathophysiology of trigeminal autonomic cephalalgias for example regarding the implication of the trigeminovascular system and the facial autonomic reflexes of the brainstem. Further, it shares insights from imaging studies including functional magnetic resonance imaging and more advanced techniques, as well as brain stimulation procedures. Further chapters describe the current st
ate of knowledge concerning drug treatment and the various neurostimulation procedures. Trigeminal neuralgia is also presented, due its close relationship with some short-term trigeminal autonomic cephalgias: a great deal can be learned from a better understanding of their differences and similarities. The same approach is then applied to cluster headache and migraine.
All chapters were written by respected experts in their fields, ensuring the book will provide an excellent source of up-to-date information and perspectives on trigeminal autonomic cephalgias and related disorders. As such, it will be of considerable value for students, clinicians and pain researchers alike.
Cluster Headache and Related Syndromes in History and Literature
Pages 1-6
Epidemiology of Cluster Headache
Pages 7-10
Classification and Clinical Features
Pages 11-21
Differential Diagnosis, Including Secondary Forms
Pages 23-41
Genetics of Cluster Headache and Other Trigeminal Autonomic Cephalalgias
Pages 43-56
Pathophysiological Considerations Regarding Cluster Headache and Trigeminal Autonomic Cephalalgias
Pages 57-66
Neuroimaging in Cluster Headache and Trigeminal Autonomic Cephalalgias
Pages 67-90
Some Observations About the Origin of the Pain in Cluster Headache
Pages 91-101
Animals Models for Trigeminal Autonomic Cephalalgias
Pages 103-115
The Role of the Sphenopalatine Ganglion in Headache Conditions: New Insights
Pages 117-129
Acute Treatment of Cluster Headache Attacks
Pages 131-134
Prophylactic Drugs
Pages 135-151
Neurostimulation: Why, When, and Which One?
Pages 153-167
Behavioral and Psychological Aspects, Quality of Life, and Disability and Impact of Cluster Headache
Pages 169-187
Neurophysiology of Cluster Headache and Other Trigeminal Autonomic Cephalalgias
Pages 189-208
Trigeminal Neuralgia: Channels, Pathophysiology, and Therapeutic Challenges
Pages 209-219
Migraine and Cluster Headache: Differences and Similarities
Pages 221-236
The Short-Lasting Headaches Including Hypnic Headache
Pages 237-255
Future Therapies for Trigeminal Autonomic Cephalalgias: Cluster Headache and Related Conditions
Pages 257-264
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