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Skeletal Muscle Biopsy Evaluation
Pages 3-48
This book provides a practical guide to the field of neuromuscular pathology including muscle, peripheral nerve, and skin biopsies with biopsy interpretation. Divided into three parts, the book begins with introductory chapters that review muscle, nerve, and skin biopsy indications and procedures, normal muscle and nerve histology, and common muscle and nerve pathology. The 28 myopathy case chapters in Part 2 and 11 neuropathy case chapters in Part 3 illustrate the clinical and pathological features of many neuromuscular diseases, demonstrate the indications and utilities of biopsies, discuss clinical and pathological differential diagnosis, update the individual disease management, and summarize pertinent clinical and pathology pearls for each case.
A Case-Based Guide to Neuromuscular Pathology will function as an indispensable reference for neurologists and pathologists looking to understand the utility of muscle, nerve, and skin biopsies. This book will also aid neurology residents, neuromuscular fellows and neuropathology fellows in preparing for questions related to the muscle and nerve pathology in their in-service and board exams.
Skeletal Muscle Biopsy Evaluation
Pages 3-48
Peripheral Nerve Biopsy Evaluation
Pages 49-73
Skin Biopsy with Cutaneous Nerve Fiber Evaluation
Pages 75-88
A 20-Year-Old Man with Acute Multi-organ Failure and Rhabdomyolysis
Pages 91-95
A 45-Year-Old Woman with Proximal Limb Weakness and Skin Peeling on Fingertips
Pages 97-108
A 75-Year-Old Man with Slowly Progressive Leg and Hand Weakness
Pages 109-119
A 53-Year-Old Woman with Proximal Limb Weakness and Marked CK Elevation
Pages 121-129
A 61-Year-Old Woman with Progressive Distal Limb and Deltoid Muscle Weakness
Pages 131-136
A 63-Year-Old Woman with Debilitating Muscle Pain
Pages 137-143
A 33-Year-Old Woman with Pain and Swelling in the Right Calf and Persistent Fever
Pages 145-149
A 28-Year-Old Woman with Proximal Limb Weakness and Scapular Winging
Pages 151-157
A 52-Year-Old Man with Proximal Limb Weakness and Hand Stiffness
Pages 159-166
A 51-Year-Old Woman with Long-Standing Exercise Intolerance
Pages 167-174
A 37-Year-Old Woman with Leg Weakness and CK Elevation
Pages 175-184
A 25-Year-Old Woman with Droopy Eyelids and Double Vision
Pages 185-194
A 58-Year-Old Man with Hypercapnic Respiratory Failure
Pages 195-202
A 65-Year-Old Man with Asymmetrical Leg Weakness and Foot Tingling
Pages 203-211
A 40-Year-Old Man with Muscle Pain and Fatigue
Pages 213-220
A 42-Year-Old Woman with Progressive Limb Weakness and Breathing Difficulty
Pages 221-227
A 49-Year-Old Man with Limb Weakness and Painful Skin Lesions
Pages 229-232
A 54-Year-Old Man with Progressive Lower Limb Weakness and CK Elevation
Pages 233-241
A 63-Year-Old Man with Progressive Limb Weakness and Slurred Speech
Pages 243-250
A 6-Year-Old Girl with Muscle Pain and Swelling in the Thighs
Pages 251-256
A 4-Year-Old Boy with Progressive Weakness, Difficulty Walking and Running, and Increased Falls
Pages 257-262
A 2-Year-Old Girl with Hypotonia Since Birth and Delayed Motor and Speech Development
Pages 263-268
An 8-year-old boy with delayed motor milestones and proximal leg muscle weakness
Pages 269-274
A 6-Year-Old-Boy with Proximal Leg Muscle Weakness and Facial Weakness
Pages 275-281
A 6-Week-Old Boy with Neonatal Hypotonia and Feeding and Respiratory Difficulties
Pages 283-288
A 6-Year-Old Boy with Respiratory and Feeding Difficulties at Birth, Delayed Gross Motor Milestones, and Facial and Proximal Lower Limb Weakness
Pages 289-296
A 12-Year-Old Girl with a 2-Year History of Progressive Limb Weakness and Difficulties with Exercise
Pages 297-302
A 3-Month-Old Boy with Generalized Hypotonia, Weakness, Pneumonia and Respiratory Failure
Pages 303-308
A 59-Year-Old Woman with Subacute Lower Limb Weakness and Painful Paresthesia
Pages 311-317
A 63-Year-Old Man with Nausea, Vomiting, Orthostatic Dizziness, and Distal Limb Paresthesia
Pages 319-327
A 47-year-old woman with progressive numbness and weakness in the limbs
Pages 329-334
A 65-Year-Old Woman with Acute Limb Weakness and Worsening of Paresthesia
Pages 335-341
A 34-Year-Old Man with Right Hand and Left Foot Numbness
Pages 343-348
A 64-Year-Old Woman with Progressive Pain, Numbness and Weakness in the Right Lower Limb
Pages 349-356
A 68-Year-Old Man with Progressive Lower Limb Numbness and Weakness and Urinary Incontinence
Pages 357-363
A 53-Year-Old Woman with Pain, Burning, Tingling, and Numbness in the Distal Limbs
Pages 365-373
A 40-Year-Old Woman with Patchy Painful Paresthesia
Pages 375-380
A 39-Year-Old Woman with Intermittent Bilateral Foot and Leg Pain since Childhood
Pages 381-387
A 35-Year-Old Man with Pain and Numbness in the Left Lateral Thigh
Pages 389-394
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