Table of Contents:

1. Sleep in Art and Literature

2. History of Sleep Medicine and Physiology

3. The Biology of Sleep

3.1. Sleep Mechanisms

3.2. Localization and Neurochemistry of Sleep-Wake Physiology & Pathophysiology

3.3. Circadian Rhythms Regulation

3.4. Physiologic Regulation in Sleep

3.5. Cytokines, Host Defense, and Sleep

3.6. Control of Breathing

3.7. Central and Autonomic Regulation in Cardiovascular Physiology

3.8. Interactive Regulation of Sleep and Feeding

3.9. Endocrine Physiology

4. Normal Sleep

4.1. Sleep in Animals and the Phylogeny of Sleep

4.2. Normal Sleep in Humans

5. Sleep Restriction

6. Pharmacology

7. Dreaming in Normal and Disrupted Sleep

8. Impact, Presentation, and Diagnostic Considerations

9. Circadian System Disorders

9.1. Circadian Rhythm Disorders

9.2. Circadian Desynchrony and Health

10. Insomnia

11. Neurologic Disorders

11.1. Central Nervous System Hypersomnias

11.2. Movement Disorders in Sleep

11.3. Sleep and Epilepsy

11.4. Sleep in Other Neurologic Disorders

12. Parasomnias

13. Sleep Breathing Disorders

13.1. Examination of the Patient with Suspected Sleep Apnea

13.2. Sleep Apnea in the Adolescent and Adult

13.3. Obstructive Sleep Apnea in Children

13.4. Respiratory Diseases and the Overlap Syndromes

14. Vascular Disorders

14.1. Cardiovascular Diseases

14.2. Cerebrovascular Disease and Sleep

15. Other Medical Disorders

15.1. Thyroid Disease

15.2. Diseases of the Pituitary Gland

15.3. Gastrointestinal Disorders

15.4. Diabetes Mellitus

15.5. Sleep Disorders in Chronic Kidney Disease

16. Women’s Health

16.1. The Menstrual Cycle

16.2. Pregnancy and Postpartum

16.3. Midlife Transition and Menopause

16.4. Chronic Fatigue and Fibromyalgia Syndromes

17. Sleep and Psychiatric Disease

18. Diagnostic Assessment Methods in Adults

19. Gallery of Polysomnographic Recordings

20. Gallery of Patient Interview Videos

21. Gallery of Sleep Laboratory Video Findings

Index