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Introduction to Sympathetic Microneurography
Pages 3-11
This book describes newly developed methods of assessing the autonomic nervous system. Up-to-date information on microneurographic analysis of human cardiovascular and thermoregulatory function in humans, heart rate variability, and 131I-metaiodobenzylguanidine (MIBG) scintigraphy are provided. Microneurography, which was originally developed as a technique to analyze the afferent muscle spindle, came to be used to analyze sympathetic nerve activity in the mid-1980s. In the twenty-first century, this technique has become prevalent all over the world especially in investigating the pathophysiology of human cardiovascular function. It is also now used in researching human thermoregulatory function. Heart rate variability is another valuable tool in investigating the current status of human vagal function and in predicting future cardiovascular disease. MIBG is also used to assess cardiac noradrenergic function, especially decreases associated with Parkinson’s disease, Lewy body disease, and multisystem atrophy. Overviews of recent advances in these three important assessments are provided by leading experts.Clinical Assessment of the Autonomic Nervous System is a useful resource for neurologists and researchers of clinical neurophysiology.
Introduction to Sympathetic Microneurography
Pages 3-11
Muscle Sympathetic Nerve Activity in Neurological Disorders
Pages 13-30
Muscle Sympathetic Nerve Activity and Cardiovascular Disease
Pages 31-46
Skin Sympathetic Nerve Activity and Thermoregulatory Control in Humans
Pages 47-71
Muscle Sympathetic Nerve Activity and Syncope
Pages 73-92
Single Fiber Analysis of Muscle Sympathetic Nerve Activity
Pages 93-105
Introduction to Heart Rate Variability
Pages 109-127
Respiratory Sinus Arrhythmia and Entraining Heartbeats with Cheyne-Stokes Respiration: Cardiopulmonary Works to Be Minimal by Synchronizing Heartbeats with Breathing
Pages 129-146
Heart Rate Variability (HRV) and Sympathetic Nerve Activity
Pages 147-161
Heart Rate Variability and Cardiac Diseases
Pages 163-178
Heart Rate Variability and Neurological Disorders
Pages 179-197
An Introduction to MIBG Cardiac Scintigraphy
Pages 201-205
Noradrenaline and
Pages 207-217
Technical Considerations for MIBG Cardiac Scintigraphy
Pages 219-230
Findings of
Pages 231-257
Findings of MIBG Cardiac Scintigraphy: Dementia with Lewy Bodies and Related Dementia
Pages 259-270
Physiological Background of Reduced Cardiac
Pages 271-289
Pathological Background of Reduced Cardiac MIBG Uptake
Pages 291-311
Clinical Implications of Reduced Cardiac MIBG Uptake
Pages 313-317
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