Titolo: Clinical Molecular Diagnostics

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Clinical Molecular Diagnostics

Editore

Springer

Anno

2022

Pagine

890

ISBN

9789811610394

I prezzi indicati possono subire variazioni poiché soggetti all'oscillazione dei cambi delle valute e/o agli aggiornamenti effettuati dagli Editori.

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This book covers the discovery of molecular biomarkers, the development of laboratory testing techniques and their clinical applications, focusing on basic research to clinical practice. It introduces new and crucial knowledge and ethics of clinical molecular diagnosis. This book emphasizes the applications of clinical molecular diagnostic test on health management, especially from different diseased organs. It lets readers to understand and realize precision healthcare.

Front Matter

Pages i-xxviii

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Principles of Clinical Molecular Diagnostics
1. Front Matter
  
  Pages 1-1
  
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2. Molecules of Disease and Their Detection Methods
  - Lutao Du, Chuanxin Wang
  Pages 3-9
3. Assay Performance Evaluation
  - Lixin Wang, Zhiyun Shi
  Pages 11-26
4. Establishment of Biological Reference Interval
  - Lixin Wang, Zhiyun Shi
  Pages 27-37
5. Ethics: Informed Consent, Patient Privacy
  - Qinghe Meng, Xu Qian
  Pages 39-44
6. Bioinformatics
  - Chenglu He, Yong Duan
  Pages 45-59
7. Report and Consultation
  - Yongqing Tong
  Pages 61-90
8. Factors Associated with Variation
  - Xue Qin
  Pages 91-95
9. Quality Control and Quality Assurance
  - Gaowei Fan, Qingtao Wang
  Pages 97-113
10. Precision Medicine
  - Yingping Cao, Xianjin Zhu
  Pages 115-120
Molecular Biomarkers and Signals from Diseased Functional Organ
1. Front Matter
  
  Pages 121-121
  
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2. Molecules in Body Systems
  - Shiyang Pan, Xincen Duan
  Pages 123-137
3. Molecules in Signal Pathways
  - Shiyang Pan, Wei Zhang
  Pages 139-154
4. Endocrine and Metabolism
  - Shichang Zhang, Xiaoting Chen
  Pages 155-166
5. Immune System
  - Xiuru Guan
  Pages 167-177
6. Lipoproteins
  - Changmin Wang, Zhiwei Li
  Pages 179-193
7. Transport and Carrier Proteins
  - Changmin Wang, Zhiwei Li
  Pages 195-205
8. Coagulation and Fibrinolysis
  - Hong Wang, Yun Ling
  Pages 207-219
9. Cardiovascular System
  - Haitao Ding, Juan He
  Pages 221-227
10. Molecular Biomarkers and Signals from Diseased Functional Organ
  1. Pregnancy
    - Xianzhang Huang, Enyu Liang
    Pages 229-240
  2. Urine
    - Bingfeng Zhang, Qing Li
    Pages 241-252
  3. Bone
    - Lieying Fan
    Pages 253-259
  4. Cancer
    - Wenling Zhang, Yumei Huang, Jian Xu
    Pages 261-284
  5. Translation Research of Novel Biomarker
    - Shiyang Pan, Yuexinzi Jin
    Pages 285-301
11. Advanced Molecular Diagnostic Techniques
  1. Front Matter
    
    Pages 303-303
    
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  2. Next-Generation Sequencing (NGS)
    - Min Wang
    Pages 305-327
  3. Digital PCR
    - Min Wang, Xianping Li
    Pages 329-344
  4. Biosensor
    - Lei Zheng, Ye Zhang
    Pages 345-356
  5. Microfluidic Chip
    - Xueen Fang
    Pages 357-375
  6. Liquid Biopsy
    - Jianyu Rao, Weibo Yu, Teresa Kim, Thomas Lee
    Pages 377-394
  7. Molecular-Targeted Imaging
    - Fang Wang, Jian Xu, Wenying Xia
    Pages 395-404
  8. Fluorescence In Situ Hybridization
    - Min Hu, Weimin Wu
    Pages 405-411
  9. Circulating DNA Quantification
    - Min Hu, Zeyou Wang
    Pages 413-426
  10. DNA Methylation Detection Techniques
    - Shiyang Pan, Jiexin Zhang
    Pages 427-435
12. Disease Presentation and Clinical Laboratory Procedures
  1. Front Matter
    
    Pages 437-437
    
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  2. Immunological Disorders
    - Hong Mu, Chunlei Zhou, Ling Fang, Feng Xie, Yan Zhang, Huanhuan Chen
    Pages 439-461
  3. Liver Diseases
    - Qishui Ou, Hong Mu, Chunlei Zhou, Zhaojing Zheng, Juan Geng
    Pages 463-492
  4. Pancreatic Diseases
    - Lu Yang, Huanyu Ju, Yuan Mu, Chunrong Gu
    Pages 493-509
  5. Digestive Tract Disease
    - Genyan Liu, Yuqiao Xu, Shiyang Pan, Weijuan Song, Jia Wang, Fei Jin et al.
    Pages 511-552
  6. Disease Presentation and Clinical Laboratory Procedures
    1. Kidney Diseases
      - Zhaojing Zheng, Juan Geng, Ye Jiang, Meijuan Zhang, Ruixia Yang, Gaoxia Ge et al.
      Pages 553-582
    2. Cardiovascular Disease
      - Zhou Zhou, Yahui Lin
      Pages 583-594
    3. Lung Disease
      - Liang Ming, Ting Sun, Haitao Ding, Juan He, Wenjuan Wu, Min Zhang et al.
      Pages 595-640
    4. Blood Disorders
      - Zhuang Zuo, Cheng Cameron Yin, Lixia Zhang, Lin Wang, Zhen Ren
      Pages 641-664
    5. Endocrine and Metabolic Diseases
      - Hong Yuan, Jingyuan Zhao, Erfu Xie, Lujiang Yi, Zhaojing Zheng, Juan Geng
      Pages 665-716
    6. Neurological Disease
      - Jie Wu, Yutong Zou, Yingchun Xu, Mengxiao Xie, Zhaojing Zheng, Juan Geng
      Pages 717-749
    7. Reproductive Organ Cancer
      - Jinhai Tang, Xiangjun Cheng, Jieshi Xie, Zheng Cao, Yanhong Zhai, Boyan Song
      Pages 751-768
    8. Prenatal Diagnosis and Preimplantation Genetic Diagnosis
      - Chengcheng Liu, Xiaoting Lou, Jianxin Lyu, Jian Wang, Yufei Xu
      Pages 769-800
    9. Transplant Matching
      - Binwu Ying, Lijuan Wu
      Pages 801-811
    10. Paternity Testing
      - Binwu Ying, Juan Zhou
      Pages 813-820
  7. Back Matter
    
    Pages 821-889